phd position cancer research

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Cancer Biology PhD Program

Established in 1978, the interdisciplinary Cancer Biology PhD Program is designed to provide graduate and medical students with the education and training they need to make significant contributions to the field of cancer biology. The program is led by Laura Attardi, PhD, and Julien Sage, PhD, and currently has over 60 participating faculty members representing a variety of specialties.

Coursework during the first year equips students with a broad understanding of the molecular, genetic, cellular biological and pathobiological aspects of cancer. By the beginning of the second year, students have chosen a research advisor and begun work on their dissertation projects. An annual program conference provides students with an opportunity to present their research findings, receive feedback and forge collaborations with faculty and fellow students. 

The Cancer Biology program also sponsors a postdoctoral scholar track in which accepted MD and PhD scholars pursue research under the guidance of a faculty mentor. 

Program Directors

Laura Attardi

Catharine and howard avery professor of the school of medicine and professor of genetics.

Julien Sage

Elaine and john chambers professor of pediatric cancer and professor of genetics.

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PhD in Cancer Research

Search for solutions to one of medicine's greatest challenges with an innovative Cancer Research PhD from UNMC.

Why earn a PhD in Cancer Research?

Advancement in the detection and treatment of cancer continues to accelerate through ground-breaking research, yet cancer remains one of the most complex and challenging problems of biomedical research.

As a cancer researcher, you'll work to better understand the causes of cancer, and to find new ways to prevent, diagnose, and treat cancer.

We're in an exciting new dawn in biomedical science where we will see many cures previously deemed impossible.

Why earn a PhD in Cancer Research from UNMC?

Cancer research is a key area of research at UNMC, which features the National Cancer Institute-designated Fred & Pamela Buffett Cancer Center. The Cancer Research Doctoral Program, offered through the Eppley Institute for Research in Cancer and Allied Diseases , is the cornerstone of our National Cancer Institute-supported Cancer Biology Training Program.

The Cancer Research Doctoral Program is one of the seven programs within the Interdisciplinary Graduate Program in Biomedical Sciences and includes approximately 100 faculty from the Eppley Institute and other basic and clinical departments within UNMC. You'll work in state-of-the-art laboratories and participate in important cancer research with nationally and internationally renowned scientists.

Cancer researchers at UNMC are engaged in work that addresses the root causes of cancer, as well as the means of enhancing the detection and treatment. This research employs a wide range of animal and cellular model systems, includes both basic and translational research, and focuses heavily on the molecular basis of cancer. As a result, you'll receive broad-based training in all aspects of cancer biology and employ cutting-edge experimental approaches.

Our innovative program trains future scientists to approach cancer research knowledgeably and creatively and to enter careers in which they can make a significant contribution.

Program Snapshot

Education opportunities.

You'll receive advanced training in cancer research. We offer special courses on translational cancer research and grant writing and seminar presentation skills. You'll also have the chance to attend discussions of cancer cases by oncologists and participate in interdisciplinary clinical/basic cancer research groups.

Learn more about IGPBS

The Eppley Institute for Research in Cancer and Allied Diseases

The Eppley Institute is fighting cancer with some of the brightest minds in science. Faculty and students have access to state-of-the-art research equipment both within the Eppley Institute and in other shared on-campus facilities.

Careers & Outcomes

Program graduates are highly recruited for postdoctoral work in top laboratories at universities, government laboratories and private industry. Many graduates assume research or teaching careers in academia; others take research positions in biotechnology firms, government or pharmaceutical companies or in the health care or medical professions.

Recent Job Titles

• Senior Licensing Specialist
• Assistant Director of a Clinical Molecular Oncology Laboratory
• Director of Bioengineering
• Scientific Director
• Clinical Scientist
• Medical Resident

Recent Postdoctoral Fellowships

• Yale University
• Johns Hopkins University
• The Mayo Clinic
• Harvard University
• MD Anderson Cancer Center

Areas of Research

Causes of cancer.

This area of research includes evaluation of the genetic and environmental factors that contribute to cancer incidence, as well as cancer prevention. Research efforts include functional genomics, DNA damage and repair, nutrition and cancer, environmental risk factors, cancer genetics and animal models of cancer.

Molecular and Cellular Characteristics of Cancer

This research focuses on the differences in molecules and cells that help define cancer. The following avenues are taken in research at the molecular level: gene expression, signal transduction and structural biochemistry.

Diagnostics and Therapeutics

State-of-the-art technology couples with cutting-edge cancer research to identify new ways of diagnosing and treating cancer. Several research innovations are used, including high-throughput screening for novel anti-tumor drugs, analysis of unique clinical cancer resources, identification of new cancer biomarkers and immunotherapy.

Connect with Us

For more information, please contact Dr. Joyce Solheim ( [email protected] ) or Misty Pocwierz-Gaines ( [email protected] ) in the UNMC Eppley Institute for Research in Cancer & Allied Diseases.

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Training the next generation of cancer researchers

Program Overview

The Cancer Biology program spans many disciplines, including cell biology, genetics, biochemistry, microbiology, pharmacology, pathology, epidemiology, bioinformatics, and immunology, to name a few. It represents a unique set of training and educational activities that, taken collectively, expose the student to the full breadth of cancer biology while allowing immersion in a specific dissertation topic of the student’s choice.

Faculty in the Program are interested in a number of topic areas, including: Cancer genetics; Cancer epigenetics; Tumor immunology; Cell biology; Epidemiology; Pathology; Tumor metabolism; Bioinformatics; Cancer drug discovery.

Projects range from fundamental studies of basic biological processes to translational research aiming to move basic findings into the clinic.

Apply through our PIBS application

Students in the Cancer Biology program are required to take core courses in Cancer Biology and Bioinformatics. PIBS core courses should be taken to fill gaps in knowledge or together with other electives, to strengthen a student’s knowledge base in an area of interest. Students are also required to participate in the Cancer Biology Seminar Series for the duration of their time in the program. The Cancer Biology Seminar Series course provides not only continued exposure to the breadth of cancer research but also experience in honing seminar presentation skills.

Preliminary Examination

The preliminary exam consists of two checkpoints. The first is a didactic exam that evaluates students’ understanding of the fundamentals of cancer biology. This exam will take place in May at the end of the first year in order to advance to PhD candidacy. The second checkpoint takes place in the winter semester of the second year and is comprised of two steps, the writing of a written research proposal (NIH format) and the oral presentation of the proposal to the preliminary exam committee.

Teaching Requirement

There are no formal requirements for teaching in the Cancer Biology program. However, opportunities exist for senior students to serve as teaching assistants for one term of the introductory cancer biology class. In addition, students with an interest in teaching are encouraged to pursue the U-M Graduate Teaching Certificate as a way to prepare themselves for careers that will involve college-level teaching.

Students help organize the annual Cancer Biology retreat, including selecting the keynote speaker. This fun and informal setting gives students, postdocs, and faculty the opportunity to present their research, generate collaborations, and receive feedback. Trainees and faculty give oral presentations and all members of our cancer research community are invited to deliver poster presentations. The retreat is a great opportunity for first year PIBS and MSTP students to explore the research and meet students and faculty in the Cancer Biology program.

Research Seminar/Journal Club

The Cancer Biology Graduate Program sponsors a weekly seminar program that runs through the academic year. Students are encouraged to nominate and host external cancer researchers whose work they find exciting and cutting edge. Senior students participate by giving oral presentations on their research progress and second year students give journal clubs highlighting the research of invited speakers.

Social Events

During the summer, students get together for a picnic and canoe trip that includes the summer undergraduate research students. At the beginning of the academic year, the program director hosts an orientation dinner for all to welcome the new students. There is an annual year-end holiday party along with monthly happy hours for students to relax in an informal setting.

Extracurricular

Students are involved in a variety of activities outside of lab. Many students give back to the community through educational and community outreach programs. Cancer Biology students have fun by attending sporting events, participating in outdoor activities, club sports, and arts/crafts events, and enjoying food/drink and museums – all which Ann Arbor offers.

The impact of cancer on all our lives emphasizes the need to continue training individuals to pursue research into its cure and prevention. The ongoing investment of the National Cancer Institute and non-governmental funding organizations including the American Cancer Society, The Leukemia and Lymphoma Society, and others, means that research at universities and research institutes will remain a high priority, thereby providing jobs for cancer researchers with doctoral degrees. The complexity of cancer leads to the unfortunate realization that it will take many years to unlock all of its mysteries, resulting in a long-term need for persons trained in the field.

Besides the tremendous investment in basic cancer research at universities and non-profit organizations, the development of new therapeutic modalities for cancer represents a large percentage of pharmaceutical company expenditures. According to IMS Health, the global oncology market was growing at 6.8% overall in 2011, double that number in the pharmaceutical sector. In 2013, the worth of the market was approximately $75 billion just in the US. Given this huge investment in cancer research, the job market for individuals with doctoral degrees in cancer biology is very large and growing.

Learn more about the Department of Cancer Biology.

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Cancer Institute MPhil/PhD

London, Bloomsbury

A full or part-time research degree at the UCL Cancer Institute offers an unrivalled foundation for building a career in cancer. World-class facilities, expert supervision and wide-ranging training opportunities will give you the skills and network to help shape cancer research and practice in academia, biomedicine, or healthcare.

UK tuition fees (2024/25)

Overseas tuition fees (2024/25), programme starts, applications accepted.

• Entry requirements

A minimum of an upper second-class UK Bachelor’s degree in a relevant discipline or an overseas qualification of an equivalent standard.

The English language level for this programme is: Level 3

UCL Pre-Master's and Pre-sessional English courses are for international students who are aiming to study for a postgraduate degree at UCL. The courses will develop your academic English and academic skills required to succeed at postgraduate level.

Further information can be found on our English language requirements page.

Equivalent qualifications

Country-specific information, including details of when UCL representatives are visiting your part of the world, can be obtained from the International Students website .

International applicants can find out the equivalent qualification for their country by selecting from the list below. Please note that the equivalency will correspond to the broad UK degree classification stated on this page (e.g. upper second-class). Where a specific overall percentage is required in the UK qualification, the international equivalency will be higher than that stated below. Please contact Graduate Admissions should you require further advice.

About this degree

Research within the UCL Cancer Institute is diverse and spans various disciplines including molecular and cellular biology, cancer genetics, immunology, genetic engineering, cancer therapeutics and bioinformatics.

Research students on this programme join one of five research departments within UCL ' s Cancer Institute:

• Cancer Biology
• Haematology
• Clinical Trials.

You will develop your research hypothesis with your supervisors and undertake novel laboratory, bioinformatic or clinical research as part of their research team. You will regularly discuss your data and analyses with your supervisors and share your findings in a variety of forums, ideally leading to presentations at conferences and publication of your work.

Knowledge and skills development is a core priority of the programme, and you will be supported in this area by a supervisory team. In addition to your principal supervisor, you will have a thesis committee which comprises a secondary (subsidiary) supervisor and between one and three thesis committee members.

In your first year, you will have a compulsory training programme run by the Cancer Institute that will improve your research skills and provide networking opportunities. This is in addition to the optional research methods modules offered on the UCL Doctoral Skills Training Programme.

Who this course is for

This course will appeal to high achieving students who want to join a world-class centre in cancer research. It is suitable if you have a strong academic background as a clinician, scientist, or other profession focused on cancer. We welcome students come from around the world and your study will be based in London.

What this course will give you

This programme offers you the following benefits and opportunities.

• A collaborative research environment that spans basic research, translational medicine, and clinical applications.
• Close links with associated clinical trials facilities, experimental cancer medicine centres, biobanking facilities and associated partners and hospitals in London such as the Royal Free Hospital, UCL Hospitals (UCLH), Cancer Research UK and the Crick Institute.
• Developing skills including bench and technical skills, critical evaluation of scientific literature, experimental planning and design, interpretation of data results, presentation/public speaking skills, time and project management, working within a team, working independently, and writing for various audiences.

Making an impact

Case study: Catching and treating more prostate cancers worldwide

Thanks to UCL research, millions of men each year benefit from more accurate diagnosis and treatment of prostate cancer with significantly fewer side effects.

The foundation of your career

Our excellent facilities, supervision and training opportunities prepare you for future careers in academic posts, industry, business, biomedicine, and healthcare.

The lecture on CAR-T for the Cancer MSc programme was the first time I can remember thinking 'Wow! I am interested in this.' Now, my PhD involves the targeting of a glioblastoma-specific antigen and exploring different constructs. Morgan Palton Cancer Institute, PhD Learn more about Morgan

Employability

Graduates go on to academic posts at universities around the world. Other career pathways include laboratory management, research, industry, clinical trials co-ordination, scientific writing and editing, and sales and consulting.

You will also be well placed to go onto further medical training or to take up a clinical post.

The programme is designed to give you networking opportunities throughout your period of study.

These include weekly internal divisional seminars, a fortnightly external speaker seminars and reception, and student poster sessions. You will also attend the annual Cancer Institute Conference, as well as national and international research conferences, and academic careers days.

After graduating, you will be able to join the Institute's alumni network on LinkedIn.

Teaching and learning

Most of your research will be carried out independently. There will also be a series of training requirements that you will need to complete in the early stages of the programme.

All research students attend a training programme on lab skills from January to July in the first year, which covers:

• Human Tissue Act and the Biobank
• Tissue Preparation and Staining
• Basics of Proteomics
• Principles of Good Clinical Lab Practice
• Clinical Trial Design and Regulation
• In vivo Study Design and Regulation
• Preclinical Radiotherapy
• Single Cell Analysis.

Your first milestone will be to upgrade from MPhil to the PhD degree. For this, you will submit and present a report. In your final year, you submit a thesis covering your research and discuss this at a formal interview known as a viva examination.

Most of your time will be spent conducting independent research, alongside regular meetings with your supervisory team and completing your training requirements. We also encourage you to attend relevant research events at UCL and elsewhere.

Research areas and structure

• Antibody-based therapeutics for imaging and treatment of cancer
• Brain cancer and stem cells
• Cellular and gene therapy for cancer and other blood-related disorders
• Chromosomal DNA replication and cancer
• Effects of tumour biology on therapeutic response, tumour immunology
• Epigenetic changes and cancer
• Genetics of sarcoma, acute leukaemia, chronic leukaemia and myoproliferative diseases
• Medical genomics, cancer systems, science and biomedical informatics
• Signalling networks
• Stratified/personalised cancer medicine
• Therapeutic drug-DNA interactions
• Translational projects, clinical trials and epidemiology
• Viral oncology.

Research environment

UCL is a top-rated university in the UK for research strength in the Research Excellence Framework (REF 2021). Our scientists have an international reputation for leading basic, translational, and clinical cancer research and the Cancer Institute is uniquely positioned to leverage the multidisciplinary nature of UCL by engaging a range of disciplines to transform cancer research.

You will join a community of over 300 research scientists and 120 research students within the Cancer Institute. Our combination of fundamental cancer research, clinical links with UCLH and the Royal Free Hospitals, and collaborative links with the Crick Institute and Cancer Research UK, make the Cancer Institute an exciting environment for basic and translational research into cancer.

In addition to individual supervision from your thesis committee and the UCL Doctoral Skills Development Programme, the Cancer Institute runs a series of skills workshops between January and October of your first year. Some of these are project specific, such as knowledge and intellectual abilities, statistics analysis, and writing research papers or grants.

Other training focuses on transferable skills, including personal effectiveness, engagement influence and impact, research governance and organisation, and networking. You can also gain training credits by doing certain activities which are listed on the Cancer Institute Training page .

You will be invited to discuss your data and conclusions at research team meetings, Institute Research in Progress talks, the annual Cancer Institute conference and Research Student poster day. You will also be encouraged to present at relevant international conferences and, where appropriate, to contribute towards scientific publications in your field.

The length of registration for research degrees is usually three to four years for full-time study.

When you accept your place on the programme, you will initially register for an MPhil. You will be eligible to upgrade to PhD student status between 9-18 months.

Within three months of joining the programme, you will be expected to agree the basic structure of your research project with your supervisor, along with the appropriate research methods and a realistic plan of your work.

You will then need to produce and submit a detailed outline of your proposed research for comments and feedback. Following that, you will be ready to undertake the project as part of your supervisor’s research team, sharing your ideas and drawing on the knowledge, expertise, and support of the team.

In your second year, you will continue to explore your research hypothesis and collect and analyse novel data. You will also be expected to upgrade from an MPhil to a PhD.

To successfully upgrade to a PhD, you will need to submit a report summarising your research to date, and to present and answer questions about this work at a viva examination. You will also be expected to present your research to the department at a Research in Progress seminar.

In your third year, you will be expected to complete your data collection and analysis, and to prepare your thesis. You will also be encouraged to present your findings at an international conference or the annual Cancer Institute conference.

Following your third year, you may be eligible to transfer to what is termed 'completing research status' for one year to complete your thesis writing and final viva examination.

The length of registration for the research degrees is usually five years for part-time study.

When you accept your place on the programme, you will initially register for an MPhil. You will be eligible to upgrade to PhD student status between 15-30 months.

Within five months of joining the programme, you will be expected to agree the basic structure of your research project with your supervisor, along with the appropriate research methods and a realistic plan of your work.

In your second and third years (18-36 months), you will continue to explore your research hypothesis and collect and analyse novel data. You will also be expected to upgrade from an MPhil to a PhD.

In your fourth and fifth years, you will be expected to complete your data collection and analysis, and to prepare your thesis. You will also be encouraged to present your findings at an international conference or the annual Cancer Institute conference.

Following the fifth year, you may be eligible to transfer to what is termed 'completing research status' for two years to complete your thesis writing and final viva examination.

Accessibility

Details of the accessibility of UCL buildings can be obtained from AccessAble accessable.co.uk . Further information can also be obtained from the UCL Student Support and Wellbeing team .

Where you'll study

At the UCL Cancer Institute, you will join a scientific community of over 400 talented scientists. We are dedicated to discovering new techniques in cancer detection and treatment that can make a different to the lives of cancer patients. Our undergraduate, taught masters and PhD programmes reflect the depth and breadth of research expertise within the UCL Cancer Institute. Teaching is predominantly based at the Hampstead and Bloomsbury campuses.

Fees and funding

Fees for this course.

The tuition fees shown are for the year indicated above. Fees for subsequent years may increase or otherwise vary. Where the programme is offered on a flexible/modular basis, fees are charged pro-rata to the appropriate full-time Master's fee taken in an academic session. Further information on fee status, fee increases and the fee schedule can be viewed on the UCL Students website: ucl.ac.uk/students/fees .

Additional costs

Students receive a free printing allowance each year and pay for any additional printing ( see details ). You may also face additional expenses if you attend conferences. The cost depends on the location, exchange rates, and the price of travel and accommodation, but this may be between £200 and £500 per event, based on typical events / destinations attended by recent students. The Cancer Institute provides two competitive travel scholarships each year to support research students attending training workshops or international conferences.

If you are doing a wet lab project, there may be an Additional Fee Element (AFE, also known as bench fees). This is an additional annual cost related to consumables, equipment or materials based on your individual project. This is payable by your sponsor, or yourself, if self-funding. These additional costs depend on the project and will be the same for home and overseas students.

For more information on additional costs for prospective students please go to our estimated cost of essential expenditure at Accommodation and living costs .

Funding your studies

Annual CR-UK funded clinical fellowships and non-clinical PhD studentships are available. Please check the Cancer Institute website for details. Other funded studentships will also be advertised on the Institute's website as they become available. Some of our students seek funding from their home country or cancer charities.

For a comprehensive list of the funding opportunities available at UCL, including funding relevant to your nationality, please visit the Scholarships and Funding website .

Your first steps are to find a supervisor and funding before applying. You should check both the UCL and the Cancer Institute's studentships to apply for specific projects with grants. You can also reach out directly to any potential supervisor, particularly if you have funding in place from another source. You can identify Principal Investigators via the Cancer Institute website and research them individually. If you need help, please see applying for graduate research study or contact the Admissions Tutor on [email protected].

You can apply at any time. However, there are three entry points over the year. Deadlines and start dates are usually dictated by funding arrangements and supervisor availability, so discuss this with your supervisors.

Please note that you may submit applications for a maximum of two graduate programmes (or one application for the Law LLM) in any application cycle.

Choose your programme

Please read the Application Guidance before proceeding with your application.

Year of entry: 2024-2025

Got questions get in touch.

Cancer Institute

[email protected]

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15 PhD positions in cancer research

The Innovative Training Network (ITN) “PIPgen – PI3K/PTEN-related monogenic disease to understand cancer" is recruiting 15 highly motivated PhD candidates.

Application deadline: 27 June 2021

Host institutions:

Josep Carreras Leukaemia Research Institute, Badalona, Spain

University College of London, London, UK

Université de Paris, Paris, France

Erasmus MC, Rotterdam, Netherlands

Institut national de la santé et de la recherche / Université de Toulouse III, Toulouse, France

Amsterdam University Medical Centres ( UMC), Amsterdam, Netherlands

Cambridge University, Cambridge, UK

Radboud universiy medical centre, Nijmegen, Netherlands

CIC bioGUNE , Bilbao, Spain

Kither Biotech, Torino, Italy

qGenomics, Esplugues del Llobregat, Spain

About the PIPgen network

The PIPgen network brings together 9 leading European basic and clinical institutions and 3 private companies experts in the PI3K/PTEN- related diseases, to train 15 researchers in a wide range of scientific and complementary competences. Selected candidates will carry out specific projects under the supervision of a Principal Investigator within one of the 11 world-leading European host institutions from the network. They will also perform secondments in other institutions within the network to provide the needed interactions to achieve research and training excellence, and to improve their future career perspectives.

Fellows will be enrolled in a PhD programme and will receive an outstanding and tailored training designed specifically for them. The embedding within the PIPgen network, with experienced trainers from academia and industry and from two research environments (clinical and basic), offers a unique multidisciplinary and multisectoral training opportunity in the field of PI3K/PTEN-related diseases.

Scientific project

PIPgen stems from the emerging links between monogenic rare diseases and cancer, and how these fields can cross-fertilise and inform an integrated approach to both their understanding and treatment. Monogenic diseases offer ‘clean’ molecular, cellular and organismal information about the affected genes, whereas cancer is a compendium of genetic and epigenetic perturbations illustrative of complex diseases. Genetic alterations in the phosphoinositide 3-kinase ( PI3K)/PTEN pathway are a common event in both monogenic rare diseases and in cancer, presenting a truly unique paradigm of which PIPgen will take advantage. PIPgen aims to critically contribute by providing a dynamic learning strategy to enhance our understanding of the PI3K/PTEN pathway based on the molecular, biological and clinical integration of both pathological scenarios. PIPgen has been conceived with the view to make a real clinical and therapeutic impact without losing focus on the underpinning basic bioscience .

PhD Positions

PhD Project 1: Mechanism of action of PIK3CA mutation in cancer and overgrowth

Activating PIK3CA mutations lead to cancer and the PIK3CA -related overgrowth spectrum (PROS). Despite years of investigation, many questions remain about PIK3CA biology, signalling and pathway regulation. The aim of this project is to understand context-dependent and PIK3CA -mutant-specific biology, and how to therapeutically interfere with this pathway, both in cancer and PROS. We have made several interesting novel observations on PIK3CA biology and signalling that will be explored in this project, using advanced genetic and pharmacological PI3K approaches. Drug interventions will be tested in in vitro and in vivo studies.

Host: University College of London (UCL), UK

Supervisor : Prof Bart Vanhaesebroeck

Doctoral programme: University College of London

Envisioned secondments : Josep Carreras Institute , qGenomics

To apply for the UCL positions, in addition to the procedures outlined here, a further application will need to be completed via the UCL website – this is to conform with UCL’s own recruitment process. This second step is not yet available online, but we will inform candidates as soon as it opens.

PhD Project 2: Understanding the physiopathology of PROS

A challenging issue is the broad clinical presentation of PROS patients. To favour the inclusion of patients in potential clinical trials, stratification is mandatory. Based on our clinical expertise, we intend to classify patients according to the tissue layers that are involved in the malformation. To better understand the different subgroup of patient phenotypes, we have generated mouse models expressing oncogenic PIK3CA in specific tissues (including adipose, osteoblast, lymphatic, endothelial cells, muscle, Schwann cells). With a specific focus on veins and lymphatic vessels, ESR2 will express PIK3CAmut in genetically modified mouse models, followed by characterising their macroscopy phenotype, scRNAseq, and culture of lesion-derived cells.

Host: Université de Paris , France.

Supervisor : Prof Guillaume Canaud

Doctoral programme: Université de Paris

Envisioned secondments : KITHER, UCL

The selected candidate will have to undergo a second row of application in order to formally be admitted and allowed to enrol in the Université de Paris.

PhD Project 3: Improving recognition of patients with PHTS phenotypes by easy-to-apply sets of clinical criteria

PTEN Hamartoma Tumour Syndrome (PHTS) is a rare genetic predisposition that results in a broad spectrum of diseases. Most of these disesase are on their own common in the general population which hampers recognition of these rare PHTS patients. In addtion, each disease expression of PHTS is diagnosed by different health care disciplines and at different ages, such as skin lesions (dermatologist), vascular malformation (radiologist), developmental delay (neurology), an enlarged thyroid (endocrinologist) or breast cancer (oncologist/surgeon). We will determine easy-to-apply sets of clinical criteria that can be assessed by each healthcare provider who diagnoses a common feature of PHTS. In a large cohort of PHTS patients and PTEN-negative control patients extended clinical characteristics will be collected and assessed. The best performing clinical criteria will be assessed for futher implementation.

Host: Radboud university medical centre , NL.

Supervisor : Prof. Dr. Nicoline Hoogerbrugge and Dr. Janet Vos

Doctoral programme : Radboud University Nijmegen The Netherlands

Envisioned secondments : Gqenomics, cic-BIOgune

Position requirements: epidemiological and (bio)medical background, and understanding written Dutch is required.

PhD Project 4: Understanding vascular malformations in PHTS

30% of the patients with PHTS suffer from vascular malformations. Yet, this clinical condition has been under investigated in PHTS patients. ESR4 will: establish endothelial and epithelial cell models of the disease by introducing PTEN mutations and characterise their functional effects, cellular phenotyes and genetic instability. Primary endothelial cells derived from PHTS patients will be isolated, an in vivo model of the disease using a transgenic mouse model will be generated, combining a germline heterozygous background with a second PTEN hit under the control of a vascular-specific promoter, and the models will be screened for corrective treatments in FDA-approved drug screen . Biology and preclinical insight of these PHTS-derived vascular malformations models will be cross-compared with PHTS-derived epithelial tumours.

Host: Institut de Recerca contra la Leucèmia Josep Carreras (Josep Carreras Institute), Spain.

Supervisor : Dr. Sandra Castillo

Doctoral programme : University of Barcelona

Envisioned secondments : Radboudumc, U-Paris.

PhD Project 5: Biomarkers of chronically hyperactivated PI3Kδ in patients with APDS

Activated PI3 kinase Delta Syndrome (APDS) is a rare disease previously discovered by the group of Prof Sergey Nejentsev ( Angulo et al, Science, 2013 ). It is caused by mutations that increase PI3 kinase δ activity. APDS patients are immunodeficient and have high risks of bronchiectasis, autoimmune manifestations and lymphomas, suggesting that hyperactivated PI3 kinase δ contributes to the pathogenesis of these disorders. ESR5 will use advanced cell and molecular techniques to characterise immunological consequences of chronically hyperactivated PI3 kinase δ in APDS as well as related common disorders.

Host: Amstersdam UMC (location VUmc), NL.

Supervisor : Prof Sergey Nejentsev

Doctoral programme : Vrije University of Amsterdam (4 Years PhD Program)

Envisioned secondments : University of Cambridge, Inserm

PhD Project 6: Studying T cell exhaustion in a model of APDS

Patients with APDS experience T cell exhaustion in response to chronic activation by herpes family viruses. Similarly, mice with an activated PI3Kd mutation raise highly effective immune responses to acute viral infections, but preliminary data show they fail to control chronic infections effectively. We will generate proteomic data sets of T cells obtained from infected mice and map PI3Kd-dependent changes. Candidate genes responsible for T cell exhaustion in a PI3Kd-dependent manner will be CRISPR out to determine the mechanisms of T cell exhaustion. Pharmacological strategies to reverse T cell exhaustion will be explored.

Host: University of Cambridge (UCAM), UK

Supervisor : Klaus Okkenhaug

Doctoral programme : University of Cambridge

Envisioned secondments : Amstersdam UMC, KITHER

PhD Project 7: Role of PTEN/PI3K mutations in increased risk for autism spectrum disorder (ASD).

Mutations in the PTEN and PI3K genes have been described to increase the risks for ASD. However, the function of these proteins in the brain and their role in ASD are largely unknown. ESR7 will: characterize the interactions between PTEN and PI3K mutations and the mTOR pathway in neurons at the molecular and cell morphological level; perform behavioural phenotyping of transgenic mouse models of PTEN and PI3K mutations found in the patient cohorts behavioural and cognitive tests in patient cohorts; use functional ultrasound to investigate brain-wide activity in one of the mouse models

Host: Erasmus University Medical Center Rottedam (ErasmusMC), NL.

Supervisor : Dr. Aleksandra Badura

Doctoral programme : Erasmus University (4 years PhD Programme)

Envisioned secondments : UCAM, UCL

PhD Project 8: The role of PI3Kdelta in solid tumours and its modulation using novel pharmacological tools

There is emerging evidence for a cancer-cell-intrinsic role of PI3Kdelta in solid tumours, but this has not been formally proven. ESR8 will investigate the role and mechanism of action of cancer-cell-intrinsic PI3Kdelta in solid tumours, and its importance in responsiveness to novel pharmacological tools that modulate PI3Kdelta activity (such as IOA-244 from iOnctura and others). The focus will be on cell types expressing high levels of PI3Kdelta, including glioblastoma and melanoma, with some studies on specific lymphoma subtypes. ESR8 will perform CRISPR-out the PI3Kdelta gene from selected tumour cell lines to investigate the impact in cancer-relevant biology in vitro and in vivo , using advanced signalling studies by proteomic and genomic analyses (such as RNAseq, epigenetics) and cell biology.

Host: University College of London , UK.

Envisioned secondments : iOnctura, UCAM

PhD Project 9: Mechanical stress & signal integration by PI3Ks for the control of tumour growth.

Approaching mechanical properties of tumours appear as a novel means to treat cancer. PI3K signalling is increased in more than 50% of cancer patients, how PI3K integrates mechanical signal and whether its inhibition could have an impact on the efficiency of these novel strategies is unknown. ESR9 will: establish an in vitro patient or murine organoid model that mimic mechanical stress (compression, tension, shear) and genetic heterogeneity found in pancreatic cancer, map how PI3K activity influences response to mechanical stress in various genetic environments and determine the mechanosensitive determinants that prevent cell growth & migration, validate the most efficient approach in preclinical settings.

Host: Institut national de la santé et de la recherche / Université de Toulouse III (INSERM), France

Supervisors : Dr. Julie Guillermet-Guibert

Doctoral programme : Université Toulouse III – Paul Sabatier

Envisioned secondments : Josep Carreras Institute, U-Paris

PhD Project 10: (poly)Genic alterations which emerge from monogenic PTEN-loss driven prostate cancer

Prostate tumours are associated to the process of aging and lifestyle, which could relate to the progressive accumulation of mutations or to the decline of systemic antitumoral capacity. ESR10 will characterise in a PTEN loss-driven mouse model, the impact of aging and lifestyle factors in the susceptibility to develop prostate lesions and we will combine this information with data derived from human prostate cancer specimens. We will perform molecular characterisation of the tumour and stromal component, seeking to define key drivers of the tumorigenic process that can be mechanistically deconstructed. We will capitalize on human prostate cancer multi-omics datasets to determine the clinical relevance of the drivers derived from the mouse model. It is intended that ESR10 will have a predominant training in computational biology, complemented with cellular and molecular biology (gene editing technologies that enable us to alter the prostate genetic makeup based on the findings derived from monogenic disease that will be produced in PIPgen). This project has the impact to provide new research tools to the field while generating key knowledge that can be critical for prostate cancer management.

Host: CIC bioGUNE (cic-BIO), Spain

Supervisors : Dr. Arkaitz Carracedo and Isabel Mendizabal

Doctoral programme : Universidad País Vasco

Envisioned secondments : qGenomics, Inserm

PhD Project 11: Understanding the role of activated PI3Kδ mutations in B cell lymphoma

Patients with APDS are at increased risk of developing B cell lymphoma. ESR11 will characterise a novel mouse model of B cell lymphoma driven by activated PI3Kδ and BCL6. The student will determine the sensitivity of these B cells to clinically approved inhibitors, such as Idealisib, Ibrutinib and Venetoclax. ESR11 will also develop protocols to initiate a CRISPR/Cas9-based screen to fine additional vulnerabilities in these B cell lines. Moreover, the student will determine how different T cell subsets can either promote or suppress lymphoma development with relevance to cancer immunotherapy.

Envisioned secondments : CIC bioGUNE, Josep Carreras Institute

PhD Project 12: Treg evolution in B cell lymphoma patients under Idelalisib

The PI3Kδ inhibitor, Idelalisib (IDL), is approved for chronic lymphocytic leukemia (CLL) and follicular lymphoma (FL), but induces many toxicities. In other B-cell indolent lymphomas, clinical responses are also reported, but with fewer tolerance concerns. The reason for this high activity and fewer safety issues observed in a cohort of CLL/FL patients (treated at IUCTO) is not understood. To identify cellular mechanisms at the origin of these differential responses, ESR12 will: analyse single-cell experiments in spleen from FL or splenic marginal zone lymphoma (SMZL) patients, monitor the evolution of patient circulating immune cell population (incl. Treg) under treatment to explain activity/toxicities, investigate activity/toxicity events linked to other PI3Kδ drug and dissect molecular mechanisms linked to heterogeneity of response ex vivo.

Supervisors : Dr. Julie Guillermet-Guibert and Dr. Loïc Ysebaert

Envisioned secondments : iOnctura, ErasmusMC

PhD Project 13: To identify PI3K vascular-related therapies which enhance immunoregulation flux

Vascular growth abnormalities are a hallmark of Pik3ca-related vascular tumours. Drugs targeting PI3Ka in tumours have proven to inhibit vessel growth, enhance hypoxia and impair antitumor immunity. ESR13 will take advantage of a collection of mouse models that allow to express diferent variants of Pik3ca oncogenic mutations (from low to high PI3K signalling) in endothelial cells, to study cell growth and immune infiltration. Vascular growth in the aforementioned mice will be followed by histological, FACS and molecular characterization by RNAseq of endothelial cells and immune populations. Upon identifying, possible targeting approaches, ESR13 will apply combinatory therapies to target vascular and immune cells.

Host: Institut de Recerca contra la Leucèmia Josep Carreras (JOSEP CARRERAS INSTITUTE), Spain.

Supervisor : Dr. Mariona Graupera

Envisioned secondments : Inserm, UCL

PhD Project 14: To screen and analyse the drug-like profile of compounds targeting PI3K

KITHER has developed two proprietary chemical moieties that modulate PI3K signal transduction events; (1) KIT2012 which has been optimised for inhaled treatment, and (2) KIT2014 has the ability to block PI3Kg scaffolding functions. ESR14 will apply them in Cystic Fibrosis (CF) disease and the severe and lethal Idiopathic Pulmonary Fibrosis (IPF). ESR14 will establish an in vitro cellular model of CF to characterise the role of PI3Kg and of its modulation in the pathogenesis of CF. Immortalised epithelial cells carrying the most prevalent mutation found in CF patients will be used to identify the underlying mechanisms. In parallel, transgenic animals and models of obstructive (CF-like) and restrictive (IPF) airway disease will be generated to characterise the contribution of PI3K in the diverse cell subpopulations (immune cells, epithelial, fibroblasts) that participate in pathogenesis. Secretory mechanisms, ion fluxes, proliferation and membrane dynamics will be assessed

Host: Kither Biotech (KITHER), Italy

Supervisor : Prof. Emilio Hirsch

Doctoral programme : University of Torino (4 years PhD Programme)

Envisioned secondments : University of Cambridge, Josep Carreras Institute

PhD Project 15: Improving accuracy and time-to-diagnosis of rare disease by developing AI-based algorithms

Next generation sequencing technologies have accomplished the long-awaited milestone of sequencing a genome at a cost below $1000. This makes it possible that millions of people affected by rare diseases can benefit from a diagnostic genetic test. However, once genome or exome sequence is produced, variant annotation, prioritisation and ultimately interpretation in the clinical and familial context, still remains the most important and costly bottleneck. ESR15 will develop a software that incorporates Artificial Intelligence algorithms at different steps and facilitates data interpretation, so at the end, the procedure is faster, more robust, and reliable. ESR15 will develop different machine learning algorithms to improve the process key steps: 1) automation of clinical history gathering into HPO terms, 2) variant categorisation according to ACMG classification, 3) prioritisation of disease-causing mutations, in the scope of the informed phenotype and variants identified.

Host: qGenomics (qG), Spain

Supervisor : Dr. Lluis Armengol

Envisioned secondments : U-Paris, Amstersdam UMC

REQUIREMENTS:

Eligibility criteria:

We welcome applications from PhD candidates from any country fulfilling the following criteria:

Eligible candidates must not have resided or carried out their main activity (work, studies, etc.) in the country of their host institution for more than 12 months in the 3 years immediately prior to their recruitment by the host institution (i.e. the starting date indicated in the employment contract/equivalent direct contract).

Eligible candidates shall at the date of recruitment by the host institution (i.e. the starting date indicated in the employment contract/equivalent direct contract), be in the first 4 years (full-time equivalent research experience) of their research careers and not have been awarded a doctoral degree.

Eligible candidates must have a master’s degree relevant for the chosen position (including biology, medicine, biochemistry, bioinformatics or a related discipline, depending on each PhD project) or its equivalent that would entitle them to a doctorate or must hold an official university qualification from a country of the European Higher Education Area with a minimum of 300 ECTs of official university studies.

Candidates must have a high level of proficiency in written and spoken English, which will be assessed with the motivation letter and the interview, respectively.

For applicants of project 3 at Stichting Radboud universitair medisch centrum , in Netherlands, Dutch will be required and epidemiological background will be considered

ADDITIONAL INFORMATION:

Application and selection process

The application will be done through an online application platform to be found on the PIPgen website: www.PIPgen.eu . Applications must be in English. Each applicant may apply to a maximum of three individual research projects .

Eligible applications will be ranked on the basis of CVs and merits by a selection committee. The 3 best candidates for each position will be invited for a virtual interview by 21-23 July 2021 where the final candidates will be selected.

Applicants with a positive evaluation but not selected will be included on a reserve list to cover eventual future positions and might be contacted at a later stage.

Announcement of preselection results and call for interviews: 15th July 2021

Recruitment virtual Workshop: Short-listed candidates will be interviewed between 21-23 of July 2021.

Announcement of pre-selected candidates: 9 th of August 2021

Communication of the final results: 13 th of August 2021

Tentative start of the fellowship: Between September 2021 and February 2022

3-year full-time employment contract (salary depends on the country of the recruitment considering both local and MSCA regulations for Early Stage Researchers and their family status at the time of the recruitment).

Enrolment in a PhD programme (In case of 4 years University Programmes, a 4th year contract will be assured).

Shared research and innovative multidisciplinary and multisectoral training by experts and experienced trainers from two sectors (academia and industry) and two research environments (clinic and basic).

A structured training programme consisting of soft skill courses, targeted workshops, retreats, social events and networking.

Secondments at other institutions within the PIPgen consortium.

Gaining experience abroad.

Opportunities for participation in national and international meetings.

Enlarged professional network and improved future scientific career perspective in academia and the private sector.

To apply and for further information on the PIPgen network, please visit www.pipgen.eu

1 First Stage Researcher (R1) PhD candidate or equivalent. Early stage researcher with less than 4 years FTE research experience.

• Research degrees
• Your research options
• Supplementary PhD Programs

Comprehensive Cancer PhD Program

4 Minute read

The Comprehensive Cancer PhD Program is a supplementary learning opportunity to enrich your graduate research experience. The program offers an opportunity to share your research with other disciplines and expand your peer network.

You can find existing Graduate Research courses using our Find a Course search tool.

The Comprehensive Cancer PhD Program provides specialist cancer research training and support for PhD candidates. It complements your core PhD activities.

The program provides a unique opportunity for PhD candidates researching cancer-related topics to work together. It attracts PhD candidates from a range of disciplines.

To be eligible, you must be enrolled as a PhD student in a partner organisation. Together, these organisations form the Victorian Comprehensive Cancer Centre (VCCC) alliance. Through this program, you will experience clinical and research activities across the alliance.

Upon completion, you will be ready to conduct world-class cancer research. The program will also prepare you for a wide range of career options. It does this by broadening the scope of your research knowledge. And by providing professional development and career training programs.

What are the key benefits?

Through the Comprehensive Cancer PhD Program, you will:

• experience clinical and research activities across the ten partners of the VCCC alliance
• understand the bench-to-bedside model. This model is fundamental to the VCCC approach to integrated research.
• enhance your academic progress and stay on track for timely completion of your PhD thesis
• access professional development and career training opportunities. These opportunities will prepare you for a broad range of career options.
• build your CV and give yourself a career advantage. Gain formal recognition of specialist cancer training and professional skills. You will receive a record of participation at the end of your candidature.
• access the Program’s online ‘Community’ resource. You will stay informed of activities. And you can access recordings of past seminars and events.
• network with students who have common research interests, from other organisations in the VCCC alliance.

Who facilitates this program?

• Sir Peter MacCallum Department of Oncology
• University of Melbourne Centre for Cancer Research .

Through the program, you will build your CV and obtain a career advantage. You will have access to a coordinated program of skills, research and career training. This is in addition to your usual PhD activities.

Academic skills development

• Cancer-specific seminars and presentations
• Annual 'Methods in Cancer Research' seminar series
• core technologies
• intellectual property and commercialisation
• good clinical practice
• Annual three-day Thesis Boot Camp. This helps with writing your thesis and submitting it on time.
• Evaluation and discussion of scientific journal articles

Professional and career development

• Topics include networking, leadership, managing your candidature/supervisor, and preparing grant and fellowship applications.
• How to get the most out of a mentoring/coaching relationship.
• Getting help to identify internship and placement opportunities with industry/external groups.

Communication skills development

• preparing conference abstracts and posters
• writing and presentation
• Teaching opportunities, including the supervision of work placement students
• Community engagement activities.

Research seminar series

• Hallmark event for the Comprehensive Cancer PhD Program.
• Annual seminar series delivered in themed blocks of lectures.
• Each theme emphasises the bench-to-bedside model. It incorporates a range of topics from basic, translational and clinical research and impact on clinical outcomes.
• Past topics include: cancer immunology, cancer genetics and genomics, oncogenes and tumour suppressors, and pillars of cancer care.

Student Symposium

• Annual event held by postgraduate student societies. This event showcases student research as oral and poster presentations.

Grand debate

• Annual cancer-themed debate with participants from VCCC alliance organisations.

Chat with a Nobel Laureate

• Annual Q&A-style event with a Nobel Laureate.
• Social events and opportunities to connect with graduate researchers from other organisations. These people may have similar research interests to you.

Participate

To be eligible for this program, you must be:

• working on a cancer-related PhD project
• enrolled at one of the organisations of the VCCC alliance.

Download the program brochure to find out more.

Contact us for more information, or to join the program.

VCCC alliance organisations

• Peter MacCallum Cancer Centre
• The University of Melbourne Centre for Cancer Research
• The Walter and Eliza Hall Institute of Medical Research
• Murdoch Children's Research Institute
• The Royal Melbourne Hospital
• The Royal Children's Hospital Melbourne
• The Royal Women's Hospital
• St Vincent's Hospital Melbourne
• St Vincent's Institute of Medical Research
• Austin Health
• Olivia Newton John Cancer Research Institute
• Western Health
• Victorian Comprehensive Cancer Centre

First published on 21 February 2022.

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Found 31 jobs

Lung cancer researcher – research faculty rush university medical center.

• Chicago, Illinois
• Commensurate with experience
• Rush University

Seeking an investigator with an interest in translational research in the field of lung cancer.

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Global Talent Recruitment of Xinxiang Medical University in 2024

• Yazhouwan National Laboratory, No.8 Huanjin Road
• From CNY5,000,000-10,000,000 according to the requirements of relevant discipline construction.
• Xinxiang Medical University Yazhouwan National Laboratory

Global Talent Recruitment of Xinxiang Medical University in 2024   I.School Profile Xinxiang Medical University (XXMU) is the only independently es...

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Postdoctoral scholar

• San Francisco, California
• UCSF, Neurological Surgery

Postdoctoral scholar position in computational biology at the UCSF Brain Tumor Center

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Faculty Position in Cancer Research

• Farmington, Connecticut (US)
• Not specified
• University of Connecticut Health Center - UCONN

Faculty Position in Cancer Research   University of Connecticut School of Medicine's Carole and Ray Neag Comprehensive Cancer Center is seeking app...

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Assistant Professor to Full Professor

• New Orleans, Louisiana
• Competitive salary + benefits package dependent on candidate's experience and external funding
• LSU Health Sciences Cnter

The LSU LCMC Health Cancer Center, located in New Orleans, LA, is seeking five faculty members at all academic levels.

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Senior Scientist - T Cell Biology (ADC Discovery and Cancer Immunology)

• La Jolla, California
• Competitive

Why Patients Need You Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfill...

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Postdoctoral Fellow - Cancer - Shu-hsia Chen

• Houston, Texas (US)
• Houston Methodist Academic Institute

Overview Postdoctoral positions/research associate/assistant or core staff positions are available to study cancer immune therapies, autoimmune dis...

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Postdoctoral Research Associate

• Oklahoma City, Oklahoma
• University of Oklahoma Health Sciences Center

Postdoctoral Research Associate position at University of Oklahoma Health Sciences Center   The Kamiya Mehla lab at the newly established Departmen...

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Assistant/Associate/Full Professor

• Mountain Home, Tennessee
• East Tennessee University

Invites applications for multiple full-time tenure track open-rank faculty positions.

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Director of Academic Affairs

• Camden, New Jersey (US)
• Depending on Experience
• Coriell Institute for Medical Research

The Director of Academic Affairs is the main administrative resource to advise, support, assist, coordinate, and collaborate on academic initiatives.

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Post-doctoral scholar in cancer biology

• compensation according to years of experience per institutional payscales
• University of California, San Francisco (UCSF)

Postdoctoral position in basic and translational cancer biology at the University of California, San Francisco.

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R&D Clinical Research Manager

• Westbrook, Maine (US)
• Salary range will start at $100,000 based on years and type of experience

The R&D Clinical Research team is hiring two Clinical Research Managers with interests/experience in either biomarker discovery or oncology research.

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Asst/Assoc/Full Professor - Developmental Therapeutics

• Texas Tech University Health Sciences Center, SOM, Cancer Center, Lubbock, TX
• Rank and salary are dependent upon qualifications and experience.
• TTUHSC Cancer Research Center

Asst Professor level tenure-track position in pediatric cancer developmental therapeutics. Preference given to pediatric oncology physician-scientists

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Sr. Medical Director, Prostate Cancer

• La Jolla, California, United States;United States - Washington - BothellCollegeville, Pennsylvania, United States;San Francisco, California, United States;

This position willbe responsible foroverseeing clinical trials and the development strategy for 1 or more medicines in prostate cancer.Reporting to...

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Executive Medical Director, Prostate Cancer

This position willbe responsible foroverseeing clinical trials and the development strategy for multiple medicines in prostate cancer.Reporting to...

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Postdoctoral Scholars – Cancer or Autoimmune Disease

• Los Angeles, California
• University of California, Los Angeles

Postdoctoral positions are available for a PhD or MD with experience in cellular immunology

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Postdoctoral Fellow

• Competitive Salary plus benefits
• Northwestern

Postdoc training position offers an opportunity to work in the NIH-funded lab of Dr. Seth M. Pollack

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Assistant/Associate Professor

• University of Louisville School of Medicine
• University of Louisville, School of Medicine - Microbiology

DEPARTMENT OF MICROBIOLOGY AND IMMUNOLOGY UNIVERSITY of LOUISVILLE TENURE-TRACK FACULTY POSITION

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Vice-President, Cancer Immunology Lead

At Pfizer we deliver Breakthroughs That Change Patients Lives. Discovering new medicines at Pfizer takes teams with a diversity of skills, behavior...

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Assistant or Associate Professor, Cancer Immunology and Immunotherapy

• Baylor College of Medicine

Opening for a tenure-track Assistant or Associate Professor to lead an innovative research effort in tumor antigen discovery,

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Postdoc - Epigenetics and Molecular Pathogenesis

• Burlington, Vermont
• Competative
• University of Vermont

Postdoctoral fellowship starting immediately - chromatin biology, epigenetics, chromatin remodeling, gene transcription and disease pathogenesis

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• Richmond, Virginia
• Salary starts at $53,760.
• Virginia Commonwealth University, Dept of Pharmacology / Toxicology

Postdoctoral fellow position in cancer research

• Baltimore, Maryland (US)
• In accordance with NIH recommendation
• Marlene and Stewart Greenebaum Comprehensive Cancer Center

Postdoctoral Position in Lung Cancer - Baltimore, MD

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Research Scholar - Cancer Research Program

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German Cancer Research Center (DKFZ)

Phd positions in cancer research.

Are you looking for excellent research opportunities for your PhD studies at the forefront of cancer research? The German Cancer Research Center (DKFZ) in Heidelberg invites international students holding a Master’s degree in (molecular) biology, (bio-)chemistry, (bio-)physics, computational biology, computer science, epidemiology/public health studies and related subjects to apply for the International PhD Program.

PhD students are supported by a Thesis Advisory Committee, participate in scientific and professional skills courses, attend international conferences and receive career development support. The language of the PhD program is English. Full funding is provided for the duration of the PhD, either by the DKFZ, third party sources or in collaboration with the DAAD within their Graduate School Scholarship Program.

Research at the DKFZ is organized into the following programs with a lot of interaction and interdisciplinary PhD projects available across different topics:

• Cell Biology and Tumor Biology
• Functional and Structural Genomics
• Cancer Risk Factors and Prevention
• Immunology, Infection and Cancer
• Imaging and Radiooncology

For more information and to apply online visit www.dkfz.de/phd

Do you want to join our lively and international community of over 500 PhD students to do your PhD at Germany’s largest biomedical research institute? Then apply now!

Application Deadline: 15th May 2024

Job details

About the employer.

The German Cancer Research Center (DKFZ) is Germany’s largest biomedical research institute focusing on research against cancer.

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International Programmes 2023/2024

International PhD Programme at the German Cancer Research Center (DKFZ) DKFZ International PhD Programme in Cancer Research

German cancer research center (dkfz) heidelberg • heidelberg.

• Course details
• Costs / Funding
• Requirements / Registration
• About the institution

Working language: English

Doctoral researchers can join the programme anytime.

Summer selection: 15 May Winter selection: 15 December

The DKFZ International PhD Programme in Cancer Research at the German Cancer Research Center (DKFZ) in Heidelberg offers state-of-the-art research opportunities at the forefront of basic, computational, epidemiological, and translational cancer research. DKFZ PhD students receive a doctoral degree from the Biosciences, Medical, or Physics Faculty of the prestigious University of Heidelberg, the oldest university in Germany.

The DKFZ is Germany’s largest biomedical research institute . Around 500 PhD students in over 100 divisions and research groups carry out research to unravel the causes and mechanisms of cancer development and to identify novel tools for diagnosis, treatment, and prevention. In recent years, researchers at the DKFZ have been responsible for major advances both in basic research and in the development of novel methods for clinical application. Two researchers of the DKFZ have been awarded the Nobel Prize , namely Harald zur Hausen in 2008 and Stefan Hell in 2014. As part of the Helmholtz Association, the largest research organisation in Germany, the DKFZ has an international and dynamic work environment and provides its scientists with access to state-of-the-art research facilities.

Research at the DKFZ is highly interdisciplinary , which is reflected by the fact that PhD students have an academic background in (molecular) biology, (bio-)chemistry, (bio-)physics, mathematics, computational biology, computer science, epidemiology/public health studies, and related fields . Projects frequently cross traditional research boundaries and draw upon expertise from multiple scientific and clinical disciplines.

Based on a long tradition of scientific interaction between the DKFZ and the Weizmann Institute of Science (WIS) in Israel, the Graduate School has partnered with the Feinberg Graduate School of the WIS to establish the German-Israeli Helmholtz Research School in Cancer Biology .

For more information, have a look at our website .

The language of the PhD programme is English. Besides receiving supervision from a research group leader, each student has a personal Thesis Advisory Committee . This provides students with further support and advice during the entire duration of the PhD. In addition, PhD students are offered scientific and professional skills courses , lecture series on the current state of cancer research, and career events . Furthermore, they broaden their horizons at PhD retreats and international conferences .

The DKFZ Career Service supports PhD students in planning for a professional future and provides information on different career opportunities. PhD students themselves play a vital role in shaping the programme. They organise many different initiatives and events and are the driving force behind the scientific and social community.

The career prospects after obtaining a PhD from the DKFZ are outstanding. You will find alumni in top positions in academia, industry, and related fields.

• International guest lecturers
• Language training provided
• Training in intercultural skills
• Study trips
• Projects with partners in Germany and abroad
• Helmholtz Graduate Schools

There is no tuition fee at the DKFZ, you will however be required to pay university fees of approx. 190 EUR per semester.

PhD students are fully funded for the duration of the PhD programme.

Applicants from all countries who hold a Master’s degree in a field related to cancer research are invited to apply.

Visit our website for more details on admission requirements .

A language test for English is requested for all applicants except those coming from German-speaking countries (Germany, Austria, Switzerland), as well as native English speakers from Australia, Canada, Ireland, UK, and USA. If your studies were in English, then please upload a PDF document from your university (or Director of Studies) in which this is stated. The following proof of English is accepted:

• TOEFL test with a score of 95+ (internet-based), 240+ (computer-based) or 587+ (paper-based)
• IELTS certificate with a band score 7.0+
• Cambridge Certificate in Advanced English ( CAE )

Please apply via our online application system. The annual application deadlines are 15 May and 15 December. https://www.dkfz.de/en/phd-program/index.html?campaign=phd/daadprog

The DKFZ has a dedicated career service team, which aims to support all PhD students at the DKFZ in planning their professional future. The career service provides:

• career-related workshops and conferences;
• personal career guidance and advise; and
• a career network with DKFZ alumni in academia, industry, and beyond.
• Welcome event
• Buddy programme
• Accompanying programme
• Visa matters
• Specialist counselling

The International Office of the DKFZ provides support for international employees before and after their arrival.

German Cancer Research Center (DKFZ) Heidelberg

The German Cancer Research Center (DKFZ) in Heidelberg is Germany’s largest biomedical research institute. As part of the Helmholtz Association, the largest research organisation in Germany, the DKFZ has an international and dynamic work environment, providing scientists with access to state-of-the-art research facilities and exceptional resources. More than 3,000 employees in over 100 divisions and research groups carry out research to unravel the causes and mechanisms of cancer development and to identify novel tools for diagnosis, treatment, and prevention . Harald zur Hausen (2008) and Stefan Hell (2014) are two researchers of the DKFZ who have been awarded the Nobel Prize. The DKFZ offers attractive prospects and training opportunities for international researchers at all stages of their career.

Heidelberg combines the best of many worlds. With its narrow lanes and ancient buildings, the historic old town immediately transports visitors back into the Middle Ages. Flanked by hills and lush forests, there is plenty to tempt nature-lovers. The gateway to Heidelberg's medieval core is the unmistakable Old Bridge with its two towers. This landmark's nine sandstone arches straddle the Neckar river, whose banks, or Neckarwiese, invite both locals and tourists alike to while away the time.

The city has much to offer the modern-day visitor, including an enviable cultural palette, ranging from theatre and music to film festivals, and even its own beers . Thanks to the presence of many international companies in the region and quality research faculties belonging to the University of Heidelberg, the city is a magnet for cosmopolitan individuals from multicultural backgrounds .

Heidelberg is very much a modern city that prides itself on being at the cutting edge of scientific research . The DKFZ is located in the Neuenheimer Feld, one of the largest biomedical campuses in Germany. This site also hosts the science faculties of Heidelberg University as well as the university hospital and other research departments. DKFZ PhD students may participate in the sports programmes at Heidelberg University.

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Ginny L. Clements Breast Cancer Research Institute

Are you in search of a post-doctoral fellowship in cancer research?

The T32 offers career-making mentorship and transformational training  

For more than 45 years, the University of Arizona Cancer Center has had an invaluable training grant through the National Cancer Institute known as the  T32 .  

This year, the Cancer Center has two T32 openings for postdoctoral fellows with doctoral degrees relevant to cancer prevention and control (CPC) science who are interested in advancing their research program to address cancer prevention and control and cancer related health disparities.  

“The T32 provides fellows with critical protected time to establish a focused research idea and related programming,” said Cancer Center member Cynthia Thomson , PhD, RDN, T32 corresponding principal investigator. “It provides them with specific training opportunities to hone their skills and knowledge. It is also a critical time for developing professional relationships and collaborations to carry their research agenda forward in a meaningful way.”  

Dr. Thomson, a professor in the UArizona College of Public Health, Nutritional Sciences and Wellness, and the BIO5 Institute , was a T32 trainee from 1998-2000 before joining the university faculty.   

She is one of three multiple principal investigators on the T32, including Cancer Center members Robin B. Harris , PhD, MPH, and Terry Badger , PhD, RN.   

The benefits of being a T32 fellow  

The program is a two-year traineeship with exceptional mentors in cancer prevention and control science. Selected fellows engage in innovative research, submit research funding proposals, publish in peer-reviewed scientific journals, and have several opportunities to present their research at scientific conferences around the globe. The program offers preparation for independent cancer prevention academic research careers with a unique population in an environment that addresses health disparities.  

“Mentorship is central to our success,” Dr. Thomson said. “Having a strong mentoring opportunity for the fellow is an important criterion for acceptance into the training program.”  

Each trainee has a primary mentor, responsible for supporting the individual development plan with the student and other secondary or content-specific mentors. Dr. Thomson said the fellows’ primary mentor will be at the university, but others may come from across the U.S. or internationally.  

One example of the program’s success includes former fellow Celina I. Valencia , DrPH, who is now an assistant professor in the UArizona Family and Community Medicine. She is a health equity scientist focused on developing novel methods for measuring the role of social determinants of health on the breast cancer mortality disparity experienced by women from historically marginalized communities in the U.S.  

For her fellowship training, Dr. Valencia’s focused on training in epidemiology and data science analytical approaches to identify and evaluate cancer disparities. Dr. Valencia worked with Dr. Harris as her mentor.  

“They provide a unique and carefully curated scientific training experience that is strategically designed to ensure that the trainee successfully accomplishes their training goal,” said Dr. Valencia of the program’s multiple principal investigators. “Additionally, they provide professional development experiences to ensure that the trainee is well positioned to launch to the next career level.”  

Joining the newest fellows  

Two of the four postdoctoral fellowship positions are already filled. The selected T32 scholars currently in training are Sarah Yeo , PhD, MPP, and Zachary Compton , PhD.  

Dr. Yeo said her research involves elucidating multilevel factors influencing cancer prevention, including modifiable risk factors, cancer screening behaviors, and healthcare access among refugee populations. Her T32 mentor is Cancer Center member Scott Carvajal , PhD, MPH.   

“I selected my mentor because our research interests closely intersected,” she said. “He possesses substantial expertise in health disparities among Hispanic immigrants through community-based participatory research.”  

Dr. Carvajal’s project, “Understanding Ecologic Stress, Risk, and Health Resiliencies in Mexican-Origin Adults Living in a High Poverty Rural Community,” explores factors influencing health outcomes among foreign-born Hispanic immigrants.   

Dr. Yeo said that by collaborating with Dr. Carvajal on this project, she anticipates gaining invaluable insights into cancer prevention among foreign-born immigrants, improving her skills in data analysis, and gaining familiarity with NIH-funded research.  

“Participating in a career development award such as T32 is an accomplishment in itself, which can be perceived favorably by future reviewers,” she said. “More importantly, it offers fellows increased flexibility and autonomy to discern and prioritize their career goals and essential development needs. Additionally, I think that fellows have better access to resources and learning opportunities as they are considered as a significant part of the program.”   

Through his T32 training program, Dr. Compton is developing methods to measure tumor phenotypic plasticity and evolvability as a means of predicting progression in pre-malignant models of oral squamous cell carcinoma.  

His mentor is Carlos Caulin , PhD, associate professor in the UArizona Department of Otolaryngology and director of Translational Head/Neck Cancer Research.  

“Although Dr. Caulin didn’t have any direct experience in my specific line of work, he has so many of the traits a young career scientist should seek out in a mentor,” Dr. Compton said. “I think Dr. Caulin is second to none at the university when it comes to NIH grant writing. He and I have different but matching, foci in our research, and the mentor/mentee relationship is wonderfully complementary.”   

To qualify for the training program, applicants must be a U.S. citizen or permanent resident. Applicants representing diverse groups are encouraged to apply.  

To learn more about applying, complete the T32 Interest Form or email Rebecca Crocker, PhD at [email protected] . View the Cancer Center T32 main page for general information.  

Sealy Center on Aging

utmb.edu/scoa

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Welcome The Sealy Center on Aging at UTMB: Leading Aging Research Since 1995

Quick links.

• Texas Resource Center on Minority Aging Research (RCMAR)
• Claude D. Pepper Older Americans Independence Center (OAIC)
• World Health Organization / Pan Merican Health Organization (WHO/PAHO)
• Center for Comparative Effectiveness Research on Cancer in Texas (CERCIT)
• Health of Older Minorities Training (T32)
• Medical Student Aging Research Training (MSTAR)

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The Sealy Center on Aging focuses on improving the health and well-being of older adults through interdisciplinary research, education, and community service by integrating the resources and activities relevant to aging at UTMB. The Center also implements our research findings in hospitals and clinics, bringing excellence and visibility to our health care system, and improving the health of older adults.

Current Events

University of Texas Medical Branch Sealy Center on Aging (SCoA) 301 University Blvd. Galveston, TX 77555-0177 Directions and Maps Phone: (409) 747-0008 Email: [email protected]

Postdoctoral Fellowship Position

Call for pilot project proposals - utmb dmac cercit.

Call for Pilot Projects - Data Management and Analysis Core for Comparative Effectiveness Research on Cancer in Texas

The UTMB DMAC, funded by the Cancer Prevention and Research Institute of Texas, encourages all investigators in Texas academic and research institutions to submit pilot grant proposals on comparative effectiveness research on cancer in Texas. Proposals from screening, diagnosis, treatment, post-treatment surveillance, or survivorship are all welcome.

Research Programs Supported in part by the Sealy Center on Aging

The Texas Resource Center on Minority Aging Research

Claude d. pepper older americans independence center.

World Health Organization/Pan American Health Organization

Comparative effectiveness research on cancer in texas.

Health of Older Minorities Pre and Postdoctoral Training

Medical student in aging research program.

Rebeca Wong, PhD

Sheridan Lorenz Distinguished Professor in Aging and Health, Professor, Department of Population Health and Health Disparities, School of Public and Population Health; Director, WHO/ PAHO Collaborating Center on Aging and Health; Co-Director, Claude Pepper Older American Independence Center; Director ad interim, Sealy Center on Aging

James S. Goodwin, MD

George and Cynthia Mitchell Distinguished Chair of Geriatric Medicine; Co-director, Claude D Pepper Older Americans Independence Center; Senior Associate Director, Sealy Center on Aging

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