Detail of a painting depicting the landscape of New Mexico with mountains in the distance

Explore millions of high-quality primary sources and images from around the world, including artworks, maps, photographs, and more.

Explore migration issues through a variety of media types

  • Part of The Streets are Talking: Public Forms of Creative Expression from Around the World
  • Part of The Journal of Economic Perspectives, Vol. 34, No. 1 (Winter 2020)
  • Part of Cato Institute (Aug. 3, 2021)
  • Part of University of California Press
  • Part of Open: Smithsonian National Museum of African American History & Culture
  • Part of Indiana Journal of Global Legal Studies, Vol. 19, No. 1 (Winter 2012)
  • Part of R Street Institute (Nov. 1, 2020)
  • Part of Leuven University Press
  • Part of UN Secretary-General Papers: Ban Ki-moon (2007-2016)
  • Part of Perspectives on Terrorism, Vol. 12, No. 4 (August 2018)
  • Part of Leveraging Lives: Serbia and Illegal Tunisian Migration to Europe, Carnegie Endowment for International Peace (Mar. 1, 2023)
  • Part of UCL Press

Harness the power of visual materials—explore more than 3 million images now on JSTOR.

Enhance your scholarly research with underground newspapers, magazines, and journals.

Explore collections in the arts, sciences, and literature from the world’s leading museums, archives, and scholars.

A comprehensive bibliographic database of the world’s scholarly literature

The world’s largest collection of open access research papers, machine access to our vast unique full text corpus, core features, indexing the world’s repositories.

We serve the global network of repositories and journals

Comprehensive data coverage

We provide both metadata and full text access to our comprehensive collection through our APIs and Datasets

Powerful services

We create powerful services for researchers, universities, and industry

Cutting-edge solutions

We research and develop innovative data-driven and AI solutions

Committed to the POSI

Cost-free PIDs for your repository

OAI identifiers are unique identifiers minted cost-free by repositories. Ensure that your repository is correctly configured, enabling the CORE OAI Resolver to redirect your identifiers to your repository landing pages.

OAI IDs provide a cost-free option for assigning Persistent Identifiers (PIDs) to your repository records. Learn more.

Who we serve?

Enabling others to create new tools and innovate using a global comprehensive collection of research papers.

Companies

“ Our partnership with CORE will provide Turnitin with vast amounts of metadata and full texts that we can ... ” Show more

Gareth Malcolm, Content Partner Manager at Turnitin

Academic institutions.

Making research more discoverable, improving metadata quality, helping to meet and monitor open access compliance.

Academic institutions

“ CORE’s role in providing a unified search of repository content is a great tool for the researcher and ex... ” Show more

Nicola Dowson, Library Services Manager at Open University

Researchers & general public.

Tools to find, discover and explore the wealth of open access research. Free for everyone, forever.

Researchers & general public

“ With millions of research papers available across thousands of different systems, CORE provides an invalu... ” Show more

Jon Tennant, Rogue Paleontologist and Founder of the Open Science MOOC

Helping funders to analyse, audit and monitor open research and accelerate towards open science.

Funders

“ Aggregation plays an increasingly essential role in maximising the long-term benefits of open access, hel... ” Show more

Ben Johnson, Research Policy Adviser at Research England

Our services, access to raw data.

Create new and innovative solutions.

Content discovery

Find relevant research and make your research more visible.

Managing content

Manage how your research content is exposed to the world.

Companies using CORE

Gareth Malcolm

Gareth Malcolm

Content Partner Manager at Turnitin

Our partnership with CORE will provide Turnitin with vast amounts of metadata and full texts that we can utilise in our plagiarism detection software.

Academic institution using CORE

Kathleen Shearer

Executive Director of the Confederation of Open Access Repositories (COAR)

CORE has significantly assisted the academic institutions participating in our global network with their key mission, which is their scientific content exposure. In addition, CORE has helped our content administrators to showcase the real benefits of repositories via its added value services.

Partner projects

Ben Johnson

Ben Johnson

Research Policy Adviser

Aggregation plays an increasingly essential role in maximising the long-term benefits of open access, helping to turn the promise of a 'research commons' into a reality. The aggregation services that CORE provides therefore make a very valuable contribution to the evolving open access environment in the UK.

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Stand on the shoulders of giants

Google Scholar provides a simple way to broadly search for scholarly literature. From one place, you can search across many disciplines and sources: articles, theses, books, abstracts and court opinions, from academic publishers, professional societies, online repositories, universities and other web sites. Google Scholar helps you find relevant work across the world of scholarly research.

academic research databases

How are documents ranked?

Google Scholar aims to rank documents the way researchers do, weighing the full text of each document, where it was published, who it was written by, as well as how often and how recently it has been cited in other scholarly literature.

Features of Google Scholar

  • Search all scholarly literature from one convenient place
  • Explore related works, citations, authors, and publications
  • Locate the complete document through your library or on the web
  • Keep up with recent developments in any area of research
  • Check who's citing your publications, create a public author profile

academic research databases

Disclaimer: Legal opinions in Google Scholar are provided for informational purposes only and should not be relied on as a substitute for legal advice from a licensed lawyer. Google does not warrant that the information is complete or accurate.

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What is a Library Database?

A database is a collection of information resources organized to provide efficient retrieval. The collected information could be in any number of formats (electronic, printed, graphic, audio, statistical, combinations). With access to thousands of journals, newspapers, and popular magazines, how do you find the resources you need?

What's a Library Database?

Video from RMIT University Library, Melbourne, Australia

Database Suggestions

Here are some recommended databases for broad research.

  • A-Z Databases All databases accessible through Sacramento State can be found here.

Primary Sources

  • Statista A statistics portal that integrates thousands of diverse topics - consumer goods, finance, politics, and many more areas of interest - and provides exportable data and facts from a wide range of sources.
  • Statistical Abstract of the United States (ProQuest) Provides a wealth of statistics on the social, political and economic conditions of the United States. The database includes 1400+ individually indexed tables (with attached spreadsheets) and is both searchable and browsable. Coverage: 2013 - current year
  • ProQuest Global Newsstream (ProQuest) Formerly ProQuest Newsstand, this database enables users to search the most recent global news content, as well as archives back into the 1980s featuring content from newspapers, newswires, and news sites in full-text format. This product provides one of the largest collections of news from the US, Canada, Europe, Africa, Asia, Latin America, and Australia.
  • Sacramento Bee (NewsBank) Includes current and historic full-text articles in text and/or image form as well as full-page views of each issue of the Sacramento Bee. Coverage: 1857 - today To access cover-to-cover images of recent issues of the Sacramento Bee daily newspaper in a browsable format click here . Coverage: November 7, 2017 - today

Secondary Sources

  • Academic Search Complete (EBSCO) This multi-disciplinary database provides access to full-text articles from popular magazines and scholarly journals (including peer-reviewed) journals. Includes topics in social sciences, humanities, science, education, and most areas of academic study.
  • CQ Researcher (CQ Press) CQ Researcher, providing balanced research about current controversial issues of public interest, with full text articles from November 1991 to the present

Tertiary Resources

  • Oxford English Dictionary The Oxford English Dictionary is the accepted authority on the evolution of the English language over the last millennium. It is a guide to the meaning, history, and pronunciation of over half a million words, both present and past. It traces the usage of words through 2.5 million quotations from a wide range of international English language sources, from classic literature and specialist periodicals to film scripts and cookery books. The OED covers words from across the English-speaking world, from North America to South Africa, from Australia and New Zealand to the Caribbean. It also offers the best in etymological analysis, listings of variant spellings, and shows pronunciation using the International Phonetic Alphabet.
  • Gale Virtual Reference Library Gale Virtual Reference Library is a collection of encyclopedias, dictionaries, and other research materials covering wide range of disciplines that can be searched and read online.
  • Oxford Reference Online Premium This is a collection more than 134 language and subject dictionaries published by Oxford University Press. Together they cover a wide range of fields including Architecture, Biology, Business, classics, Computing, Environmental Science, Economics, English Language, Food and Nutrition, History, Law, Literature, Mathematics, Medicine, Military Science, Language, Folklore, Performing Arts, Philosophy, Physical Sciences, Political science, Religion, and Social Science. The Premium Collection offers all of the above, plus added functionality and more detailed information across a broad subject range from titles in the world-renowned Oxford Companions Series, to enhance the coverage already provided by the award-winning Core Collection.

Reading a Scholarly Article

This video from Kishwaukee College Library explains how to quickly evaluate an article in a database:

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Expos 20 | Problems of Meaning: Language, Literature, and Life

  • Subject Databases: Tools for Deep-Searching and Close-Looking
  • Problems of Meaning in Language, Literature, and Life
  • HOLLIS: Searching Panoramically Across Harvard's Discovery Space

Databases: Why Use Them?

Top picks for essay 3.

  • Generating Research Leads From What You Have in Hand
  • Getting around Paywalls on the Web
  • Citing Your Sources

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Research projects often require you to look close up at a body of research produced by scholars in a particular field.  This research is typically collected, codified, and made findable in a tool called a  subject database .

Every academic discipline has at least one subject database that's considered the disciplinary gold standard -- a reliable, (relatively) comprehensive, and accurate record of the books that scholars are publishing, and the ideas they're debating and discussing in important and influential journals. 

Databases are like lenses: they change what you see and how you see it -- and they offer you easy and efficient ways to bring your questions into sharper focus.

Philosophy 

Stanford encyclopedia of philosophy .

  • Excellent for overview essays written by recognized subject experts and prominent academics, and accompanied by bibliography leads. 

Oxford Bibliographies Online: Philosophy    Harvard Key  

  • Annotated reading lists curated by experts, regularly checked for their currency and updated when necessary, OBOs aim to be representative, not comprehensive -- of the most impactful scholarship that's been produced to date. 
  • An online databas of scholarship  maintained by philosophers themselves that collects, categorizes, and makes philosophy research findable.  Specially curated pages perhaps pertinent to course themes include Philosophy of Language (which identifies key works and key introductory texts); Philosophy of Literature ; and Literary Values .

LINGUISTICS 

Oxford bibliographies online: linguistics    harvard key , linguistics and language behavior abstracts   harvard key .

  • A database that identifies articles, books, and other scholarly materials on linguistics and its related fields. 

Psychology 

Oxford bibliographies online: language (psychology) , apa psycinfo    harvard key .

  • The most important database access to research on all aspects of psychology,

LITERATURE 

Johns hopkins guide to literary theory and criticism    harvard key .

  • A comprehensive survey of the the most important figures, schools, and movements in literary theory.

Oxford Bibliographies Online: Literary and Cultural Theory   Harvard Key 

Mla international bibliography     harvard key .

  • The gold standard database for topics related to literature in all languages, folklore, cultural studies, theory, and more. 

Multidisciplinary 

Google scholar.

Although it's not a Harvard Library "database,"  Google Scholar  is perfectly acceptable for most general forays into scholarship; its algorithms are excellent and do return relevant results.

One of the best ways to generate research leads with Scholar is to use it to follow  citation trails    when you have a known source -- a class reading, a book you've found on HOLLIS that looks promising, an article that's so "perfect" for a research project that you want to see if there's "more like it" out there, waiting to be discovered. 

For example: 

  • You can click on  cited by   to see which scholars picked up and used a research article/book in research. Just enter the title.
  • Big "cited by" lists can be whittled down by adding keywords and clicking on the   search within cited reference  option.
  • Related articles  helps you identify r esearch that's close ----algorithmically, at least -- to the item you started with. 
  • Authors whose names are hotlinked reveal publications pages -- where you migth find additional/related publications (and see their times cited, too!)
  • << Previous: HOLLIS: Searching Panoramically Across Harvard's Discovery Space
  • Next: Generating Research Leads From What You Have in Hand >>

Except where otherwise noted, this work is subject to a Creative Commons Attribution 4.0 International License , which allows anyone to share and adapt our material as long as proper attribution is given. For details and exceptions, see the Harvard Library Copyright Policy ©2021 Presidents and Fellows of Harvard College.

Reference management. Clean and simple.

The top list of academic search engines

academic search engines

1. Google Scholar

4. science.gov, 5. semantic scholar, 6. baidu scholar, get the most out of academic search engines, frequently asked questions about academic search engines, related articles.

Academic search engines have become the number one resource to turn to in order to find research papers and other scholarly sources. While classic academic databases like Web of Science and Scopus are locked behind paywalls, Google Scholar and others can be accessed free of charge. In order to help you get your research done fast, we have compiled the top list of free academic search engines.

Google Scholar is the clear number one when it comes to academic search engines. It's the power of Google searches applied to research papers and patents. It not only lets you find research papers for all academic disciplines for free but also often provides links to full-text PDF files.

  • Coverage: approx. 200 million articles
  • Abstracts: only a snippet of the abstract is available
  • Related articles: ✔
  • References: ✔
  • Cited by: ✔
  • Links to full text: ✔
  • Export formats: APA, MLA, Chicago, Harvard, Vancouver, RIS, BibTeX

Search interface of Google Scholar

BASE is hosted at Bielefeld University in Germany. That is also where its name stems from (Bielefeld Academic Search Engine).

  • Coverage: approx. 136 million articles (contains duplicates)
  • Abstracts: ✔
  • Related articles: ✘
  • References: ✘
  • Cited by: ✘
  • Export formats: RIS, BibTeX

Search interface of Bielefeld Academic Search Engine aka BASE

CORE is an academic search engine dedicated to open-access research papers. For each search result, a link to the full-text PDF or full-text web page is provided.

  • Coverage: approx. 136 million articles
  • Links to full text: ✔ (all articles in CORE are open access)
  • Export formats: BibTeX

Search interface of the CORE academic search engine

Science.gov is a fantastic resource as it bundles and offers free access to search results from more than 15 U.S. federal agencies. There is no need anymore to query all those resources separately!

  • Coverage: approx. 200 million articles and reports
  • Links to full text: ✔ (available for some databases)
  • Export formats: APA, MLA, RIS, BibTeX (available for some databases)

Search interface of Science.gov

Semantic Scholar is the new kid on the block. Its mission is to provide more relevant and impactful search results using AI-powered algorithms that find hidden connections and links between research topics.

  • Coverage: approx. 40 million articles
  • Export formats: APA, MLA, Chicago, BibTeX

Search interface of Semantic Scholar

Although Baidu Scholar's interface is in Chinese, its index contains research papers in English as well as Chinese.

  • Coverage: no detailed statistics available, approx. 100 million articles
  • Abstracts: only snippets of the abstract are available
  • Export formats: APA, MLA, RIS, BibTeX

Search interface of Baidu Scholar

RefSeek searches more than one billion documents from academic and organizational websites. Its clean interface makes it especially easy to use for students and new researchers.

  • Coverage: no detailed statistics available, approx. 1 billion documents
  • Abstracts: only snippets of the article are available
  • Export formats: not available

Search interface of RefSeek

Consider using a reference manager like Paperpile to save, organize, and cite your references. Paperpile integrates with Google Scholar and many popular databases, so you can save references and PDFs directly to your library using the Paperpile buttons:

academic research databases

Google Scholar is an academic search engine, and it is the clear number one when it comes to academic search engines. It's the power of Google searches applied to research papers and patents. It not only let's you find research papers for all academic disciplines for free, but also often provides links to full text PDF file.

Semantic Scholar is a free, AI-powered research tool for scientific literature developed at the Allen Institute for AI. Sematic Scholar was publicly released in 2015 and uses advances in natural language processing to provide summaries for scholarly papers.

BASE , as its name suggest is an academic search engine. It is hosted at Bielefeld University in Germany and that's where it name stems from (Bielefeld Academic Search Engine).

CORE is an academic search engine dedicated to open access research papers. For each search result a link to the full text PDF or full text web page is provided.

Science.gov is a fantastic resource as it bundles and offers free access to search results from more than 15 U.S. federal agencies. There is no need any more to query all those resources separately!

academic research databases

academic research databases

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BUS 255: Professional Planning and Practice for Internships & Careers

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Academic Research About your Industry

Recommended databases for most research topics.

  • Professional Associations+
  • New York Public LIbrary
  • Get Help from a Librarian

If you want to find out what college professors and other academics and scholars are publishing about your industry or career, consider searching library databases. Scholarship is published in books (often published by university presses) and academic journals. You can also search for print books in libraries and bookstores. Scholarly articles might help you develop your own ideas and ethics about your proposed career since such articles are not published by industry but by academia.

For example, Advertising Age trade magazine isn't going to be critical of the advertising world, but the British Journal of Social Psychology likely will.

academic research databases

Academic Search Ultimate ( A) A partly full-text article and indexing database that covers all academic disciplines. Academic or scholarly journal articles, trade publication articles, conference papers, and magazine and newspaper articles are here. Important: Click the “Search for Item” image if you don’t see a PDF or HTML link in an article. This is a powerful tool that searches all the other databases for the article. Try searching in the title or abstract for your terms. Put phrases between quotation marks.

academic research databases

Ebook Central (E) This is a 100% full text book database. You can read online, download chapters, print chapters, and download most books for a limited time. The best bet is to download PDF chapters, which you can have permanently. There are other tools in the database, as well.

note: Pace subscribes to MANY other databases, as well. View them by selecting the SUBJECT drowpdown menu.

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Citation Databases

  • Searching Scopus
  • Researcher Profiles
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  • Searching Web of Science
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  • Research Impact and Metrics

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Bibliometrics Overview

Welcome to Purdue University's Citation Databases Research Guide

Here you will find...

  • Information on citation databases
  • Descriptions of these databases
  • Helpful examples on how to use them
  • Use cases for each of the major citation databases
  • Useful tips and tricks on how to best make use of them

Here are some definitions of common terms made use of by citation databases

  • Bibliometrics is the statistical analysis of scholarly output like articles, book chapters, and reviews.
  • Altmetrics: is the statistical analysis of alternative forms of capture such as twitter impressions of a piece of scholarly output.

Some common metrics are the H-index, Journal Impact Factor, and the FWCI (called CNCI in Web of Science).

  • H-Index is a measure of how many times a journals published articles are cited, an index of fifteen means an article has been cited 15 times.
  • Journal Impact Factor (IF) – A measurement of how many times a journal’s published articles are cited by different researchers.
  • FWCI – Publication Field weighted citation indices indicate how the number of citations received by researcher’s publications compared to the average number for similar publications.
  • Category Normalized Citation Impact (CNCI) – Calculated using Web of Science, CNCI is “an indicator of impact normalized for subject focus, age and document type. A CNCI of 1 is at par with the world average, anything above 2 is twice the global average
  • SJR - Scimago Journal Rank is a measure of the "prestige" of journals which makes use of both the number of citations a journal accrues and the perception of those journals in the wider academic community
  • SNIP - Source Normalized Impact per Paper is a metric which accounts for the field specific differences between journals. The need for this is that some fields have different publishing practices, time frames, and constraints. This results in the need for a metric like SNIP which is calculated by comparing the citations per journal with the citation potential of the field as a whole, in other words it would measure of history journal against other history journals and vice versa for other academic disciplines

Here are the five most common Citation Databases' Key Strengths and Use Cases

Help Resources

  • Web of Science: Core Collection Access the world’s leading scholarly literature in the sciences, social sciences, arts, and humanities and examine proceedings of international conferences, symposia, seminars, colloquia, workshops, and conventions. -Science Citation Index Expanded (1900-present) -Social Sciences Citation Index (1900-present) -Arts & Humanities Citation Index (1975-present) -Conference Proceedings Citation Index- Science (1990-present) -Conference Proceedings Citation Index- Social Science & Humanities (1990-present) -Book Citation Index– Science (2005-present) -Book Citation Index– Social Sciences & Humanities (2005-present) -Current Chemical Reactions (1985-present) (Includes Institut National de la Propriete Industrielle structure data back to 1840) -Index Chemicus (1993-present) -Emerging Sources Citation Index (2005 – present)
  • Google Scholar Searches for scholarly materials such as peer-reviewed papers, theses, books, preprints, abstracts and technical reports from broad areas of research. It includes a variety of academic publishers, professional societies, preprint repositories and universities, as well as scholarly articles available across the web.
  • Dimensions Dimensions is a citations database which specializes in providing abstracts, citations, and patents to users. While the Library does not currently subscribe, you can access the free version of the database from this link

Freely accessible resource

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ENGL 137W: Writing for Academic Audiences: Articles/Databases

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  • Shortcuts when searching ACADEMIC SEARCH COMPLETE for ENGL 137
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How To Find Articles

This will check if we have access through a different database and our print collection. 

If we do not have access, you will be given an option to order it through  Interlibrary Loan (ILL).  Fill out the form and click "Submit." It takes about 2 business days to get articles.

What is Peer-Review?

Peer-review is an evaluation process in which qualified individuals within specialized field of study reviews literature before it becomes published.  This process helps keep standards held by the profession, improves the quality of work being published, and provides credibility & reliability to published work & authors publishing the work. The 3-minute video below describes and discusses the importance of peer-review and its process.

academic research databases

Databases for most topics in JOUIRNAL & MAGAZINES

  • Academic Search Complete A full-text interdisciplinary database that can filter to peer-reviewed and full-text literature. This is great resource for starting your research.
  • CQ Researcher Founded in 1923 as Editorial Research Reports, CQ Researcher is noted for its in-depth, unbiased coverage of health, social trends, criminal justice, international affairs, education, the environment, technology, and the economy. Reports are published weekly in print and online 44 times a year by CQ Press, a division of Congressional Quarterly Inc.
  • Opposing ViewPoints Resource Center A one-stop source for information on current social issues. Drawing on acclaimed series published by Greenhaven Press and other Gale imprints, OVRC features viewpoint articles, topic overviews, full-text magazine, academic journal, and newspaper articles, primary source documents, statistics, images and podcasts, and links to Websites.

Databases for most topics in SELECTED NEWSPAPERS

  • Oregonian (Newsbank) This link opens in a new window Full text access to the Oregonian, the newspaper of record for the state of Oregon. It is the largest newspaper in Oregon and the Pacific Northwest by circulation. 1861 - present
  • Statesman Journal This link opens in a new window Provides access to Salem's newspaper, covering local news and events, Oregon state government. 1999 - present
  • New York Times (1980 - present) This link opens in a new window Provides searchable full text. 1980 - present
  • Wall Street Journal This link opens in a new window Provides full text coverage of the worlds leading financial newspaper. Useful for current and historical information on international finance and economics, the stock market, and world events. 1984 - present
  • Access World News This link opens in a new window Full-text content of over 2,200 North American newspapers and more than 1,200 international newspapers, plus 300 wire services and over 200 broadcast news transcripts. Covers local, regional, and world issues, politics, government policies, sports, industries, cultural activities, schools, and the people and events in the community.

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Free Databases

EBSCO provides free research databases covering a variety of subjects for students, researchers and librarians.

Exploring Race in Society

This free research database offers essential content covering important issues related to race in society today. Essays, articles, reports and other reliable sources provide an in-depth look at the history of race and provide critical context for learning more about topics associated with race, ethnicity, diversity and inclusiveness.

EBSCO Open Dissertations

EBSCO Open Dissertations is a collaboration between EBSCO and BiblioLabs to increase traffic and discoverability of ETD research. You can join the movement and add your theses and dissertations to the database, making them freely available to researchers everywhere.

GreenFILE is a free research database covering all aspects of human impact to the environment. Its collection of scholarly, government and general-interest titles includes content on global warming, green building, pollution, sustainable agriculture, renewable energy, recycling, and more. 

Library, Information Science and Technology Abstracts

Library, Information Science & Technology Abstracts (LISTA) is a free research database for library and information science studies. LISTA provides indexing and abstracting for hundreds of key journals, books, research reports. It is EBSCO's intention to provide access to this resource on a continual basis.

Teacher Reference Center

A complimentary research database for teachers,  Teacher Reference Center  (TRC) provides indexing and abstracts for more than 230 peer-reviewed journals.

European Views of the Americas: 1493 to 1750

European Views of the Americas: 1493 to 1750 is a free archive of indexed publications related to the Americas and written in Europe before 1750. It includes thousands of valuable primary source records covering the history of European exploration as well as portrayals of Native American peoples.

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Top 10 Support Resources for K-12 Schools on EBSCO Connect

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Article Contents

Smartdb: an integrated database for exploring single-cell multi-omics data of reproductive medicine.

Equal contribution.

  • Article contents
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Zekai Liu, Zhen Yuan, Yunlei Guo, Ruilin Wang, Yusheng Guan, Zhanglian Wang, Yunan Chen, Tianlu Wang, Meining Jiang, Shuhui Bian, SMARTdb: An Integrated Database for Exploring Single-cell Multi-omics Data of Reproductive Medicine, Genomics, Proteomics & Bioinformatics , 2024;, qzae005, https://doi.org/10.1093/gpbjnl/qzae005

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Single-cell multi-omics sequencing has greatly accelerated reproductive research in recent years, and the data are continually growing. However, utilizing these data resources is challenging for wet-lab researchers. A comprehensive platform for exploring single-cell multi-omics data related to reproduction is urgently needed. Here we introduce the single-cell multi-omics atlas of reproduction (SMARTdb), which is an integrative and user-friendly platform for exploring molecular dynamics of reproductive development, aging, and disease, covering multi-omics, multi-species, and multi-stage data. We have curated and analyzed single-cell transcriptome and epigenome data of over 2.0 million cells from 6 species across whole lifespan. A series of powerful functionalities are provided, such as “Query gene expression”, “DIY expression plot”, “DNA methylation plot”, and “Epigenome browser”. With SMARTdb, we found that the male germ-cell-specific expression pattern of RPL39L and RPL10L is conserved between human and other model animals. Moreover, DNA hypomethylation and open chromatin may regulate the specific expression pattern of RPL39L collectively in both male and female germ cells. In summary, SMARTdb is a powerful platform for convenient data mining and gaining novel insights into reproductive development, aging, and disease. SMARTdb is publicly available at https://smart-db.cn .

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IMAGES

  1. The best academic research databases [Update 2024]

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  3. The best academic research databases [2022 update]

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    Single-cell multi-omics sequencing has greatly accelerated reproductive research in recent years, and the data are continually growing. However, utilizing these data resources is challenging for wet-lab researchers. A comprehensive platform for exploring single-cell multi-omics data related to reproduction is urgently needed.

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