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Application of WST-8 based colorimetric NAD(P)H detection for quantitative dehydrogenase assays

The reduction of tetrazolium salts by NAD(P)H to formazan product has been widely used to determine the metabolic activity of cells, and as an indicator of cell viability. However, the application of a WST-8 b...

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Association of TM6SF2 rs58542926 gene polymorphism with the risk of non-alcoholic fatty liver disease and colorectal adenoma in Chinese Han population

Genetic factors affect the risk of non-alcoholic fatty liver disease (NAFLD) and colorectal adenoma (CRA) importantly. Transmembrane protein 6 superfamily member 2 (TM6SF2) rs58542926 is a significant genetic ...

The active role of the transcription factor Sp1 in NFATc2-mediated gene regulation in pancreatic cancer

Adenocarcinoma of the pancreas is one of the most aggressive tumor diseases affecting the human body. The oncogenic potential of pancreatic cancer is mainly characterized by extremely rapid growth triggered by...

Role of the highly conserved G68 residue in the yeast phosphorelay protein Ypd1: implications for interactions between histidine phosphotransfer (HPt) and response regulator proteins

Many bacteria and certain eukaryotes utilize multi-step His-to-Asp phosphorelays for adaptive responses to their extracellular environments. Histidine phosphotransfer (HPt) proteins function as key components ...

Up-regulation of DcR3 in microbial toxins-stimulated HUVECs involves NF-κB signalling

Sepsis is a severe condition characterised by the body’s systemic inflammatory response to infection. The specific sepsis-related biomarkers should be used in clinical diagnosis, therapeutic response monitorin...

Soluble expression of recombinant midgut zymogen (native propeptide) proteases from the Aedes aegypti Mosquito Utilizing E. coli as a host

Studying proteins and enzymes involved in important biological processes in the Aedes aegypti mosquito is limited by the quantity that can be directly isolated from the mosquito. Adding to this difficulty, digest...

Identification of the major diacylglycerol acyltransferase mRNA in mouse adipocytes and macrophages

Triacylglycerols (TAGs) are the major form of energy storage in eukaryotes. Diacylglycerol acyltransferases (DGATs) catalyze the final and rate-limiting step of TAG biosynthesis. Mammalian DGATs are classified...

Purification and characterization of cysteine protease from miswak Salvadora persica

Generally, proteases in medicinal plants had different therapeutic effects such as anti-inflammatory effect; modulate the immune response and inhibitory effect toward tumor growth. In this study, protease was ...

Effect of IAPP on the proteome of cultured Rin-5F cells

Islet amyloid polypeptide (IAPP) or amylin deposits can be found in the islets of type 2 diabetes patients. The peptide is suggested to be involved in the etiology of the disease through formation of amyloid d...

Structure and function of a lignostilbene-α,β-dioxygenase orthologue from Pseudomonas brassicacearum

Stilbene cleaving oxygenases (SCOs), also known as lignostilbene-α,β-dioxygenases (LSDs) mediate the oxidative cleavage of the olefinic double bonds of lignin-derived intermediate phenolic stilbenes, yielding ...

Simple spectrophotometric assay for measuring catalase activity in biological tissues

The details of a precise, accurate, and sensitive spectrophotometric method for measuring catalase activity are presented here. The assay was established for biological samples and depends on the rapid formati...

Establishment of a detection assay for DNA endonuclease activity and its application in the screening and prognosis of malignant lymphoma

Endonucleases play critical roles in maintaining genomic stability and regulating cell growth. The purpose of this study was to evaluate detection of endonuclease activity as an indicator in the early diagnosi...

Isolation of quercetin and mandelic acid from Aesculus indica fruit and their biological activities

In this study Aesculus indica fruit was subjected to isolation of phytochemicals. Two antioxidants quercetin and Mandelic acid were isolated in pure state. The free radical scavenging and acetyl choline esterase ...

Purification and characterization of α-amylase from Trichoderma pseudokoningii

Previous studies have demonstrated that members of Trichoderma are able to generate appreciable amount of extracellular amylase and glucoamylase on soluble potato starch. In this study the α-amylase was purified ...

Identification and characterization of smallest pore-forming protein in the cell wall of pathogenic Corynebacterium urealyticum DSM 7109

Corynebacterium urealyticum , a pathogenic, multidrug resistant member of the mycolata, is known as causative agent of urinary tract infections although it is a bacterium of the skin flora. This pathogenic bacteri...

Characterization of association of human mitochondrial lysyl-tRNA synthetase with HIV-1 Pol and tRNA 3 Lys

An important step in human immunodeficiency virus type 1 (HIV-1) replication is the packaging of tRNA 3 Lys from the host cell, which plays the role of primer RNA in the process of initiation of reverse transcripti...

Feruloyl esterase immobilization in mesoporous silica particles and characterization in hydrolysis and transesterification

Enzymes display high reactivity and selectivity under natural conditions, but may suffer from decreased efficiency in industrial applications. A strategy to address this limitation is to immobilize the enzyme....

Characterization of sulfhydryl oxidase from Aspergillus tubingensis

Despite of the presence of sulfhydryl oxidases (SOXs) in the secretomes of industrially relevant organisms and their many potential applications, only few of these enzymes have been biochemically characterized...

Glycyl-alanyl-histidine protects PC12 cells against hydrogen peroxide toxicity

Peptides with cytoprotective functions, including antioxidants and anti-infectives, could be useful therapeutics. Carnosine, β-alanine-histidine, is a dipeptide with anti-oxidant properties. Tripeptides of Ala...

Antiproliferative factor (APF) binds specifically to sites within the cytoskeleton-associated protein 4 (CKAP4) extracellular domain

Antiproliferative factor (APF) is a sialoglycopeptide elevated in the urine of patients with interstitial cystitis—a chronic, painful bladder disease. APF inhibits the proliferation of normal bladder epithelia...

Use of a special Brazilian red-light emitting railroad worm Luciferase in bioassays of NEK7 protein Kinase and Creatine Kinase

Luciferases, enzymes that catalyze bioluminescent reactions in different organisms, have been extensively used for bioanalytical purposes. The most well studied bioluminescent system is that of firefly and oth...

Dacin, one metalloproteinase from Deinagkistrodon acutus venom inhibiting contraction of mouse ileum muscle

Mice were bitten by five-pace vipers ( Deinagkistrodon acutus ), and then envenomed. It was well-known that the snake venom mainly disturbed the blood homeostasis of the envenomed victims. Ocassionally, we found th...

Serendipitous discovery of light-induced ( In Situ ) formation of an Azo-bridged dimeric sulfonated naphthol as a potent PTP1B inhibitor

Protein tyrosine phosphatases (PTPs) like dual specificity phosphatase 5 (DUSP5) and protein tyrosine phosphatase 1B (PTP1B) are drug targets for diseases that include cancer, diabetes, and vascular disorders ...

Chemical and structural characterization of α-N-acetylgalactosaminidase I and II from starfish, asterina amurensis

The marine invertebrate starfish was found to contain a novel α-N-acetylgalactosaminidase, α-GalNAcase II, which catalyzes removal of terminal α-N-acetylgalactosamine (α-GalNAc), in addition to a typical α-N-a...

Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase Ldt Mt2 by biapenem and tebipenem

The carbapenem subclass of β-lactams is among the most potent antibiotics available today. Emerging evidence shows that, unlike other subclasses of β-lactams, carbapenems bind to and inhibit non-classical tran...

Structural similarities and functional differences clarify evolutionary relationships between tRNA healing enzymes and the myelin enzyme CNPase

Eukaryotic tRNA splicing is an essential process in the transformation of a primary tRNA transcript into a mature functional tRNA molecule. 5′-phosphate ligation involves two steps: a healing reaction catalyze...

CrMAPK3 regulates the expression of iron-deficiency-responsive genes in Chlamydomonas reinhardtii

Under iron-deficient conditions, Chlamydomonas exhibits high affinity for iron absorption. Nevertheless, the response, transmission, and regulation of downstream gene expression in algae cells have not to be inve...

Binding of smoothelin-like 1 to tropomyosin and calmodulin is mutually exclusive and regulated by phosphorylation

The smoothelin-like 1 protein (SMTNL1) can associate with tropomyosin (Tpm) and calmodulin (CaM), two proteins essential to the smooth muscle contractile process. SMTNL1 is phosphorylated at Ser301 by protein ...

Increased enzymatic hydrolysis of sugarcane bagasse by a novel glucose- and xylose-stimulated β-glucosidase from Anoxybacillus flavithermus subsp. yunnanensis E13 T

β-Glucosidase is claimed as a key enzyme in cellulose hydrolysis. The cellulosic fibers are usually entrapped with hemicelluloses containing xylose. So there is ongoing interest in searching for glucose- and x...

Interactions of histatin-3 and histatin-5 with actin

Histatins are histidine rich polypeptides produced in the parotid and submandibular gland and secreted into the saliva. Histatin-3 and −5 are the most important polycationic histatins. They possess antimicrobi...

Systematic substitutions at BLIP position 50 result in changes in binding specificity for class A β-lactamases

The production of β-lactamases by bacteria is the most common mechanism of resistance to the widely prescribed β-lactam antibiotics. β-lactamase inhibitory protein (BLIP) competitively inhibits class A β-lacta...

Copper chelation and interleukin-6 proinflammatory cytokine effects on expression of different proteins involved in iron metabolism in HepG2 cell line

In vertebrates, there is an intimate relationship between copper and iron homeostasis. Copper deficiency, which leads to a defect in ceruloplasmin enzymatic activity, has a strong effect on iron homeostasis re...

Knockdown of GGCT inhibits cell proliferation and induces late apoptosis in human gastric cancer

Gamma glutamylcyclotransferase (GGCT) has been proved to be involved in various cancers, but the biological function of GGCT in gastric cancer is still largely unknown.

Identification of replication-dependent and replication-independent linker histone complexes: Tpr specifically promotes replication-dependent linker histone stability

There are 11 variants of linker histone H1 in mammalian cells. Beyond their shared abilities to stabilize and condense chromatin, the H1 variants have been found to have non-redundant functions, the mechanisms...

Avoiding false discovery in biomarker research

Human tyrosine-protein phosphatase non-receptor type substrate 1α (SIRPA) is a surface marker identified in cardiomyocytes differentiated from human embryonic stem cells. Our objective was to determine if circ...

Computational studies of human class V alcohol dehydrogenase - the odd sibling

All known attempts to isolate and characterize mammalian class V alcohol dehydrogenase (class V ADH), a member of the large ADH protein family, at the protein level have failed. This indicates that the class V...

Effect of mutations to amino acid A301 and F361 in thermostability and catalytic activity of the β-galactosidase from Bacillus subtilis VTCC-DVN-12-01

Beta-galactosidase (EC 3.2.1.23), a commercially important enzyme, catalyses the hydrolysis of β-1,3- and β-1,4-galactosyl bonds of polymer or oligosaccharidesas well as transglycosylation of β-galactopyranosi...

Sustained activation of mTORC1 in macrophages increases AMPKα-dependent autophagy to maintain cellular homeostasis

The mechanistic target of rapamycin complex 1 (mTORC1) is a well-conserved serine/threonine protein kinase that controls autophagy as well as many other processes such as protein synthesis, cell growth, and me...

Auto-thiophosphorylation activity of Src tyrosine kinase

Intermolecular autophosphorylation at Tyr416 is a conserved mechanism of activation among the members of the Src family of nonreceptor tyrosine kinases. Like several other tyrosine kinases, Src can catalyze th...

Effects of protonation on the hydrolysis of triphosphate in vacuum and the implications for catalysis by nucleotide hydrolyzing enzymes

Nucleoside triphosphate (NTP) hydrolysis is a key reaction in biology. It involves breaking two very stable bonds (one P–O bond and one O–H bond of water), in either a concurrent or a sequential way. Here, we ...

Molecular characterization of protein kinase C delta (PKCδ)-Smac interactions

Protein kinase C δ (PKCδ) is known to be an important regulator of apoptosis, having mainly pro- but also anti-apoptotic effects depending on context. In a previous study, we found that PKCδ interacts with the...

Identification and characterization of the novel nuclease activity of human phospholipid scramblase 1

Human phospholipid scramblase 1 (hPLSCR1) was initially identified as a Ca 2+ dependent phospholipid translocator involved in disrupting membrane asymmetry. Recent reports revealed that hPLSCR1 acts as a multifunc...

Tubulin is a molecular target of the Wnt-activating chemical probe

In drug discovery research, cell-based phenotypic screening is an essential method for obtaining potential drug candidates. Revealing the mechanism of action is a key step on the path to drug discovery. Howeve...

Altered activity patterns of transcription factors induced by endoplasmic reticulum stress

The endoplasmic-reticulum (ER) responds to the burden of unfolded proteins in its lumen by activating intracellular signal transduction pathways, also known as the unfolded protein response (UPR). Many signal ...

Conserved motif VIII of murine DNA methyltransferase Dnmt3a is essential for methylation activity

Dnmt3a is a DNA methyltransferase that establishes de novo DNA methylation in mammals. The structure of the Dnmt3a C-terminal domain is similar to the bacterial M. HhaI enzyme, a well-studied prokaryotic DNA meth...

Linalool isomerase, a membrane-anchored enzyme in the anaerobic monoterpene degradation in Thauera linaloolentis 47Lol

Thauera linaloolentis 47Lol uses the tertiary monoterpene alcohol ( R,S )-linalool as sole carbon and energy source under denitrifying conditions. The conversion of linalool to geraniol ...

1,2-Dichlorobenzene affects the formation of the phosphoenzyme stage during the catalytic cycle of the Ca 2+ -ATPase from sarcoplasmic reticulum

1,2-Dichlorobenzene (1,2-DCB) is a benzene-derived molecule with two Cl atoms that is commonly utilized in the synthesis of pesticides. 1,2-DCB can be absorbed by living creatures and its effects on naturally-...

Substrate specificity and function of acetylpolyamine amidohydrolases from Pseudomonas aeruginosa

Pseudomonas aeruginosa , a Gram-negative, aerobic coccobacillus bacterium is an opportunistic human pathogen and worldwide the fourth most common cause of hospital-acquired infections w...

Erratum to: Purification and characterization of a cytochrome c with novel caspase-3 activation activity from the pathogenic fungus Rhizopus arrhizus

The original article was published in BMC Biochemistry 2015 16 :21

BMC Biochemistry Reviewer Acknowledgement, 2015

The editors of BMC Biochemistry would like to thank all our reviewers who have contributed their time to the journal in Volume 16 (2015).

BMC Biochemistry

ISSN: 1471-2091

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Explore a collection of the most read and most cited articles making an impact in the Journal of Biochemistry  published within the past two years. This collection will be continuously updated with the journal's leading articles so be sure to revisit periodically to see what is being read and cited.

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Biochemistry

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Biochemistry is the study of chemical processes within and relating to living organisms. Biochemical processes give rise to the complexity of life. Biochemistry can be divided in three fields; molecular genetics, protein science and metabolism. Over the last decades of the 20th century, biochemistry has through these three disciplines become successful at explaining living processes. Almost all areas of the life sciences, like botany, medicine and genetics are being uncovered and developed by biochemical methodology and research. Biochemistry focuses on understanding how biological molecules give rise to the processes that occur within living cells and between cells, which in turn relates greatly to the study and understanding of tissues, organs, and organism structure and function.

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Thumbnail: An enzyme binding site that would normally bind substrate can alternatively bind a competitive inhibitor, preventing substrate access. Dihydrofolate reductase is inhibited by methotrexate which prevents binding of its substrate, folic acid. Binding site in blue, inhibitor in green, and substrate in black (PDB: 4QI9​). (CC BY 4.0;  Thomas Shafee ).

90 Biochemistry Essay Topic Ideas & Examples

🏆 best biochemistry topic ideas & essay examples, 🎓 interesting topics to write about biochemistry, ⭐ simple & easy biochemistry essay titles, ❓ biochemistry essay questions.

  • How Biochemical Conditions and Brain Activity are Linked to Crime Studies have shown that areas with high rates of homicide and other forms of violence had a lot of lead in the air.
  • Biochemical Metabolism: Foreign DNA Molecule The virtual gel should show the band pattern that would result from incubating the plasmid with restriction enzymes as indicated below. We will write a custom essay specifically for you by our professional experts 808 writers online Learn More
  • Biochemical Oxygen Demand Measurement The Population of the aquatic microbes is directly correlated to the amount dissolved organic compound in water; that is to say, the higher the amount of organic compounds the larger the microbe population.
  • COVID-19 Vaccines’ Biochemical and Technological Basis Various types of vaccines have been developed in the United States and Europe to mitigate the effects of the coronavirus disease pandemic.
  • Water and Its Role in Biochemical Processes The goal of this paper is to discuss the chemical properties of water that are most important for life on Earth.
  • Common Biochemical Cycles Carbon is also an important element for the living organisms; hence the carbon cycle which is a gaseous cycle takes place to recycle the carbon and make it available for the living organisms.
  • The Teenage Experience and Biochemical Changes It is most likely that for teenagers of all generations, the strive to be independent and free will be relevant in one shape or form.
  • Biochemical and Technological Basis Behind COVID Vaccines The background image represents the virus model where the blue color denotes the surface area of the virus and the red color symbolizing the spike protein.
  • “Biochemistry of Love” by Carter & Porges The key concepts explored in the chapter include the role of oxytocin and vasopressin in the creation of emotional bonds. The other two notable concepts described in the chapter are the impact of love on […]
  • Spectrophotometry Used in Biochemical Settings The work of a spectrophotometer is based on this law to calculate the amount of light, its absorption, and concentration. Spectrophotometry is necessary to demonstrate how non-destructive methods help check the condition of the water, […]
  • The Universal Nature of Biochemistry If the power between the two atoms is the same they share the electrons and form a covalent bond, but if one atom’s power exceeds the other, then one loses the electron or electrons to […]
  • Biochemical Oxygen Demand Measurement The essence of the method of measuring BOD is to establish the concentration of molecular oxygen in the water sample immediately after the selection and after incubation periods of the sample.
  • Green Fluorescent Protein – Applications in Biochemistry While undertaking the isolation, the authors noted in their study that one of the distinctive properties of the Aequoria aequoria is that it had the ability to emit a greening luminescence.
  • Musical Exposure and Its Effect on Biochemical Changes Last, to policymakers and nursing practitioners, the effect of specific music types on various biochemical messengers lays solid ground for understanding music’s function in physiological mechanisms.
  • Vitamin B6: Biochemical Overview In order to maintain the proper percentage of Vitamin B6 in the patient’s body, it is imperative that the dietary allowances of the vitamin should be in direct proportion to the patient’s age; more to […]
  • Biochemistry: Protein Translocation Types & Forms The occurrence of this channel occurs due to the existence of a preserved heteromeric membrane protein complex. The result of this is forward translocation movement.
  • Natural Biochemical Cycles in the Ecosystem Water moves through the environment through various processes such as evaporation and transpiration from the vegetation into the environment. This leads to the accumulation of these elements in the environment.
  • Michael Smith: Nobel Prize-Winning Biochemist In the late 1980s, he helped found the Biotechnology Laboratory located at the University of British Columbia. Since he was a firm believer in genomic research, he accepted the appointment by Victor Ling to become […]
  • Biochemistry and Volunteer Work In particular, I was the volunteer at ophthalmology center to work with patients and learn more about physiology and biochemistry of the eye and its parts.
  • Biochemistry Dogmas and Their Impacts on Biotechnology Unlike in the past, people have seen the importance of studying life sciences, and with the support from private and public sectors, the number of students enrolling in life science courses is on the rise. […]
  • Biochemistry of Metabolism in Health & Disease
  • Advances in Biochemistry in Health and Disease
  • Amplifying Biochemistry Concepts With Content-Rich Music
  • Scope and Application of Biochemistry
  • Biochemistry: Biosynthetic and Energy Metabolism and Its Regulation
  • 10 Reasons Why Biochemistry Is Important
  • Industrial Applications of a New Biochemical Technology
  • The Importance of Biochemistry in Medical Science
  • Biochemistry and Its Application in the Discovery and Development of a New Drug
  • Chemistry and Biochemistry of Amino Acids, Peptides, and Proteins
  • Example of Biochemistry in Daily Life
  • Applications of Biochemistry in Daily Life
  • The Biochemical Diagnosis of Heart Disease
  • Biochemistry for Sport and Exercise Metabolism
  • Introduction to Biochemical Pharmacology and Drug Discovery
  • Applications of Biochemistry and Molecular Sciences Research
  • The Biochemistry of Metabolism
  • Discovering Functional Relationships: Biochemistry Versus Genetics
  • Biochemical Basis of Dna Replication Fidelity
  • Physicochemical and Biochemical Aspects of Pharmacology
  • General Introduction to Biochemistry and Its Applications
  • Which Is Better, Biomedical Science, or Biochemistry?
  • The Use of Biochemistry Within Biotechnology
  • Fat Cell Filling, Ketogenic Diet, and the History of Biochemistry
  • Principles of Biological Sciences: Botany, Biochemistry, Biological Sciences
  • Biochemical Aspects of Lipid Storage and Utilization in Animals
  • What Is the Importance of Biochemistry in Public Health
  • Applications and Trends in Systems Biology in Biochemistry
  • The Role of Clinical Biochemistry in Community Health
  • Problem Solving in Biochemistry: A Practical Approach
  • The Biochemistry and Technology of Tea Manufacture
  • Biochemical Properties of Human D-Amino Acid Oxidase
  • Introduction to Amino Acids in MCAT Biochemistry
  • Stereochemistry and Its Application in Biochemistry
  • Metabolism in Motion: Engaging Biochemistry Students With Animation
  • The Biochemical System Controlling the Effects of Cannabis
  • Recent Advances in Biochemistry
  • Tryptophan Biochemistry: Structural, Nutritional, Metabolic, and Medical Aspects in Humans
  • Biochemical Mechanisms of Medicine
  • Difference Between Biology and Biochemistry
  • What Is the Biochemistry Used For?
  • Which Country Is Most Famous for Its Biochemists?
  • What Are the Fields of Biochemistry?
  • Is Biochemistry a Hard Major?
  • What Are the Branches of Biochemistry?
  • Do Biochemists Make Medicine?
  • What Is the Main Study of Biochemistry?
  • What Is the Highest Paid Job in Biochemistry?
  • Why Do Nurses Need to Study Biochemistry?
  • What Careers Would Fall Under Biochemistry?
  • Can a Biochemist Become a Nurse or a Doctor?
  • What Tests Are in Biochemistry?
  • Why Is It Important to Learn Biochemistry?
  • What Is Common and Different Between Biochemistry and Medicine?
  • How Are the Principles of Biochemistry Applied in Practice?
  • What Is the Role of Math in Biochemistry?
  • How Can We Apply Biochemistry in Daily Life?
  • How Long Does It Take To Get a Biochemist Degree?
  • Which Branch of Biochemistry Would You Choose to Study?
  • Is It Possible to Make a Career in Biochemistry?
  • Who Is the Most Famous Biochemist?
  • What Subjects Are Taught in Biochemistry?
  • What Is the Best College for a Biochemist?
  • Who Is the Father of Biochemistry?
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  • Is Biochemistry More Biology or Chemistry?
  • What Is an Example of Biochemistry?
  • What Branch of Biology Is Biochemistry?
  • Who First Discovered Biochemistry?
  • What Does a Biochemist Do in a Hospital?
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202 Interesting Biochemistry Research Topics For Any Taste

Biochemistry Research Paper Topics

Science-related courses are not everyone’s favorite. The few passionate and enthusiastic minds that delve into this field can also attest to its technical nature. With the intensive research, one has to perform biochemistry; it is no secret that professional assistance is inevitable. We have collated a list of the crème de la crème biochemistry research paper topics for your inspiration. Keep reading this post to the end to identify them and use one of them in your project today!or buy thesis online

What Are Biochemistry Research Topics?

How to find biochemistry paper topics, easy biochemistry research topics list, interesting biochemistry topics, cool biochemistry topics for quality grades, popular ideas for biochemistry research projects, actual topics in biochemical research, good biochemistry science fair projects, hot topics in biochemistry, remarkable biochemistry project topics, topics that deal with various fields of biochemistry, current topics in biochemical research.

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Biochemistry is a science-related field with roots in chemistry and biology – deals with the organic chemistry of compounds and processes occurring in organisms. This field seeks to understand biology within the context of chemistry.

Therefore when we talk about biochemistry research topics, we are dealing with all the relevant aspects of biochemistry. Such issues tend to identify problems in this field and try to bring out working solutions or recommendations in the end. Like any other research topic, these also seek to explore researched and least researched areas of biochemistry and add knowledge to the field.

Although most college and university students perceive this to be a daunting task, it is the reverse of it all. Biochemistry is something that we apply in our everyday life, and thus we can easily find such topics. Nonetheless, here are some concrete places you can begin your search from:

The biochemistry books on your library shelf Reputable online sites that major in biochemistry Articles, journals, conference papers, and orations on biochemistry Latest news headlines Previous theses and research papers on biochemistry

With all these sources, you are as prepared as a soldier for battle. Nothing can stop you from writing biochemistry topics that will yield top grades. For those who wish to have something to start them off, here are 202 of the best biochemistry project topics!

  • How chemical processes related to living organisms
  • Discuss the process of information flow through biochemical signaling
  • How does chemical energy flow through metabolism?
  • The role of biochemical processes in giving rise to the complexity of life
  • How biochemistry transformed botany and genetics in the 20 th century
  • Various health dangers of sodium chloride in food
  • The role of laboratory technicians in advancing research in biochemistry
  • How developing nations are making strides in the field of biochemistry
  • The impact of coronavirus on the study and application of biochemistry
  • The efficacy of catalysts and enzymes in biological reactions
  • Phytochemical analysis of the various dyes sold in the market today
  • How bleaching agents interact with the human skin
  • Effects of technological advances on the study of biochemistry in universities
  • The rate of employment among biochemistry graduates in the United States
  • Discuss the chemical compositions of potassium permanganate
  • An evaluation of the chemical processes involved in the extraction of oxygen from the air
  • Effects of methanol on the human lungs and liver
  • Factors that necessitate the oxidation of various metals
  • How factories can contribute to the Standard Development Goals on clean energy
  • Chemical activities involved in the rusting of metals
  • Why does steel remain stainless as compared to other metals?
  • The role of practical experiments in understanding biochemistry
  • How to detect Mycobacterium Ulcerans on the human skin
  • Discuss the environmental reservoirs of most biological enzymes and catalysts
  • Risks associated with researching in a biochemistry lab
  • The effect of ecological conditions on extracts used in the lab
  • Evaluate the alkaloidal isolates of a plant
  • Analyze the various anti-inflammatory medicinal plants found in the tropical regions
  • Investigate the process of producing pro-inflammatory eicosanoids
  • What is the therapeutic action of anti-inflammatory medicinal plants?
  • The impact of herbal preparations on treating skin diseases
  • How to destabilize Lysozyme activity
  • The impact of various temperature ranges on enzyme activity
  • What is the role of alpha crystalline in a concentration?
  • Factors that necessitate insulin resistance in human bodies
  • Biochemistry experiments that have helped in treating cardiovascular diseases
  • What is the relationship between T2DM and a high level of hepcidin?
  • Factors that necessitate the regulation of iron homeostasis
  • Evaluate the pathogenesis of diabetes and its complications
  • The impact of maternal serum on pregnant women
  • How to determine the amount of protein in the urine
  • Discuss the release of placental toxic factors and their impact on blood circulation
  • Evaluate the toxicological effects of Desmodium Adscendens in rats
  • The impact of high doses of the freeze-dried extracts on biochemical reactions
  • How to preserve plant extracts for biochemical experiments
  • Discuss the various pathogenic risks associated with breast cancer
  • An analysis of the multi-factorial diseases among women in the United States
  • Biological factors that necessitate promoting tumor growth
  • Evaluate the role of immunoglobulin G receptors in the study of clinical malaria
  • How to determine the antigen-binding capabilities of the receptors
  • A biochemical perspective of the gene encoding process for receptors
  • Molecular methods of investigating variations in genes: A case study of PCR
  • Biological processes that cause the inflammation of the intestinal mucosa
  • The role of Rotaviruses in causing Acute gastroenteritis (AGE) among children
  • How iron Chelators affect the various bloodstream forms of Trypanosoma Brunei
  • Discuss how clinicians determine the effectiveness of a particular drug
  • Evaluate the emergence of drug resistance among pregnant mothers
  • Alternative forms of therapy to drug toxicity in humans
  • How iron Chelators deferoxamine exhibits itself in Trypanosoma Brunei
  • Factors that inhibit cell growth and interfere with the activity of iron-dependent enzymes
  • Discuss the vitro effects of phenolic acids
  • The impact of variant frequencies in biochemical reactions
  • Biochemical processes that may lead to severe coronary malfunctions
  • Genetic factors associated with variability in individuals
  • How do different people respond to various vaccines during the clinical trials stage
  • The method of initiating a new drug in a patient
  • Evaluate the biochemical properties of the coronavirus
  • The role of sewage sources and disposal points in contributing to the survival of pathogens
  • How to determine relative molecular weights in the lab
  • The susceptibility of bacteria to antibiotics
  • Compare and contrast herbal preparations and scientific research processes
  • How to isolate pathogens from various food sources
  • Discuss the efficacy of using the indicator bacteria strains
  • How electron microscopy helps in isolating viruses and bacteria
  • The interrelationship between cellular and molecular biology
  • Discuss the genetic models for understanding regulatory mechanisms for homeostasis
  • What are the tools that regulate the cell population?
  • How to deal with pathologic disorders: A case study of Osteoporosis
  • Biochemical inferences to metastatic bone disease
  • How to discover embryonic malformations in pregnant women
  • Factors that disrupt signaling pathways and transcription factor networks
  • Evaluate various bone tissue from humans and animals
  • A technological analysis of genetic and proteomic processes
  • Discuss the various strides made in vivo molecular imaging
  • The role of scanning and electron microscopy in biochemistry
  • Effects of high-resolution micro-computed tomography in determining the accuracy of biochemical experiments
  • How to detect defects in cell biology: A case of soft tissue sarcoma
  • Investigate the advancements made in cell growth regulation
  • Discuss the epigenetic and genetic regulation of oncogenes
  • Analyze the factors that regulate the cell cycle
  • How to control the segregation of chromosomes
  • Why scientists need to govern cell motility
  • Discuss the relationship between nuclear structure and chromatin structure
  • Explore how the nucleus organizes nucleic acid metabolism architecturally
  • How to determine the atomic matrix of an RNA
  • What causes the nuclear lamina to have interconnected structures?
  • Discuss the process of DNA replication in a laboratory
  • What makes the RNA transcription process a complex one?
  • How to package DNA into active or silenced chromatin
  • How changes in the RNA and DNA cause diseases such as cancer
  • Discuss the kinetic characterization of the homeostasis process
  • How to determine the structure of new clotting factors
  • Effects of platelets in the identification of genetic risk markers
  • Why enzymes are necessary for almost every aspect of biochemistry
  • Discuss the process of recognizing a substrate by an enzyme
  • Evaluate the quantitative and structural approach to the study of enzymes
  • How to determine if selenium contains enzymes
  • Analyze the co-factors and enzymes involved in the coagulation cascade
  • Why structural biology should be a core research discipline in colleges
  • Analyze the X-ray structures of iron-binding in proteins
  • Factors that lead to the clotting of blood in humans
  • What are the DNA-protein complexes that are necessary for replication?
  • Discuss the regulation mechanisms of the transcriptional process
  • The role of synthetase – tRNA complexes
  • Discuss the assembling and regulation procedures of the DNA replication fork
  • How a synthetase distinguishes among dozens of tRNA species
  • The process of repairing DNA double-strand breaks
  • What goes on in the RNA transcription process?
  • The necessity of recombination in predicting the stability of genomes
  • Discuss the molecular processes involved in carcinogenesis
  • How to design new anti-tumor agents
  • Experimental approaches to determining the instability of genomes
  • Discuss site-directed mutagenesis of protein components
  • Biochemical analysis of DNA synthesis
  • Evaluate the properties of eukaryotic RNA polymerases
  • The role of transcription factors in biochemistry
  • What goes on in ATP-dependent chromatin remodeling?
  • Discuss the various structural proteins that comprise the chromatin
  • How to regulate transcription initiation and elongation
  • Factors that affect post-transcriptional regulation of gene expression
  • How to determine the active sweet components of artificial sweeteners
  • A comparative analysis of serum calcium levels in geriatric men
  • How to extract nutrients from plants
  • Evaluate the nutritional profile of vegetables: A case of spinach
  • How to produce starch from cassava
  • Evaluate the phytochemical properties of soap
  • Factors that lead to microbial food spoilers
  • How to determine biochemical parameters in the laboratory
  • A critical examination of Escherichia Coli in fecal pollution
  • Discuss the chemical compositions of water near a lead industry
  • Physic-chemical properties of yams and arrowroots
  • The impact of supplementing the body with vitamins
  • Effects of having fluorides in drinking water on the teeth
  • The implication of acid rain to surrounding building structures
  • Discuss the process of methanol leaf extraction
  • The role of high-fat diets in causing obesity and heart diseases
  • Concepts of analytical biochemistry
  • Biotechnology and applied biochemistry
  • How to produce deodorants using pawpaw leaves
  • What causes the spontaneous flow of active polar gels?
  • Discuss gene encoding in sorghum and cassava
  • What causes destabilization in lysosomes?
  • Evaluate some of the physicochemical processes that occur in living organisms
  • Discuss the conditions that necessitate antibacterial activity of Thymus Vulgaris
  • What are the optimum conditions for aqueous and ethanol extracts?
  • How Cadmium affects humans and the surrounding environment
  • Evaluate the fungal pathogens associated with tomatoes spoilage
  • The role of taxonomic groupings in biochemistry
  • How to produce protease using Aspergillus Flavus
  • The process of extracting medicinal components of plants
  • Effects of ethanol in causing corrosion
  • The role of watermelon in fighting viral activities
  • Plant science and medicine
  • Structure of molecules
  • Chemicals responsible for the immune system
  • Cells accountable for body defense
  • Why are pathogens dangerous?
  • Energy release from bonds
  • Structure of organelles
  • How coordination occurs in various components of cells
  • How the conversion of glucose occurs
  • Process of heat generation
  • Chemical effects of diseases
  • Functions of bio elements
  • The study of respiration
  • How to extract energy from food
  • Compounds necessary for body growth and development
  • How to diagnose diseases using various biochemical procedures
  • Why plant sugars are necessary for the process of photosynthesis
  • How carbon dioxide enters the leaves through stomata
  • The role of mitochondria, nucleus, Golgi bodies, and endoplasmic reticulum in the study of cell biology
  • Discuss the functioning of various molecules of life
  • Discuss the role of food additives in changing the way bacteria grows and develops
  • How to determine mutation in the structure of the DNA of bacteria
  • Discuss the process of deciding on a pregnancy test through urine samples
  • How to detect potential genetic defects in the fetus
  • Discuss the chromosomal abnormalities that lead to Down syndrome
  • How the absence of enzymes in the body leads to metabolic disorders
  • How biochemists insert the gene for human insulin into bacteria during genetic engineering
  • The process of creating genetically identical organisms through cloning
  • Evaluate the procedure of replacing a disease-causing gene through gene therapy
  • Analyze the various properties and reactions of compounds in animals
  • How to utilize compounds for body growth and development
  • The study of plant biochemistry: A case study of respiration and Glycolysis
  • How the structure of molecules affect metabolic reactions
  • Describe the process of speeding up reactions by enzymes
  • Discuss how catabolism and anabolism lead to the breaking down of larger molecules
  • What are the various mechanisms of reactions that cause pollution?
  • What are some of the emerging ethical and legal trends in biochemistry?
  • How the study of biochemistry supports our understanding of diseases and health
  • Discuss the contribution of biochemistry to innovative information and technological revolution
  • The role of biochemistry in determining policies and legal standards: A case study of coronavirus

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Biochemistry Research Paper Topics

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  • Carbohydrate
  • Cholesterol
  • Fermentation
  • Human Genome Project
  • Nucleic acid
  • Photosynthesis
  • Respiration

Biochemists study the structure and properties of chemical compounds in the cells of living organisms and their role in regulating the chemical processes (collectively called metabolism) that are necessary to life. These chemical processes include transforming simple substances from food into more complex compounds for use by the body, or breaking down complex compounds in food to produce energy. For example, amino acids obtained from food combine to form protein molecules, which are used for cell growth and tissue repair. One very important type of protein are enzymes, which cause chemical reactions in the body to proceed at a faster rate.

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Complex compounds in food, such as proteins, fats, and carbohydrates, are broken down into smaller molecules in the body to produce energy. Energy that is not needed immediately is stored for later use.

Biochemistry also involves the study of the chemical means by which genes influence heredity. (A gene is a molecule of DNA, or deoxyribonucleic acid, which is found in the nucleus of cells. Genes are responsible for carrying physical characteristics from parents to offspring.) A gene can be seen as a sequence of DNA that is coded for a specific protein molecule. These proteins determine specific physical traits (such as hair color, body shape, and height), body chemistry (such as blood type and metabolic functions), and some aspects of behavior and intelligence. Biochemists study the molecular basis of how genes are activated to make specific protein molecules.

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Teaching and Learning Medical Biochemistry: Perspectives from a Student and an Educator

Mehdi afshar.

Department of Biochemistry and Molecular Medicine, the George Washington University School of Medicine and Health Sciences, Room 547, Ross Hall, 2300 Eye Street NW, Washington, DC 20037 USA

Zhiyong Han

Advancement of medicine and that of biochemistry are inseparable, and much of modern medicine would not be practiced in the ways, as they are known today, without our understanding of how genetic, pathogenic and environmental factors affect the human body at the biochemical level. Thus, the importance of teaching medical students biochemistry is self-evident. Ironically, many medical students and practicing physicians consider learning biochemistry an unnecessary burden and that biochemistry has very little relevance to their daily practice of medicine [ 1 – 3 ]. Also, many students, especially those interested in fields such as primary care or psychiatry, also complain that there is too much anatomy in the preclinical curricula [ 1 ]. Thus, it seems that these students would prefer to selectively learn subject matters that they believe to be relevant to the medical specialties that they wish to acquire and practice in. Such utilitarian thinking, we believe, is in part responsible for the trend in medical curriculum that devaluates basic science and emphasizes apprenticeship experiences with clinical faculty [ 4 ].

Why do these medical students consider it unnecessary to learn biochemistry? What can educators do to convince them that learning biochemistry is important in their education? We have tried to answer these questions from the perspectives of M.A. (Mehdi Afshar), a fourth year medical student, and Z.H. (Zhiyong Han), a medical biochemistry educator. Based on our own experiences, we have considered and discussed four factors that we think partly explain why some medical students have unfavorable opinions about biochemistry (Table  1 ). We hope that our discussions could stimulate similar discussions among medical students and biochemistry educators elsewhere.

Factors negatively affecting medical students’ interest in biochemistry

Medical Biochemistry Needs to Present New Biochemistry Knowledge

A large number of the students admitted to medical schools already have undergraduate biochemistry education. But the experiences of MA show that much of his medical biochemistry materials are unnecessarily taught in ways and depth similar to those in his undergraduate biochemistry courses. We suggest that medical biochemistry should incorporate students’ previously learned knowledge with medical applications and fill in the gaps with new knowledge. For example, instead of re-teaching medical students to compare and contrast the structures of DNA and RNA and ask them to explain the difference between bases, one could discuss the biochemical basis of the “omics” that are profoundly changing medical research and medicine. Also, instead of re-teaching medical students the glycolysis pathway and asking them to memorize minute details of it, one could discuss the Warburg effect and why the glycolysis pathway serves to produce not only ATP, but more importantly molecules that are important for the metabolic requirements of cancer cells [ 5 ]. One could even discuss the rational for selecting certain glycolysis enzymes for the development of anti-cancer drugs [ 6 ]. This way of teaching is very likely to get students excited because it teaches them new knowledge and the applications of biochemistry knowledge to not only today’s medicine, but also future medicine.

Medical Students Need to Learn Medically Relevant Biochemistry

It puzzles students that medical biochemistry is generally presented outside the context of diseases and medicine. For example, medical students are still taught how to use the Gibbs free energy equation to calculate the free energy and equilibrium constant of reactions. We fail to see medical relevance of being able or unable to do so. Therefore, like others [ 7 ], we also suggest that educators need to focus on teaching medical biochemistry in ways that show medical relevance. To us, medically relevant biochemistry is one that gives students just enough information to be able to understand the basic mechanism of why a biochemical defect results in a disease and potential avenues of diagnosis and treatment. We admit that this is not an easy task, because so much biochemistry is about chemical formula, reaction mechanisms, pathways, and seemingly unrelated schemes that are too far detached from living human body functions, such as blood flow or heart beats; furthermore, because medical students take biochemistry prior to having any medical knowledge and hence it is extremely difficult for them to relate biochemistry to diseases by themselves as MA can tell from his personal experience. Nevertheless, it appears that most students can effectively learn and understand medical applications of biochemistry if the applications are presented to them in contextualized ways through uncomplicated medical cases. For example, students could easily see the biological importance and medical relevance of the V max and k m of glucokinase if they are shown real life cases of diabetes caused by mutations that alter the V max and k m of glucokinase [ 8 ].

Therefore, we suggest a way of teaching medical biochemistry. To do so, medical biochemistry educators need first to define core concepts and biochemical principles that teachers and students could review (or relearn) in a short period. The educator will then teach new concepts and medical applications of biochemistry, in an in-depth fashion, via a series of carefully designed PBL (problem-based learning) or CBL (case-based learning) modules [ 9 ]. The in-depth teaching should aim to (1) stimulate personal cognitive processes to first understand concepts and then connect concepts to construct knowledge structures, and (2) teach students to apply their knowledge to new situations and solve new problems. This way of teaching promotes lifelong learning, open inquiry, and critical thinking capability that physicians should have [ 10 , 11 ].

Alternatively, medical biochemistry could be taught in various way that integrate basic and clinical sciences that have been or are being adapted by medical schools worldwide [ 12 – 14 ]. Imagine the following scenario in an integrative curriculum. A biochemist starts the day by teaching students the biological roles of cholesterol, its synthesis, absorption, transportation, and disposition and how alterations in any of these processes change the laboratory values of the blood lipid test. The pathologist then continues by teaching the disease processes that result from dysregulation of the aforementioned events involving cholesterol. The nutritionist follows up by teaching dietary management of cholesterol-related disorders. Finally, the pharmacologist ends by discussing various treatment options and potential for future therapies. This integrative teaching allows students to see cholesterol metabolism in relationship to diseases and medicine from different perspectives without any delay.

Teaching of Medical Biochemistry Should Not Revolve Around Board Relevance

Some students seem to like the idea of learning just “board examination relevant” materials. As such, they simply want biochemistry to be presented to them in bullet points format that shows “key words connections” that are easy to recall during board examinations. This is a bad idea. Since board examinations assess a physician’s minimum competencies, we should not set the bar to the height of minimum competencies and limit ourselves to teaching and learning just a minimal amount of materials for passing examinations. We believe, for example, that it is not enough that physicians prescribe nucleoside analog-derived drugs, such as AZT, to treat HIV/AIDs—they should be able to articulate the biochemistry underlining the action mechanisms of these drugs. What we do not want is to produce physicians who can pass the board examinations with knowledge deficiencies and who are unable to critically read and understand the sciences in the articles published in medical journals, such as the Journal of Clinical Investigation , The Lancet , or the New England Journal of Medicine .

We Must Minimize Rote Memorization of Materials and Make Information Stick

Needless to say, students can attest that they have to memorize a huge amount of biochemistry materials. However, rote memorization is not synonymous to learning and understanding of the materials and produces learning fatigue. In the era of using pocket devices to instantly gain access to ubiquitous information, we should stop asking students to memorize a vast amount of details, such as the minute details in the metabolic pathways, as long as it does not reduce the quality of educational outcome. Instead, we should teach students how to conceptualize metabolic pathways with an emphasis on the biological roles of metabolic pathways and their interconnection in the context of physiology and diseases. Then, we test the students’ understanding of the metabolic pathways and their interconnection by assessing whether they know where and what information to look for in the metabolic pathway charts when solving problems. Thus, it is best, for example, if a student knows how to diagnose a metabolic defect that causes methymalonic acidemia using a metabolic pathway reference. This idea was proposed by Professor Edward J. Wood 23 years ago, and he suggested then that it would be better if we stop “asking students to remember detailed information [of a metabolic pathway], to reproduce it accurately under stressful, time-limited [examinations] conditions, and in competition with their peers [ 15 ].”

Equally important, biochemistry needs to be taught in ways that stick with students—the stickier the better—to reduce rote memorization. There are many ways to make things stick [ 16 ], and it requires personalities, presentation styles, use of vivid and sticky examples, clarity, and even something that shocks [ 16 ]. For example, the shocking case of a 66-year-old “man” who turns out to be genetically a woman with Turner’s syndrome plus virilising 21-hydroxylase deficiency should allow students to visually understand the function and biological significance of the 21-hydroxlyase in the context of steroid synthesis [ 17 ]. Stories like this one should grab students’ attention, induce students’ curiosity and interest, unfold medical/biochemical investigative events before students, vividly relate biochemistry to medicine, and will stick!

In summary, medical biochemistry needs to highlight how biochemistry applies to medicine, minimizes rote memorization, and stick with students. The best outcome should be one that highlights the connection between medical biochemistry and its clinical applications. The ultimate goal of medical biochemistry, in our opinion, should be to provide students with fundamental biochemistry concepts and principles that serve as a knowledge foundation enabling them to better study and understand the complexities of diseases and medicine. Teaching biochemistry concepts and principles to students should be aimed at helping the students to become scientifically literate so that they will gain the ability to become independent learners in the future, and be able to critically read and understand biomedical literatures, participate in biomedical research projects, and evaluate claims of efficacy and safety of new therapeutic strategies. This will help students become the best doctors that they can be, and provides the best care for patients throughout their careers.

Acknowledgments

We thank Dr. Rakesh Kumar for bringing us together to discuss issues concerning teaching and learning biochemistry in the medical school. ZH thanks Drs. Mark S. Elliott and Glen A. Walker for many stimulating discussions about teaching medical biochemistry.

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Top 80 Biochemistry Research Topics

Biochemistry research topics

Biochemistry is simply the study of life. Enrolling in a biochemistry course requires you to extensively study the biological and chemical functions of living organisms, which equips you with the best biochemistry research topic ideas as you progress with your study. But again, all this is not a walk in the park.

Are you a student looking forward to writing a research paper that your examiners or teachers would be happy to read and award you an excellent score? We’ve shared the biochemistry research topics list across various subjects in this article to help you know what the best topics look like. Be sure to go through this piece in its entirety.

Biochemistry Research for Students (Preparation and Ideas)

In most universities, a senior biochemistry research project is a must before you complete your biochemistry coursework. But that’s not all. At various points of your study, whether studying pure biochemistry or related courses like molecular biology, examiners will require you to write a biochemistry research essay, term paper, or thesis.

To show you are focused on your studies and understand biochemistry better, come up with interesting biochemistry topics, and structure your work perfectly. A biochemistry research paper should capture the examiner’s interest and allow you to prove the content extensively. Ensure the topic is also manageable and compliant with your research environment.

With that, you will get things done in the nick of time without compromising on the quality of your work. No examiner will have a problem with a research essay, assignment, or dissertation that has sense and follows the academic rules. In fact, well-proposed biochemistry research ideas attract lots of funding, and you might be lucky to have a breakthrough in your early career.

Most of the biochemistry topics for research ideas revolve around:

  • Structure and functioning of various body cells.
  • Biochemical reactions in humans and plants.
  • Heredity in living organisms.
  • Pharmacology and pharmacognosy.
  • DNA, RNA, and proteins in plants and animals.
  • Molecular nature of all the bio-molecules.
  • Micro-organisms.
  • Enzymes, bioenergetics and thermodynamics.

Interesting Topics in Biochemistry

Many students struggle to think of interesting topics for their courses, and that’s not exceptional in biochemistry. You’ll notice that most of the topics’ interests depend on what a student is passionate about. Here are some interesting biochemistry topics to check out:

  • Understanding the role of microbial itaconic acid production during fungi synthesis.
  • Membrane biology and ion transport process in the innate immune response.
  • Inhibition of sprouty2 in periodontal ligament cells and their extensive biological effects.
  • Peptide and protein structure in membranes: what role do they play in cell membrane formation?
  • Understanding the evolution of microbial infections and related effects in the existing surroundings.
  • The role of B cell receptors in infections and vaccine production.
  • Human health and bacteriophages of different kinds: How the two correlate.
  • AN analysis of biofilm formation: From therapeutics to molecular mechanisms, and everything in between.
  • Close comparison and analysis of nucleic acids (DNA and RNA) in mice and humans.
  • Understanding the relationship between NDR1/2 and mob-based proteins in cell cycle damage signaling.

Biochemistry Topics for Presentation

If you have an incoming presentation, you must pick your topics carefully. Presentations can be a challenge at times. While some individuals in the audience might not have extensive knowledge of the subject, you must have a detailed understanding of your topic to score better. Here are some of the best biochemistry presentation topics:

  • A stepwise understanding of the human immune system and the role played in cell regeneration during an infection.
  • A deep analysis of different plant pathologies with a focus on phytochemicals present and their roles.
  • A look at the biochemical process that leads to apoptosis in patients with stage IV breast cancer.
  • Understanding the close relationship in terms of practice in biochemistry and pathological psychiatry.
  • Understanding different types of polymorphism and how they affect the DNA of human beings.
  • How hormone formation in children is dependent on the environment and child’s health condition.
  • The role of human cloning in the production and consumption of various types of vaccines.
  • The relationship between human molecular adaptation and diet: Does diet play a role?
  • Understanding how biological processes are dependent on the functioning of the human central nervous system.
  • Comparison of mice and human circulatory system: Functioning, susceptibility, capacity, and features.

Hot Topics in Biochemistry

Biochemistry has a vast range of hot topics to explore. Since you might not have the chance to write about everything concerning the course, our suggestions narrow your search efforts. Take a look at some of the hot topics in biochemistry below:

  • How professional breast cancer detection and screening is changing the lives of university students.
  • The revolution of tissue clearing techniques for optical microscopy as witnessed for the past five years.
  • Clinical features of acute copper sulfate poisoning and role of biochemistry in management interventions.
  • The role of malt in various beer quality and effects on beer stability: Industrial biochemistry of beer making.
  • Solid and liquid-state fermentation in the production of biochemical supplements for human and animal consumption.
  • Controlled mixed fermentation as witnessed in pharmaceutical product making over the years and the new normal.
  • The roles of polyphosphate on the virulence of Erwina caratovora bacteria in a range of plants.
  • An extensive comparison of the significant aspects of biochemical studies at the college and university level in the last half-century.
  • Analysis of molecular genetics and its close relationship with muscular dystrophy in men and women.
  • Supporting evidence on children’s growth and development in countries using genetically modified organisms feeding products.

Project Topics for Biochemistry

Would you like to write a project topic on biochemistry that might change the world? Then you need to work on something that excites and allows you to develop a deep interest in your course. Project topics in biochemistry are not complicated, provided you are willing to challenge yourself and learn. Here are some of them for inspiration.

  • Breast cancer and obesity in women of younger age; the clinical analysis from a biochemistry perspective.
  • Understanding biochemistry of biomolecules and amino acids and their clinical application in drugs and supplement making.
  • The future of artificial intelligence and its relevance to biochemistry: The gradual changes witnessed over the last four years.
  • Understanding stability of 81 analytes in human blood, serum, and plasma during diagnosis in clinical biochemistry set up.
  • History of clinical biochemistry and why it matters to modern human medicine.
  • Transforming the liver function tests with new biochemistry diagnostic simple tools; how to make things result-oriented
  • The role of clinical biochemistry in helping us understand the human immune system.
  • Understanding and redefining the role of the human bones: How biochemistry transforms the narrative on human bones predisposition.
  • A detailed clinical biochemistry analysis during pregnancy: tests associated with pregnancies and early child development.
  • The rise of clinical biochemistry in the present times, from introductory chemistry of life to foundation on infections and disease interventions.

Biochemistry Research Topics for Undergraduates

Choosing an ideal biochemistry research topic as an undergraduate student taking biochemistry at the college or university level can be a complex process for you. We have ten topics that you can choose to base your research on. Let’s take a look at the best biochemistry research topics for undergraduates’ topics:

  • Microbial food spoilage, resulting disorders, and the best biochemistry control approach to leverage.
  • Comparative examination of serum calcium level among males using biochemistry testing techniques.
  • Phytochemical analysis of specific tomato products available in the market for public health safety.
  • The oxidative stress status of mice fed on oil bean seed meal and show the same applies to biochemical processes in humans.
  • How biochemical production of top-quality bar soaps compares with most detergents you see in the market today.
  • What are the health dangers associated with lead in water consumed in most universities?
  • Critical analysis of Pterocarpus mildbreadii (oha) seed: A detailed phytochemical review.
  • How to use biochemistry synthesis pathways to create a compound that prevents reactions from taking place.
  • Evaluation of bacteria components produced using pure starter culture in a biochemistry culture laboratory setup.
  • What’s the bacteriological quality of meat products in most butcheries in town?

MCAT Biochemistry Topics

You must always take your Medical College Admission Test seriously if you want to get a chance to join your favorite medical school. The test gives you a chance to show that you’re ready to handle the program and maintain an excellent performance throughout. Since you’re looking to get admission, here are the best MCAT biochemistry topics you might want to consider:

  • Application of mathematical concepts and techniques in biochemistry and their role in general medicine.
  • How catabolic and anabolic enzyme reactions contribute to cell functionality: Data-based enzymatic reasoning and graphical representations.
  • Chemical and physical foundations of biological systems that help us appreciate human anatomy.
  • How critical analysis and reasoning skills acquired in biochemistry play a significant role in medical schools.
  • How multiple biosynthetic pathways like the citric acid cycle and glycolysis influence human health and functionality?
  • A look at the psychological, social, and biological foundations of behaviors in relation to human biomolecules.
  • Understanding the biochemical basis of human psychology.
  • Critical analysis of biochemistry study areas and how they transform medicine.
  • Understanding the relationship between Omega-3 fatty acids and blood glucose levels in adults.
  • How fruits and vegetables regulate blood sugar in patients with diabetes: Biochemical pathways and mechanisms.

Popular Biochemistry Research Paper Topics

As a student pursuing biochemistry, you should be aware of some topics to expect during your program. Luckily, a lot is happening in the biochemistry field, giving you a chance to explore the subject even better. Take your time and go through these popular biochemistry research paper topics we have suggested below.

  • How does chemical energy flow in human cells during metabolism?
  • Understanding the primary chemical processes and their close relationship to the functionality of living organisms.
  • How biotechnology and molecular biochemistry continues to transform genetics and botany in the modern world.
  • How has the Coronavirus impacted the study and application of biochemistry for the last one year?
  • How common bleaching agents react with human skin and biochemistry interventions that solve the matter once and for all.
  • How do laboratory and medical-based practical experiments help undergraduate students understand biochemistry better?
  • How can factories leverage biochemistry and help achieve the goal of clean energy in cities and congested towns?
  • What biochemical activities are involved in drug production and testing? Pharmaceutical quality assurance and control
  • Discussing and analyzing the chemical properties of carbohydrates in energy formulation.
  • What factors necessitate fatty acids beta-oxidation? Fatty acids as super fuel in the human bodies functioning.

Current Biochemistry Topics

There’s no better way to show that you’re a sharp and informed student than knowing what’s happening in the biochemistry academic and practical world. Knowing current biochemistry topics is one way to showcase your awareness. We have compiled this list to help you create a top-quality research paper. Here we go!

  • How do hydrocarbons in amino acids impact biochemical reactions when the human body gets subjected to medication?
  • Why biochemistry research is promising when it comes to developing the best methods of initiating new medications to patients.
  • Understanding the covid-19 vaccines chemical properties and reactions in adult men and women.
  • Explaining various reactions to vaccines in the trial stage and how biochemistry has helped achieve the desired vaccines effectiveness.
  • What are the roles of biochemically developed rotavirus vaccines in acute gastroenteritis among infants?
  • How to best preserve plant extracts meant for experiments in biochemistry? Plant biochemistry and biotechnology research.
  • The relationship between different types of brain cancer with radiation exposure and genetics.
  • Understanding measles among infants and the most effective biochemistry based vaccine remedy
  • The role of biochemistry in governing cell motility during various stages of development.
  • The role of microscopy, scanning, and serum medical examinations in biochemistry.

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Are you confused about the best biochemistry project topics to work on? The above topics are an ideal starting point. But completing your assignment with the huge workload that comes with biochemistry is a significant problem. Worry not because you can now get biochemistry writing help from us.

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210 Biochemistry Research Topics For Your Class

210 Biochemistry Research Topics

Biochemistry research topics demand practical experiments with samples and specimens that yield the desired results. Before approval, a title in this field must start with a proposal representing the typology that the study will eventually produce. Project coordinators or supervisors must screen the topics that students choose without exceptions. Therefore, topic ideas must arise from careful cross-examination of sample specimens and experiments that researchers have watched for some time.

What is Biochemistry?

As the name suggests, biochemistry is the fusion of chemistry and biology in living organisms. Nobody can overstate the essence of biochemistry because it explains the causes of illnesses in animals and humans. Also, biochemistry continues to help researchers and scientists determine how molecules like proteins and vitamins function within the body.

Writing excellent papers in the fields of biochemistry requires admirable knowledge and a good understanding of this scientific branch. Luckily, the internet has many resources with materials that students can research their topics. But students should select their topics carefully and structure their papers properly to impress educators to award them top grades.

Biochemistry Paper Outline

A good biochemistry paper comprises several sections that enable the audience to understand the topic and its information. Here’s is an outline of a quality biochemistry paper.

Title page : The title page comes first in a research paper, providing an overview of the study. This page should include the running head, paper title, student’s name and affiliations, and page number. Students should format this page depending on their writing style, whether MLA, APA, or Chicago. Intro : The introduction is the second section of a biochemistry research paper. And this part should have an abstract and an introduction. Nevertheless, this part places the work into context for the audience. It also tells the readers why the study is relevant. Literature review : In this section, the student examines the materials they consulted during research. A good paper comprises a comprehensive assessment to show that the author read several published works on the issue. It also shows why the current study is essential and different. Methodology : Here, the writer explains their methods to gather and analyze the information they convey to the audience. This section is essential because it enables the audience to evaluate the validity of the research. Researchers can use experiments, observation, case studies, and documentary methods in their research. Analysis and discussion : In this section, the writer conveys the results of their research work. They also expound on their methodology. This part can include tables and figures that are easy-to-understand and precise. Conclusion : This part of a biochemistry paper summarizes the research while suggesting further studies on the topic. Reference : This section lists the materials that the writer consulted during the research. Including a bibliography makes the work authentic.

College and university learners must pick interesting topics to enjoy working on their research projects. Without exciting topic ideas, learners can struggle to work on their papers from the beginning to the end. That’s why this article lists some of the best and popular topics in this scientific field. However, you should remember there is always a possibility to custom dissertation from our professional helpers team.

Remarkable Biochemistry Research Paper Topics

Maybe you’re looking for a topic that will leave the educator no option but to award you the best grade in your class. If so, consider the following ideas for your research paper.

  • Can watermelon help in the fight against viral activities?
  • Explain how ethanol causes corrosion
  • How scientists extract the medicinal components of a plant
  • Taxonomic groupings’ role in biochemistry
  • Investigating the fungal pathogens that science associates with tomato spoilage
  • The impact of Cadmium on humans and the environment
  • The optimum conditions for ethanol and aqueous extracts
  • How drinking water fluorides affect your teeth
  • How acid rain impacts building structures
  • The methanol leaf extraction process
  • How high-fat diets cause heart diseases and obesity
  • The analytical biochemistry concepts
  • Applied biochemistry and biotechnology- What’s the correlation?
  • How to use pawpaw leaves to produce deodorants
  • The active polar gels spontaneous flow and the causes
  • Analyzing gene encoding in cassava and sorghum
  • Destabilization’s causes in lysosomes
  • Evaluating physicochemical processes in living organisms
  • Investigating conditions that facilitate Thymus Vulgaris’ antibacterial activity

These are great topics that will impress your professor to award you a good grade. Nevertheless, prepare yourself to research any of these ideas extensively before writing.

Interesting Biochemistry Topics

When choosing a topic in this field, a vital consideration is ensuring that it’s exciting to hold the reader’s attention. Also, the learner should pick a topic they are interested in to write a winning piece. Here are exciting ideas to consider in biochemistry.

  • Comprehensive analysis of infectious diseases’ evolutionary biology
  • Photosynthesis and its functions
  • Reviewing plant disease management using modern technology
  • How oxytocin affects psychopathic disease treatment
  • Analyzing the factors causing genetic mutation
  • How addictive substances affect the human genes
  • Living organisms and their cell structures
  • The development of cellular technology
  • Gestation period and its function in mammals
  • Cellular biology functions in recognizing and identifying genetics
  • Studying chemical reactions in the body using hormones
  • Alzheimer’s disease and therapeutic advances in treating it
  • The regulation mechanisms of stem cell biology
  • Cancerous cells and their biology
  • Genetic mapping and linkage analysis
  • The nucleic acid structure
  • Coronavirus and epidemiology
  • Cellular membranes’ functions and their essence in life forms
  • Analyzing the capabilities of prokaryotic and eukaryotic cells
  • Studying the apoptosis significance in faulty cells’ growth
  • Understanding the role of microbial itaconic acid and the production of fungi synthesis
  • Analyzing MOBs and NDR1/2 relationship in signaling a defective cell cycle
  • Documenting and mapping morphogen signaling pathways and regulation of biological responses
  • Vaccines and diseases- Understanding B cell receptors targeting
  • Bacteriophages and human health
  • Microbial biofilm formation- Molecular mechanisms therapeutics
  • Comparing protein folding and design between humans and mice
  • Investigating the evolution of microbial diseases
  • The role of structural determinants of protein in human health
  • Analyzing ion transport and membrane biology in innate immune response
  • How protein-membrane structure and function affect drug distribution
  • Why is protein-membrane design so important?
  • Cellular basis and mapping biochemical glucose transport of the insulin action and resistance
  • Comprehending the role of peptide and protein structure in membranes
  • The essence of platelet function and dysfunction on injuries
  • Understanding Sprouty 2 inhibition impacts on periodontal ligament cells
  • How placental toxic factors’ release affects blood circulation
  • Determining the protein amount in urine
  • How maternal serum affects pregnant women
  • Evaluating diabetes’ pathogenesis and its impact
  • What necessitates iron homeostasis regulation?
  • The relationship between high hepcidin level and T2DM
  • How biochemistry experiments have facilitated cardiovascular illnesses treatment
  • Factors necessitating insulin resistance in the body
  • Ways to identify mycobacterium Ulcerans on the skin
  • Environmental reservoirs of biological catalysts and enzymes
  • The risks of biochemistry lab research
  • Ecological conditions’ impact on lab extracts
  • Evaluating alkaloidal isolates in plants
  • Analyzing anti-inflammatory medical plants in tropical regions
  • Investigating pro-inflammatory eicosanoids’ production
  • Anti-inflammatory medicinal plants- Understanding their therapeutic action
  • How herbal preparations affect skin disease treatment
  • Destabilizing the Lysozyme activity
  • How temperature ranges affect enzyme activity
  • Alpha crystalline role in a concentration

These are exciting topics to consider for a biochemistry paper. However, they require an extensive investigation to draft a winning essay.

Current Topics in Biochemical Research

Maybe you want to write about something latest. In that case, consider these current topic ideas.

  • Investigating the role of peptide and protein function in membranes
  • Analyzing the biological impact of periodontal ligament cells
  • Critical analysis of microbial diseases’ evolution
  • Understand the regulatory mechanisms in genetics
  • B cells receptors role in vaccines and diseases
  • The biology and pathology of cancer
  • What regulates the population of cells?
  • Factors that scientists associate with new drug initiation to a patient
  • Phenolic acids and their vitro effects
  • Evaluating the effects of maternal serum on women during pregnancy and children
  • Alkaloidal isolates effects of plants
  • Chemical composition effects of potassium permanganate
  • Preliminary investigation on Citrus Sinensis Seed and Coat screening
  • Metalloenzymes and metalloproteins- The contrast
  • Aspirin chemical quantity analysis
  • Exploring Polyphosphate role on Erwinia Caratovora Virulence
  • Reviewing the human genome mapping and its impact on disease prevention
  • Why information matters in predicting the protein dihedral angles
  • Central dogma exceptions
  • Investigating the functions and structure of amino acids
  • Why protein Kinase matters in cancer and drug resistance
  • Malignancies biology and skeletal complications
  • Studying cellular structure and function
  • Biology and cancer pathology
  • Biology and coagulation disease
  • Understanding physical biochemistry
  • Intestinal microbes- What is their role in human health and diseases
  • Developing and characterizing chemical compounds targeting colon, pancreatic, and lung cancers
  • Using microarray technology in describing P623 and P73 regulated genes in cancer
  • The genetics of cancer molecules: Understanding the genomics-based method for gene expression and association studies
  • Lipid metabolism in mitochondrial and metabolic diseases
  • Genetic regulatory and epigenetic mechanisms
  • Functional nucleic acid and protein interactions
  • Structural biology and enzymology
  • Understanding measles in infants and biochemistry-based vaccination
  • Biochemistry’s role in controlling cell motility in different developmental stages
  • Why scanning serum medical examinations and microscopy matter in biochemistry
  • How various brain cancers relate to genetics and radiation exposure
  • How to preserve plant extracts for biochemistry experiments
  • Biochemical-based rotavirus vaccines’ role in acute gastroenteritis in children
  • Explain trial stages vaccine reactions and the role of biochemistry in achieving the desired results
  • How amino acids hydrocarbons affect biochemical reactions after subjecting the human body to medication
  • The essence of biochemistry research in developing ways to initiate new treatments in patients
  • Understanding the chemical properties of the COVID-19 vaccines and reactions in males and females

Biochemistry research projects on these topics can help learners unearth the latest information in their study field. What’s more, students can use them to showcase their awareness and impress educators.

Cool Biochemistry Topics

Selecting a topic that you’re comfortable working with will simplify your project completion. Here are excellent biochemistry paper topics to consider for comfortable research and writing experience.

  • Immunoglobulin G Receptors and their role in a clinical malaria study
  • The effects and process of destabilizing Lysozyme activity
  • The flow of chemical energy through metabolism
  • Phosphates structure as the necessary synthesis from alcohol
  • Bacteria membranes and their dynamics
  • DNA synthesis complexities in the definition
  • Assessing the chemical quality in Aspirin production
  • A comprehensive investigation of hepatitis B prevalence
  • A review of Amyloid diseases
  • Muscular dystrophy and molecular genetics analysis
  • Analyzing the latest high blood pressure medications
  • How variant frequencies affect biochemical reactions
  • Explain the phenolic acids’ vitro effects
  • What inhibits cell growth while interfering with iron-dependent enzymes’ activity?
  • Explain ways to determine iron Chelators deferoxamine presence in Trypanosoma Brunei
  • Alternative therapy forms to drug toxicity
  • Evaluating drug resistance in pregnant women
  • How clinicians determine a drug’s effectiveness
  • The effects of iron Chelators on different Trypanosoma Brunei’s bloodstream forms
  • Explain the Rotaviruses’ role in causing acute gastroenteritis in children
  • Understanding the biological processes responsible for intestinal mucosa inflammation
  • Molecular ways to investigate gene variations
  • Evaluating the toxicological impacts of Desmodium Adscendens in mice
  • How high freeze-dried extracts affect biochemical reactions
  • Pathogenic risks that scientists associate with breast cancer
  • Analyzing the multi-factorial diseases among females
  • The biological factors promoting tumor growth
  • Evaluating the immunoglobulin G receptors’ role in a clinical malaria study
  • Determining the binding capabilities of the receptors’ antigen
  • Receptors’ gene encoding process- A biochemical perspective

These ideas can be excellent topics for biochemistry research papers. However, learners should spend sufficient time researching their ideas to develop winning papers.

Hot Topics in Biochemistry

Perhaps, you want to write about a hot issue in this academic field. In that case, this section has a burning idea that you can explore.

  • Non-enzymatic and enzymatic protein role
  • The Stability, interactions, and structure in protein
  • How effective is population health in improving aggregate health performance in emerging economies?
  • Is amyloid disease transmissible?
  • Describe protein quantification
  • Define frequency modulation and controlled signaling
  • The potential and challenges of recombinant spider silk and its implications in biomedical applications
  • The use of biomedical means by athletes seeking unfair advantage
  • How human genome mapping can affect society and medicine
  • Analyzing biochemistry advancements and their effects on new medications
  • Reviewing the reactions and structure of phosphates and esters and their synthesis
  • Purification and expression of proteins’ responses at different ENTH levels
  • Evidence for or against animal disease models and scientific values in seeking disease cures
  • Investigating B lymphocyte cell line and aggregation from temperature sensitivity and chicken
  • The role of polyphosphate on Erwinia caratovora’s virulence
  • Molecular functions and cellular dissection in the latest high blood pressure medications
  • Comparing biochemical studies over the last century
  • Analyzing DNA synthesis complexes in the definition
  • Analyzing molecular genetics in a single causative gene and muscular dystrophy
  • Investigating complex biochemical compounds’ revelations in the DNA mapping study
  • Detecting soft tissue sarcoma
  • How to determine new clotting factors’ structure
  • How to confirm the presence of enzymes in selenium
  • Ethanol chemical compositions and their impact on the human liver and lungs
  • Rusting metals and their chemical properties
  • Alpha-crystalline’s role in a concentration
  • Why iron homeostasis needs regulation
  • Investigating the RNA’s atomic matrix
  • What does RNA transcription involve?
  • Coagulation disease’s biology

These are excellent biochemistry project topics for learners at various study levels. Nevertheless, students must research them extensively before writing.

Topics for Biochemistry Science Fair Projects

Picking a science fair project title can be cumbersome because the task is more demanding than writing a research paper. Here are brilliant ideas to consider for this project.

  • An electrolysis experiment
  • How to grow and use bacteria
  • Separating compound mixtures and their impact
  • Impact soft and hard water
  • Exploring different ways to extinguish fires without water
  • How temperature affects various liquids and their density
  • The effects and role of ethanol in erosions
  • The importance and impact of salt on melting points
  • Evaluating gasoline properties
  • Investigating the structure of enzymes
  • Anti-tumor agents and their design
  • The forms of x-ray of iron-binding in protein
  • Biochemistry and the necessary enzymes
  • Detecting invisible spills using backlight
  • How ultraviolet radiation affects bacteria growth
  • Plants crossbreeding
  • How smock pollution can affect plants’ transpiration rates
  • The DNA-protein complexes and their role in replication
  • How Ph and minerals’ concentration affect water and soil samples
  • How sunspots affect weather patterns

These biochemistry project topics are great ideas for a science fair. Nevertheless, they require time, effort, and research to convey relevant and quality information.

Easy Biochemistry Research Topics List

Maybe you need a simple topic to write about and score the top grade quickly. If so, here’s a list of easy ideas to consider for your paper.

  • How eukaryotic and prokaryotic cells create energy
  • The role of sunlight as the cells’ energy source
  • Analyzing cell membranes and protection mechanisms in living cells
  • Why investigating defective cells impact is important
  • Studying genetic materials role in differentiating cells
  • Organisms’ structure and physiological properties
  • Understanding cell’s composition and its functions
  • How cancer affects the cell growth
  • Current trends in molecular biochemistry
  • The microtubules’ role in the nervous system
  • Protein biosynthesis mechanics

All these are easy topics for academic papers. However, they still require some research before writing.

Get Professional Homework Help Online

Having a topic alone may not be enough to draft a winning paper. You also need skills, experience, and time to write a good essay. Unfortunately, some learners lack what it takes to compose a brilliant piece. That’s why we offer our affordable thesis writing service .

Once you seek our help, our trusted expert will research your topic and write a high-quality paper. Thus, you will beat the submission deadline and score the top grade in your class. Our service is cheap, reliable, and professional. Many learners have used it to excel academically. Contact us for quality help with your biochemistry paper.

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Enzymes articles from across Nature Portfolio

Enzymes catalyze nearly all of the chemical reactions that occur in biological systems. Enzymes are generally proteins but also include catalytic DNA and catalytic RNA. As effective biological catalysts, enzymes work by lowering a reaction’s activation energy barrier, thereby increasing the rate of the reaction. They also improve the specificity of the reactions.

easy research paper biochemistry

LPS gets a fresh trim

Detection of intracellular lipolysaccharide (LPS) activates an immune response initiated by the non-canonical inflammasome. ATGL has now been identified as a negative regulator of this pathway that dampens inflammation by removing LPS’ acyl chains, preventing the activation of inflammatory caspases and cytokines.

  • Gemma Banister
  • Dave Boucher

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Latest Research and Reviews

easy research paper biochemistry

Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5 -related dyskinesia

The authors describe the structure of an adenylyl cyclase 5 and Gβγ complex, which potentially influences a neural signalling pathway modulating motor function. Mutations in the Gβγ binding site on AC5 are linked to heritable forms of dyskinesia.

  • Yu-Chen Yen
  • John J. G. Tesmer

easy research paper biochemistry

Reversible conjugation of a CBASS nucleotide cyclase regulates bacterial immune response to phage infection

The authors propose a model for the mechanism underlying how a phage defence system remains primed for infection but tightly controlled to prevent host toxicity.

  • Larissa Krüger
  • Laura Gaskell-Mew
  • Malcolm F. White

easy research paper biochemistry

The effect of curcumin and high-content eicosapentaenoic acid supplementations in type 2 diabetes mellitus patients: a double-blinded randomized clinical trial

  • Kimia Motlagh Asghari
  • Parviz Saleh
  • Maryam Hashemian

easy research paper biochemistry

Allosteric activation unveils protein-mass modulation of ATP phosphoribosyltransferase product release

ATP phosphoribosyltransferase is a multi-protein complex where the catalytic protein HisGS is allosterically regulated by the regulatory protein HisZ; however, the protein dynamics of HisGS in enzyme catalysis remain underexplored. Here, the authors investigate the catalytic effect of isotope-labeled HisGS, revealing that the catalytic rate of HisZ-activated HisGS decreases in a mass-dependent fashion at low temperatures, which correlates to product release.

  • Benjamin J. Read
  • John B. O. Mitchell
  • Rafael G. da Silva

easy research paper biochemistry

Anaerobic cryoEM protocols for air-sensitive nitrogenase proteins

It can be challenging to obtain meaningful and accurate structural information for air-sensitive proteins. This protocol describes the application of customized vacuum manifold and anaerobic chamber setups for the purification and cryo-electron microscopy analysis of air-sensitive nitrogenase enzymes.

  • Rebeccah A. Warmack
  • Belinda B. Wenke
  • Douglas C. Rees

easy research paper biochemistry

Architecture and regulation of filamentous human cystathionine beta-synthase

Cystathionine beta-synthase is a conserved essential enzyme of one-carbon metabolism. Here, the authors show that the enzyme oligomerises to form filaments that undergo conformational and morphological changes in response to its activator S -adenosyl- L -methionine, the global methyl donor.

  • Thomas J. McCorvie
  • Douglas Adamoski
  • Wyatt W. Yue

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easy research paper biochemistry

Biocatalytic polymer synthesis with β-amino acids

  • Jan-Stefan Völler

easy research paper biochemistry

Death pools

easy research paper biochemistry

Just how big is the ubiquitin system?

The modification of proteins with the small protein ubiquitin constitutes a Daedalian system of posttranslational modifications in every eukaryotic cell, which is often referred to as the ubiquitin code 1 . Here we consider the scale and complexity of the ubiquitin system in light of recent developments.

  • Bernhard C. Lechtenberg
  • David Komander

easy research paper biochemistry

Modes of PADing

Developing therapeutic agents that target the peptidylarginine deiminase PAD4 requires better understanding of the function of the enzyme. Isozyme-selective antibodies that alter PAD4 activity have been identified recently, revealing unique modes of action.

  • Masaki Unno

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    Here are excellent biochemistry paper topics to consider for comfortable research and writing experience. Immunoglobulin G Receptors and their role in a clinical malaria study. The effects and process of destabilizing Lysozyme activity. The flow of chemical energy through metabolism.

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