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Scientific Research – Types, Purpose and Guide

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Scientific Research

Scientific Research

Definition:

Scientific research is the systematic and empirical investigation of phenomena, theories, or hypotheses, using various methods and techniques in order to acquire new knowledge or to validate existing knowledge.

It involves the collection, analysis, interpretation, and presentation of data, as well as the formulation and testing of hypotheses. Scientific research can be conducted in various fields, such as natural sciences, social sciences, and engineering, and may involve experiments, observations, surveys, or other forms of data collection. The goal of scientific research is to advance knowledge, improve understanding, and contribute to the development of solutions to practical problems.

Types of Scientific Research

There are different types of scientific research, which can be classified based on their purpose, method, and application. In this response, we will discuss the four main types of scientific research.

Descriptive Research

Descriptive research aims to describe or document a particular phenomenon or situation, without altering it in any way. This type of research is usually done through observation, surveys, or case studies. Descriptive research is useful in generating ideas, understanding complex phenomena, and providing a foundation for future research. However, it does not provide explanations or causal relationships between variables.

Exploratory Research

Exploratory research aims to explore a new area of inquiry or develop initial ideas for future research. This type of research is usually conducted through observation, interviews, or focus groups. Exploratory research is useful in generating hypotheses, identifying research questions, and determining the feasibility of a larger study. However, it does not provide conclusive evidence or establish cause-and-effect relationships.

Experimental Research

Experimental research aims to test cause-and-effect relationships between variables by manipulating one variable and observing the effects on another variable. This type of research involves the use of an experimental group, which receives a treatment, and a control group, which does not receive the treatment. Experimental research is useful in establishing causal relationships, replicating results, and controlling extraneous variables. However, it may not be feasible or ethical to manipulate certain variables in some contexts.

Correlational Research

Correlational research aims to examine the relationship between two or more variables without manipulating them. This type of research involves the use of statistical techniques to determine the strength and direction of the relationship between variables. Correlational research is useful in identifying patterns, predicting outcomes, and testing theories. However, it does not establish causation or control for confounding variables.

Scientific Research Methods

Scientific research methods are used in scientific research to investigate phenomena, acquire knowledge, and answer questions using empirical evidence. Here are some commonly used scientific research methods:

Observational Studies

This method involves observing and recording phenomena as they occur in their natural setting. It can be done through direct observation or by using tools such as cameras, microscopes, or sensors.

Experimental Studies

This method involves manipulating one or more variables to determine the effect on the outcome. This type of study is often used to establish cause-and-effect relationships.

Survey Research

This method involves collecting data from a large number of people by asking them a set of standardized questions. Surveys can be conducted in person, over the phone, or online.

Case Studies

This method involves in-depth analysis of a single individual, group, or organization. Case studies are often used to gain insights into complex or unusual phenomena.

Meta-analysis

This method involves combining data from multiple studies to arrive at a more reliable conclusion. This technique can be used to identify patterns and trends across a large number of studies.

Qualitative Research

This method involves collecting and analyzing non-numerical data, such as interviews, focus groups, or observations. This type of research is often used to explore complex phenomena and to gain an understanding of people’s experiences and perspectives.

Quantitative Research

This method involves collecting and analyzing numerical data using statistical techniques. This type of research is often used to test hypotheses and to establish cause-and-effect relationships.

Longitudinal Studies

This method involves following a group of individuals over a period of time to observe changes and to identify patterns and trends. This type of study can be used to investigate the long-term effects of a particular intervention or exposure.

Data Analysis Methods

There are many different data analysis methods used in scientific research, and the choice of method depends on the type of data being collected and the research question. Here are some commonly used data analysis methods:

  • Descriptive statistics: This involves using summary statistics such as mean, median, mode, standard deviation, and range to describe the basic features of the data.
  • Inferential statistics: This involves using statistical tests to make inferences about a population based on a sample of data. Examples of inferential statistics include t-tests, ANOVA, and regression analysis.
  • Qualitative analysis: This involves analyzing non-numerical data such as interviews, focus groups, and observations. Qualitative analysis may involve identifying themes, patterns, or categories in the data.
  • Content analysis: This involves analyzing the content of written or visual materials such as articles, speeches, or images. Content analysis may involve identifying themes, patterns, or categories in the content.
  • Data mining: This involves using automated methods to analyze large datasets to identify patterns, trends, or relationships in the data.
  • Machine learning: This involves using algorithms to analyze data and make predictions or classifications based on the patterns identified in the data.

Application of Scientific Research

Scientific research has numerous applications in many fields, including:

  • Medicine and healthcare: Scientific research is used to develop new drugs, medical treatments, and vaccines. It is also used to understand the causes and risk factors of diseases, as well as to develop new diagnostic tools and medical devices.
  • Agriculture : Scientific research is used to develop new crop varieties, to improve crop yields, and to develop more sustainable farming practices.
  • Technology and engineering : Scientific research is used to develop new technologies and engineering solutions, such as renewable energy systems, new materials, and advanced manufacturing techniques.
  • Environmental science : Scientific research is used to understand the impacts of human activity on the environment and to develop solutions for mitigating those impacts. It is also used to monitor and manage natural resources, such as water and air quality.
  • Education : Scientific research is used to develop new teaching methods and educational materials, as well as to understand how people learn and develop.
  • Business and economics: Scientific research is used to understand consumer behavior, to develop new products and services, and to analyze economic trends and policies.
  • Social sciences : Scientific research is used to understand human behavior, attitudes, and social dynamics. It is also used to develop interventions to improve social welfare and to inform public policy.

How to Conduct Scientific Research

Conducting scientific research involves several steps, including:

  • Identify a research question: Start by identifying a question or problem that you want to investigate. This question should be clear, specific, and relevant to your field of study.
  • Conduct a literature review: Before starting your research, conduct a thorough review of existing research in your field. This will help you identify gaps in knowledge and develop hypotheses or research questions.
  • Develop a research plan: Once you have a research question, develop a plan for how you will collect and analyze data to answer that question. This plan should include a detailed methodology, a timeline, and a budget.
  • Collect data: Depending on your research question and methodology, you may collect data through surveys, experiments, observations, or other methods.
  • Analyze data: Once you have collected your data, analyze it using appropriate statistical or qualitative methods. This will help you draw conclusions about your research question.
  • Interpret results: Based on your analysis, interpret your results and draw conclusions about your research question. Discuss any limitations or implications of your findings.
  • Communicate results: Finally, communicate your findings to others in your field through presentations, publications, or other means.

Purpose of Scientific Research

The purpose of scientific research is to systematically investigate phenomena, acquire new knowledge, and advance our understanding of the world around us. Scientific research has several key goals, including:

  • Exploring the unknown: Scientific research is often driven by curiosity and the desire to explore uncharted territory. Scientists investigate phenomena that are not well understood, in order to discover new insights and develop new theories.
  • Testing hypotheses: Scientific research involves developing hypotheses or research questions, and then testing them through observation and experimentation. This allows scientists to evaluate the validity of their ideas and refine their understanding of the phenomena they are studying.
  • Solving problems: Scientific research is often motivated by the desire to solve practical problems or address real-world challenges. For example, researchers may investigate the causes of a disease in order to develop new treatments, or explore ways to make renewable energy more affordable and accessible.
  • Advancing knowledge: Scientific research is a collective effort to advance our understanding of the world around us. By building on existing knowledge and developing new insights, scientists contribute to a growing body of knowledge that can be used to inform decision-making, solve problems, and improve our lives.

Examples of Scientific Research

Here are some examples of scientific research that are currently ongoing or have recently been completed:

  • Clinical trials for new treatments: Scientific research in the medical field often involves clinical trials to test new treatments for diseases and conditions. For example, clinical trials may be conducted to evaluate the safety and efficacy of new drugs or medical devices.
  • Genomics research: Scientists are conducting research to better understand the human genome and its role in health and disease. This includes research on genetic mutations that can cause diseases such as cancer, as well as the development of personalized medicine based on an individual’s genetic makeup.
  • Climate change: Scientific research is being conducted to understand the causes and impacts of climate change, as well as to develop solutions for mitigating its effects. This includes research on renewable energy technologies, carbon capture and storage, and sustainable land use practices.
  • Neuroscience : Scientists are conducting research to understand the workings of the brain and the nervous system, with the goal of developing new treatments for neurological disorders such as Alzheimer’s disease and Parkinson’s disease.
  • Artificial intelligence: Researchers are working to develop new algorithms and technologies to improve the capabilities of artificial intelligence systems. This includes research on machine learning, computer vision, and natural language processing.
  • Space exploration: Scientific research is being conducted to explore the cosmos and learn more about the origins of the universe. This includes research on exoplanets, black holes, and the search for extraterrestrial life.

When to use Scientific Research

Some specific situations where scientific research may be particularly useful include:

  • Solving problems: Scientific research can be used to investigate practical problems or address real-world challenges. For example, scientists may investigate the causes of a disease in order to develop new treatments, or explore ways to make renewable energy more affordable and accessible.
  • Decision-making: Scientific research can provide evidence-based information to inform decision-making. For example, policymakers may use scientific research to evaluate the effectiveness of different policy options or to make decisions about public health and safety.
  • Innovation : Scientific research can be used to develop new technologies, products, and processes. For example, research on materials science can lead to the development of new materials with unique properties that can be used in a range of applications.
  • Knowledge creation : Scientific research is an important way of generating new knowledge and advancing our understanding of the world around us. This can lead to new theories, insights, and discoveries that can benefit society.

Advantages of Scientific Research

There are many advantages of scientific research, including:

  • Improved understanding : Scientific research allows us to gain a deeper understanding of the world around us, from the smallest subatomic particles to the largest celestial bodies.
  • Evidence-based decision making: Scientific research provides evidence-based information that can inform decision-making in many fields, from public policy to medicine.
  • Technological advancements: Scientific research drives technological advancements in fields such as medicine, engineering, and materials science. These advancements can improve quality of life, increase efficiency, and reduce costs.
  • New discoveries: Scientific research can lead to new discoveries and breakthroughs that can advance our knowledge in many fields. These discoveries can lead to new theories, technologies, and products.
  • Economic benefits : Scientific research can stimulate economic growth by creating new industries and jobs, and by generating new technologies and products.
  • Improved health outcomes: Scientific research can lead to the development of new medical treatments and technologies that can improve health outcomes and quality of life for people around the world.
  • Increased innovation: Scientific research encourages innovation by promoting collaboration, creativity, and curiosity. This can lead to new and unexpected discoveries that can benefit society.

Limitations of Scientific Research

Scientific research has some limitations that researchers should be aware of. These limitations can include:

  • Research design limitations : The design of a research study can impact the reliability and validity of the results. Poorly designed studies can lead to inaccurate or inconclusive results. Researchers must carefully consider the study design to ensure that it is appropriate for the research question and the population being studied.
  • Sample size limitations: The size of the sample being studied can impact the generalizability of the results. Small sample sizes may not be representative of the larger population, and may lead to incorrect conclusions.
  • Time and resource limitations: Scientific research can be costly and time-consuming. Researchers may not have the resources necessary to conduct a large-scale study, or may not have sufficient time to complete a study with appropriate controls and analysis.
  • Ethical limitations : Certain types of research may raise ethical concerns, such as studies involving human or animal subjects. Ethical concerns may limit the scope of the research that can be conducted, or require additional protocols and procedures to ensure the safety and well-being of participants.
  • Limitations of technology: Technology may limit the types of research that can be conducted, or the accuracy of the data collected. For example, certain types of research may require advanced technology that is not yet available, or may be limited by the accuracy of current measurement tools.
  • Limitations of existing knowledge: Existing knowledge may limit the types of research that can be conducted. For example, if there is limited knowledge in a particular field, it may be difficult to design a study that can provide meaningful results.

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Muhammad Hassan

Researcher, Academic Writer, Web developer

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Articles on Scientific research

Displaying 1 - 20 of 88 articles.

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Julian Koplin , Monash University

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Paul Bierman , University of Vermont and Tammy Rittenour , Utah State University

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Benjamin Allen , University of Southern Queensland

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Daniel Park , Purdue University

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Jenny Whilde , University of Florida and Jessica Alice Farrell , University of Florida

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Oyewale Tomori , Nigerian Academy of Science

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Stephen L Archer , Queen's University, Ontario

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Louise Gentle , Nottingham Trent University

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Anjana Susarla , Michigan State University

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Rees Kassen , L’Université d’Ottawa/University of Ottawa and Ruth Morgan , UCL

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‘Gain of function’ research can create experimental viruses. In light of COVID, it should be more strictly regulated – or banned

Colin D. Butler , Australian National University

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Tara K. Miller , Boston University ; Abe Miller-Rushing , National Park Service , and Richard B. Primack , Boston University

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Cordelia Fine , The University of Melbourne

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Expanding Alzheimer’s research with primates could overcome the problem with treatments that show promise in mice but don’t help humans

Agnès Lacreuse , UMass Amherst ; Allyson J. Bennett , University of Wisconsin-Madison , and Amanda M. Dettmer , Yale University

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Previous Vice President of the Academy of Science of South Africa and DSI-NRF SARChI chair in Fungal Genomics, Professor in Genetics, University of Pretoria, University of Pretoria

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Editor-in-Chief of the South African Journal of Science and Consultant, Vice Principal for Research and Graduate Education, University of Pretoria

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Professor of Public Affairs, The Ohio State University

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Honorary Professor, Australian National University

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Adjunct Professor of Environmental Geography, CQUniversity Australia

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Professor, History & Philosophy of Science program, School of Historical & Philosophical Studies, The University of Melbourne

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Associate Professor, University of Sydney

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Postdoctoral Fellow in Chronobiology, National Institute for Medical Research

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Professor of Medicine, Pharmacology and Biomedical Engineering, University of Illinois Chicago

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Professor of Planetary Science and Astrobiology, Birkbeck, University of London; Honorary Associate Professor, UCL

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Professor of Natural Philosophy in the Department of Physics, University of York

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Professor in High Medieval History, Durham University

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Associate Professor in Experimental Psychology (Perception), University of Oxford

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PhD Student and Trainee Clinical Psychologist at the Graduate Center, City University of New York

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Adjunct Senior Lecturer, University of Tasmania

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Science, health, and public trust.

September 8, 2021

Explaining How Research Works

Understanding Research infographic

We’ve heard “follow the science” a lot during the pandemic. But it seems science has taken us on a long and winding road filled with twists and turns, even changing directions at times. That’s led some people to feel they can’t trust science. But when what we know changes, it often means science is working.

Expaling How Research Works Infographic en español

Explaining the scientific process may be one way that science communicators can help maintain public trust in science. Placing research in the bigger context of its field and where it fits into the scientific process can help people better understand and interpret new findings as they emerge. A single study usually uncovers only a piece of a larger puzzle.

Questions about how the world works are often investigated on many different levels. For example, scientists can look at the different atoms in a molecule, cells in a tissue, or how different tissues or systems affect each other. Researchers often must choose one or a finite number of ways to investigate a question. It can take many different studies using different approaches to start piecing the whole picture together.

Sometimes it might seem like research results contradict each other. But often, studies are just looking at different aspects of the same problem. Researchers can also investigate a question using different techniques or timeframes. That may lead them to arrive at different conclusions from the same data.

Using the data available at the time of their study, scientists develop different explanations, or models. New information may mean that a novel model needs to be developed to account for it. The models that prevail are those that can withstand the test of time and incorporate new information. Science is a constantly evolving and self-correcting process.

Scientists gain more confidence about a model through the scientific process. They replicate each other’s work. They present at conferences. And papers undergo peer review, in which experts in the field review the work before it can be published in scientific journals. This helps ensure that the study is up to current scientific standards and maintains a level of integrity. Peer reviewers may find problems with the experiments or think different experiments are needed to justify the conclusions. They might even offer new ways to interpret the data.

It’s important for science communicators to consider which stage a study is at in the scientific process when deciding whether to cover it. Some studies are posted on preprint servers for other scientists to start weighing in on and haven’t yet been fully vetted. Results that haven't yet been subjected to scientific scrutiny should be reported on with care and context to avoid confusion or frustration from readers.

We’ve developed a one-page guide, "How Research Works: Understanding the Process of Science" to help communicators put the process of science into perspective. We hope it can serve as a useful resource to help explain why science changes—and why it’s important to expect that change. Please take a look and share your thoughts with us by sending an email to  [email protected].

Below are some additional resources:

  • Discoveries in Basic Science: A Perfectly Imperfect Process
  • When Clinical Research Is in the News
  • What is Basic Science and Why is it Important?
  • ​ What is a Research Organism?
  • What Are Clinical Trials and Studies?
  • Basic Research – Digital Media Kit
  • Decoding Science: How Does Science Know What It Knows? (NAS)
  • Can Science Help People Make Decisions ? (NAS)

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Academic Research

Raysonho/ Wikimedia Commons. Academic research can be intense, stimulating, and rewarding. But it is important to know that a research career involves many activities besides research. Scientists spend their time writing applications for funding to do research, as well as writing scientific papers to report the findings of their research. In addition, they spend time presenting their research in oral or poster form to other scientists at group meetings, institutional meetings, and scientific conferences; they also spend time teaching students about their field of study. A scientist's life is often full of tasks that need to be done and most scientists work very hard, but they also love what they do.

Fields of Study

  • Clinical Scientist: David Fredricks
  • Epidemiologist: Gloria Coronado
  • Geneticist: Katie Peichel
  • Clinical Research: Dana Panteleef
  • Research Technician: Nanna Hansen

If you're interested in a general sense in academic research, the first thing to figure out is which field of research is best for you.

The fundamental task of research is asking questions. There are many areas of research in the life sciences, and they generally fall into three categories based on the types of questions that are asked and the tools that are used to answer the questions:

Basic Research

Clinical research, population-based research.

Basic researchers ask questions about how fundamental life processes work. Examples of questions include the following:

  • What are the mechanisms that determine how and when cells divide?
  • How do DNA mutations associated with a disease occur?
  • How and why do cells age?
  • How and why does one type of cell work differently from another type of cell?

Basic researchers usually work in laboratories with other scientists, usually with one faculty member leading a group of postdoctoral fellows, graduate students, and lab technicians who do most of the lab work. The hours can be very long and the work can be challenging, especially for graduate students and postdoctoral fellows. Basic researchers often ask their questions using model organisms, including yeast, worms, flies, fish, and mice.

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  • Faculty Member: Wendy Leisenring

Clinical researchers ask questions about how disease occurs and how it can be cured in humans. Examples of questions include the following:

  • How can we manipulate the body's immune system to improve treatment of a disease?
  • How can we create a drug to improve disease survival?
  • What are the long-term impacts of treatment on quality of life?

Clinical researchers work in laboratories that are very similar to basic researchers, but they often work with human tissue samples to ask their questions. Many clinical researchers find it rewarding to work on a question that may have an impact that they will eventually see come to fruition. At the same time, when you're working with human tissue, you usually have a limited amount of it so the risks of making a mistake that will lose your sample could be high. Clinical researchers will often collaborate with biostatisticians to best design and analyze their studies in order to yield the maximum amount of relevant information.

Population-based research is done by epidemiologists who ask questions to determine how diet, genetics, and lifestyle may influence the risk of disease. They ask these questions in one of two ways:

  • by following a group of people over time and correlating exposure to who gets a disease;
  • by asking a group of people with a disease about their lifestyle and diet choices and comparing the data to a randomly chosen group without the disease in order to look for differences between the two groups.

The types of questions they ask include the following:

  • How can we best prevent teenagers from starting to smoke?
  • Do some genetic variants place a person at greater risk for cancer?
  • Do vitamins help prevent cancer?
  • Does exposure to certain chemicals increase the risk of getting a particular disease?

Epidemiologists also collaborate with biostatisticians in order to design and analyze studies so they can get the most information from them. Rather than work in a lab, epidemiologists often need no more than a desk and computer. However, the interdisciplinary field of molecular epidemiology is changing this, and many epidemiologists ask questions about how a particular gene can influence disease risk, rather than, or in addition to, a lifestyle exposure.

Roles in Research

Faculty member.

Faculty members usually have Ph.D.'s or M.D.'s and have gone through graduate school or medical school followed by several years of being a postdoctoral fellow or medical resident. A faculty member is the leader of their own lab or work group and determines the direction of the research in their group. Most faculty members spend a good deal of their time writing grant proposals and manuscripts, reading research papers, reviewing colleagues' manuscripts and grant proposals, thinking and talking with others about their research to gain new ideas, and mentoring the people in their group.

Faculty positions are usually very competitive to get and are often a result of hard work over many years. However, most faculty members love what they do and wouldn't trade it for anything.

Research Scientist

Shared resource specialist, technician and other support staff, administrative positions.

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What is Scientific Research?

Research study design, natural vs. social science, qualitative vs. quantitative research, more information on qualitative research in the social sciences, acknowledgements.

Thank you to Julie Miller, reference intern, for helping to create this page.

Some people use the term research loosely, for example:

  • People will say they are researching different online websites to find the best place to buy a new appliance or locate a lawn care service.
  • TV news may talk about conducting research when they conduct a viewer poll on current event topic such as an upcoming election.
  • Undergraduate students working on a term paper or project may say they are researching the internet to find information.
  • Private sector companies may say they are conducting research to find a solution for a supply chain holdup.

However, none of the above is considered “scientific research” unless:

  • The research contributes to a body of science by providing new information through ethical study design or
  • The research follows the scientific method, an iterative process of observation and inquiry.

The Scientific Method

  • Make an observation: notice a phenomenon in your life or in society or find a gap in the already published literature.
  • Ask a question about what you have observed.
  • Hypothesize about a potential answer or explanation.
  • Make predictions if our hypothesis is correct.
  • Design an experiment or study that will test your prediction.
  • Test the prediction by conducting an experiment or study; report the outcomes of your study.
  • Iterate! Was your prediction correct? Was the outcome unexpected? Did it lead to new observations?

The scientific method is not separate from the Research Process as described in the rest of this guide, in fact the Research Process is directly related to the observation stage of the scientific method. Understanding what other scientists and researchers have already studied will help you focus your area of study and build on their knowledge.

Designing your experiment or study is important for both natural and social scientists. Sage Research Methods (SRM) has an excellent "Project Planner" that guides you through the basic stages of research design. SRM also has excellent explanations of qualitative and quantitative research methods for the social sciences.

For the natural sciences, Springer Nature Experiments and Protocol Exchange have guidance on quantitative research methods.

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Books, journals, reference books, videos, podcasts, data-sets, and case studies on social science research methods.

Sage Research Methods includes over 2,000 books, reference books, journal articles, videos, datasets, and case studies on all aspects of social science research methodology. Browse the methods map or the list of methods to identify a social science method to pursue further. Includes a project planning tool and the "Which Stats Test" tool to identify the best statistical method for your project. Includes the notable "little green book" series (Quantitative Applications in the Social Sciences) and the "little blue book" series (Qualitative Research Methods).

Platform connecting researchers with protocols and methods.

Springer Nature Experiments has been designed to help users/researchers find and evaluate relevant protocols and methods across the whole Springer Nature protocols and methods portfolio using one search. This database includes:

  • Nature Protocols
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Open access for all users

Open repository for sharing scientific research protocols. These protocols are posted directly on the Protocol Exchange by authors and are made freely available to the scientific community for use and comment.

Includes these topics:

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Qualitative research is primarily exploratory. It is used to gain an understanding of underlying reasons, opinions, and motivations. Qualitative research is also used to uncover trends in thought and opinions and to dive deeper into a problem by studying an individual or a group.

Qualitative methods usually use unstructured or semi-structured techniques. The sample size is typically smaller than in quantitative research.

Example: interviews and focus groups.

Quantitative research is characterized by the gathering of data with the aim of testing a hypothesis. The data generated are numerical, or, if not numerical, can be transformed into useable statistics.

Quantitative data collection methods are more structured than qualitative data collection methods and sample sizes are usually larger.

Example: survey

Note: The above descriptions of qualitative and quantitative research are mainly for research in the Social Sciences, rather than for Natural Sciences as most natural sciences rely on quantitative methods for their experiments.

Qualitative research is approaching the world in its natural setting and in a way that reveals the particularities rather than doing studies in a controlled setting. It aims to understand, describe, and sometimes explain social phenomena in a number of different ways:

  • Experiences of individuals or groups
  • Interactions and communications
  • Documents (texts, images, film, or sounds, and digital documents)
  • Experiences or interactions

Qualitative researchers seek to understand how people conceptualize the world around them, what they are doing, how they are doing it or what is happening to them in terms that are significant and that offer meaningful learnings.

Qualitative researchers develop and refine concepts (or hypotheses, if they are used) in the process of research and of collecting data. Cases (its history and complexity) are an important context for understanding the issue that is studied. A major part of qualitative research is based on text and writing – from field notes and transcripts to descriptions and interpretations and finally to the presentation of the findings and of the research as a whole.

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What Is Research, and Why Do People Do It?

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  • James Hiebert 6 ,
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  • Charles Hohensee 6  

Part of the book series: Research in Mathematics Education ((RME))

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Abstractspiepr Abs1

Every day people do research as they gather information to learn about something of interest. In the scientific world, however, research means something different than simply gathering information. Scientific research is characterized by its careful planning and observing, by its relentless efforts to understand and explain, and by its commitment to learn from everyone else seriously engaged in research. We call this kind of research scientific inquiry and define it as “formulating, testing, and revising hypotheses.” By “hypotheses” we do not mean the hypotheses you encounter in statistics courses. We mean predictions about what you expect to find and rationales for why you made these predictions. Throughout this and the remaining chapters we make clear that the process of scientific inquiry applies to all kinds of research studies and data, both qualitative and quantitative.

You have full access to this open access chapter,  Download chapter PDF

Part I. What Is Research?

Have you ever studied something carefully because you wanted to know more about it? Maybe you wanted to know more about your grandmother’s life when she was younger so you asked her to tell you stories from her childhood, or maybe you wanted to know more about a fertilizer you were about to use in your garden so you read the ingredients on the package and looked them up online. According to the dictionary definition, you were doing research.

Recall your high school assignments asking you to “research” a topic. The assignment likely included consulting a variety of sources that discussed the topic, perhaps including some “original” sources. Often, the teacher referred to your product as a “research paper.”

Were you conducting research when you interviewed your grandmother or wrote high school papers reviewing a particular topic? Our view is that you were engaged in part of the research process, but only a small part. In this book, we reserve the word “research” for what it means in the scientific world, that is, for scientific research or, more pointedly, for scientific inquiry .

Exercise 1.1

Before you read any further, write a definition of what you think scientific inquiry is. Keep it short—Two to three sentences. You will periodically update this definition as you read this chapter and the remainder of the book.

This book is about scientific inquiry—what it is and how to do it. For starters, scientific inquiry is a process, a particular way of finding out about something that involves a number of phases. Each phase of the process constitutes one aspect of scientific inquiry. You are doing scientific inquiry as you engage in each phase, but you have not done scientific inquiry until you complete the full process. Each phase is necessary but not sufficient.

In this chapter, we set the stage by defining scientific inquiry—describing what it is and what it is not—and by discussing what it is good for and why people do it. The remaining chapters build directly on the ideas presented in this chapter.

A first thing to know is that scientific inquiry is not all or nothing. “Scientificness” is a continuum. Inquiries can be more scientific or less scientific. What makes an inquiry more scientific? You might be surprised there is no universally agreed upon answer to this question. None of the descriptors we know of are sufficient by themselves to define scientific inquiry. But all of them give you a way of thinking about some aspects of the process of scientific inquiry. Each one gives you different insights.

An image of the book's description with the words like research, science, and inquiry and what the word research meant in the scientific world.

Exercise 1.2

As you read about each descriptor below, think about what would make an inquiry more or less scientific. If you think a descriptor is important, use it to revise your definition of scientific inquiry.

Creating an Image of Scientific Inquiry

We will present three descriptors of scientific inquiry. Each provides a different perspective and emphasizes a different aspect of scientific inquiry. We will draw on all three descriptors to compose our definition of scientific inquiry.

Descriptor 1. Experience Carefully Planned in Advance

Sir Ronald Fisher, often called the father of modern statistical design, once referred to research as “experience carefully planned in advance” (1935, p. 8). He said that humans are always learning from experience, from interacting with the world around them. Usually, this learning is haphazard rather than the result of a deliberate process carried out over an extended period of time. Research, Fisher said, was learning from experience, but experience carefully planned in advance.

This phrase can be fully appreciated by looking at each word. The fact that scientific inquiry is based on experience means that it is based on interacting with the world. These interactions could be thought of as the stuff of scientific inquiry. In addition, it is not just any experience that counts. The experience must be carefully planned . The interactions with the world must be conducted with an explicit, describable purpose, and steps must be taken to make the intended learning as likely as possible. This planning is an integral part of scientific inquiry; it is not just a preparation phase. It is one of the things that distinguishes scientific inquiry from many everyday learning experiences. Finally, these steps must be taken beforehand and the purpose of the inquiry must be articulated in advance of the experience. Clearly, scientific inquiry does not happen by accident, by just stumbling into something. Stumbling into something unexpected and interesting can happen while engaged in scientific inquiry, but learning does not depend on it and serendipity does not make the inquiry scientific.

Descriptor 2. Observing Something and Trying to Explain Why It Is the Way It Is

When we were writing this chapter and googled “scientific inquiry,” the first entry was: “Scientific inquiry refers to the diverse ways in which scientists study the natural world and propose explanations based on the evidence derived from their work.” The emphasis is on studying, or observing, and then explaining . This descriptor takes the image of scientific inquiry beyond carefully planned experience and includes explaining what was experienced.

According to the Merriam-Webster dictionary, “explain” means “(a) to make known, (b) to make plain or understandable, (c) to give the reason or cause of, and (d) to show the logical development or relations of” (Merriam-Webster, n.d. ). We will use all these definitions. Taken together, they suggest that to explain an observation means to understand it by finding reasons (or causes) for why it is as it is. In this sense of scientific inquiry, the following are synonyms: explaining why, understanding why, and reasoning about causes and effects. Our image of scientific inquiry now includes planning, observing, and explaining why.

An image represents the observation required in the scientific inquiry including planning and explaining.

We need to add a final note about this descriptor. We have phrased it in a way that suggests “observing something” means you are observing something in real time—observing the way things are or the way things are changing. This is often true. But, observing could mean observing data that already have been collected, maybe by someone else making the original observations (e.g., secondary analysis of NAEP data or analysis of existing video recordings of classroom instruction). We will address secondary analyses more fully in Chap. 4 . For now, what is important is that the process requires explaining why the data look like they do.

We must note that for us, the term “data” is not limited to numerical or quantitative data such as test scores. Data can also take many nonquantitative forms, including written survey responses, interview transcripts, journal entries, video recordings of students, teachers, and classrooms, text messages, and so forth.

An image represents the data explanation as it is not limited and takes numerous non-quantitative forms including an interview, journal entries, etc.

Exercise 1.3

What are the implications of the statement that just “observing” is not enough to count as scientific inquiry? Does this mean that a detailed description of a phenomenon is not scientific inquiry?

Find sources that define research in education that differ with our position, that say description alone, without explanation, counts as scientific research. Identify the precise points where the opinions differ. What are the best arguments for each of the positions? Which do you prefer? Why?

Descriptor 3. Updating Everyone’s Thinking in Response to More and Better Information

This descriptor focuses on a third aspect of scientific inquiry: updating and advancing the field’s understanding of phenomena that are investigated. This descriptor foregrounds a powerful characteristic of scientific inquiry: the reliability (or trustworthiness) of what is learned and the ultimate inevitability of this learning to advance human understanding of phenomena. Humans might choose not to learn from scientific inquiry, but history suggests that scientific inquiry always has the potential to advance understanding and that, eventually, humans take advantage of these new understandings.

Before exploring these bold claims a bit further, note that this descriptor uses “information” in the same way the previous two descriptors used “experience” and “observations.” These are the stuff of scientific inquiry and we will use them often, sometimes interchangeably. Frequently, we will use the term “data” to stand for all these terms.

An overriding goal of scientific inquiry is for everyone to learn from what one scientist does. Much of this book is about the methods you need to use so others have faith in what you report and can learn the same things you learned. This aspect of scientific inquiry has many implications.

One implication is that scientific inquiry is not a private practice. It is a public practice available for others to see and learn from. Notice how different this is from everyday learning. When you happen to learn something from your everyday experience, often only you gain from the experience. The fact that research is a public practice means it is also a social one. It is best conducted by interacting with others along the way: soliciting feedback at each phase, taking opportunities to present work-in-progress, and benefitting from the advice of others.

A second implication is that you, as the researcher, must be committed to sharing what you are doing and what you are learning in an open and transparent way. This allows all phases of your work to be scrutinized and critiqued. This is what gives your work credibility. The reliability or trustworthiness of your findings depends on your colleagues recognizing that you have used all appropriate methods to maximize the chances that your claims are justified by the data.

A third implication of viewing scientific inquiry as a collective enterprise is the reverse of the second—you must be committed to receiving comments from others. You must treat your colleagues as fair and honest critics even though it might sometimes feel otherwise. You must appreciate their job, which is to remain skeptical while scrutinizing what you have done in considerable detail. To provide the best help to you, they must remain skeptical about your conclusions (when, for example, the data are difficult for them to interpret) until you offer a convincing logical argument based on the information you share. A rather harsh but good-to-remember statement of the role of your friendly critics was voiced by Karl Popper, a well-known twentieth century philosopher of science: “. . . if you are interested in the problem which I tried to solve by my tentative assertion, you may help me by criticizing it as severely as you can” (Popper, 1968, p. 27).

A final implication of this third descriptor is that, as someone engaged in scientific inquiry, you have no choice but to update your thinking when the data support a different conclusion. This applies to your own data as well as to those of others. When data clearly point to a specific claim, even one that is quite different than you expected, you must reconsider your position. If the outcome is replicated multiple times, you need to adjust your thinking accordingly. Scientific inquiry does not let you pick and choose which data to believe; it mandates that everyone update their thinking when the data warrant an update.

Doing Scientific Inquiry

We define scientific inquiry in an operational sense—what does it mean to do scientific inquiry? What kind of process would satisfy all three descriptors: carefully planning an experience in advance; observing and trying to explain what you see; and, contributing to updating everyone’s thinking about an important phenomenon?

We define scientific inquiry as formulating , testing , and revising hypotheses about phenomena of interest.

Of course, we are not the only ones who define it in this way. The definition for the scientific method posted by the editors of Britannica is: “a researcher develops a hypothesis, tests it through various means, and then modifies the hypothesis on the basis of the outcome of the tests and experiments” (Britannica, n.d. ).

An image represents the scientific inquiry definition given by the editors of Britannica and also defines the hypothesis on the basis of the experiments.

Notice how defining scientific inquiry this way satisfies each of the descriptors. “Carefully planning an experience in advance” is exactly what happens when formulating a hypothesis about a phenomenon of interest and thinking about how to test it. “ Observing a phenomenon” occurs when testing a hypothesis, and “ explaining ” what is found is required when revising a hypothesis based on the data. Finally, “updating everyone’s thinking” comes from comparing publicly the original with the revised hypothesis.

Doing scientific inquiry, as we have defined it, underscores the value of accumulating knowledge rather than generating random bits of knowledge. Formulating, testing, and revising hypotheses is an ongoing process, with each revised hypothesis begging for another test, whether by the same researcher or by new researchers. The editors of Britannica signaled this cyclic process by adding the following phrase to their definition of the scientific method: “The modified hypothesis is then retested, further modified, and tested again.” Scientific inquiry creates a process that encourages each study to build on the studies that have gone before. Through collective engagement in this process of building study on top of study, the scientific community works together to update its thinking.

Before exploring more fully the meaning of “formulating, testing, and revising hypotheses,” we need to acknowledge that this is not the only way researchers define research. Some researchers prefer a less formal definition, one that includes more serendipity, less planning, less explanation. You might have come across more open definitions such as “research is finding out about something.” We prefer the tighter hypothesis formulation, testing, and revision definition because we believe it provides a single, coherent map for conducting research that addresses many of the thorny problems educational researchers encounter. We believe it is the most useful orientation toward research and the most helpful to learn as a beginning researcher.

A final clarification of our definition is that it applies equally to qualitative and quantitative research. This is a familiar distinction in education that has generated much discussion. You might think our definition favors quantitative methods over qualitative methods because the language of hypothesis formulation and testing is often associated with quantitative methods. In fact, we do not favor one method over another. In Chap. 4 , we will illustrate how our definition fits research using a range of quantitative and qualitative methods.

Exercise 1.4

Look for ways to extend what the field knows in an area that has already received attention by other researchers. Specifically, you can search for a program of research carried out by more experienced researchers that has some revised hypotheses that remain untested. Identify a revised hypothesis that you might like to test.

Unpacking the Terms Formulating, Testing, and Revising Hypotheses

To get a full sense of the definition of scientific inquiry we will use throughout this book, it is helpful to spend a little time with each of the key terms.

We first want to make clear that we use the term “hypothesis” as it is defined in most dictionaries and as it used in many scientific fields rather than as it is usually defined in educational statistics courses. By “hypothesis,” we do not mean a null hypothesis that is accepted or rejected by statistical analysis. Rather, we use “hypothesis” in the sense conveyed by the following definitions: “An idea or explanation for something that is based on known facts but has not yet been proved” (Cambridge University Press, n.d. ), and “An unproved theory, proposition, or supposition, tentatively accepted to explain certain facts and to provide a basis for further investigation or argument” (Agnes & Guralnik, 2008 ).

We distinguish two parts to “hypotheses.” Hypotheses consist of predictions and rationales . Predictions are statements about what you expect to find when you inquire about something. Rationales are explanations for why you made the predictions you did, why you believe your predictions are correct. So, for us “formulating hypotheses” means making explicit predictions and developing rationales for the predictions.

“Testing hypotheses” means making observations that allow you to assess in what ways your predictions were correct and in what ways they were incorrect. In education research, it is rarely useful to think of your predictions as either right or wrong. Because of the complexity of most issues you will investigate, most predictions will be right in some ways and wrong in others.

By studying the observations you make (data you collect) to test your hypotheses, you can revise your hypotheses to better align with the observations. This means revising your predictions plus revising your rationales to justify your adjusted predictions. Even though you might not run another test, formulating revised hypotheses is an essential part of conducting a research study. Comparing your original and revised hypotheses informs everyone of what you learned by conducting your study. In addition, a revised hypothesis sets the stage for you or someone else to extend your study and accumulate more knowledge of the phenomenon.

We should note that not everyone makes a clear distinction between predictions and rationales as two aspects of hypotheses. In fact, common, non-scientific uses of the word “hypothesis” may limit it to only a prediction or only an explanation (or rationale). We choose to explicitly include both prediction and rationale in our definition of hypothesis, not because we assert this should be the universal definition, but because we want to foreground the importance of both parts acting in concert. Using “hypothesis” to represent both prediction and rationale could hide the two aspects, but we make them explicit because they provide different kinds of information. It is usually easier to make predictions than develop rationales because predictions can be guesses, hunches, or gut feelings about which you have little confidence. Developing a compelling rationale requires careful thought plus reading what other researchers have found plus talking with your colleagues. Often, while you are developing your rationale you will find good reasons to change your predictions. Developing good rationales is the engine that drives scientific inquiry. Rationales are essentially descriptions of how much you know about the phenomenon you are studying. Throughout this guide, we will elaborate on how developing good rationales drives scientific inquiry. For now, we simply note that it can sharpen your predictions and help you to interpret your data as you test your hypotheses.

An image represents the rationale and the prediction for the scientific inquiry and different types of information provided by the terms.

Hypotheses in education research take a variety of forms or types. This is because there are a variety of phenomena that can be investigated. Investigating educational phenomena is sometimes best done using qualitative methods, sometimes using quantitative methods, and most often using mixed methods (e.g., Hay, 2016 ; Weis et al. 2019a ; Weisner, 2005 ). This means that, given our definition, hypotheses are equally applicable to qualitative and quantitative investigations.

Hypotheses take different forms when they are used to investigate different kinds of phenomena. Two very different activities in education could be labeled conducting experiments and descriptions. In an experiment, a hypothesis makes a prediction about anticipated changes, say the changes that occur when a treatment or intervention is applied. You might investigate how students’ thinking changes during a particular kind of instruction.

A second type of hypothesis, relevant for descriptive research, makes a prediction about what you will find when you investigate and describe the nature of a situation. The goal is to understand a situation as it exists rather than to understand a change from one situation to another. In this case, your prediction is what you expect to observe. Your rationale is the set of reasons for making this prediction; it is your current explanation for why the situation will look like it does.

You will probably read, if you have not already, that some researchers say you do not need a prediction to conduct a descriptive study. We will discuss this point of view in Chap. 2 . For now, we simply claim that scientific inquiry, as we have defined it, applies to all kinds of research studies. Descriptive studies, like others, not only benefit from formulating, testing, and revising hypotheses, but also need hypothesis formulating, testing, and revising.

One reason we define research as formulating, testing, and revising hypotheses is that if you think of research in this way you are less likely to go wrong. It is a useful guide for the entire process, as we will describe in detail in the chapters ahead. For example, as you build the rationale for your predictions, you are constructing the theoretical framework for your study (Chap. 3 ). As you work out the methods you will use to test your hypothesis, every decision you make will be based on asking, “Will this help me formulate or test or revise my hypothesis?” (Chap. 4 ). As you interpret the results of testing your predictions, you will compare them to what you predicted and examine the differences, focusing on how you must revise your hypotheses (Chap. 5 ). By anchoring the process to formulating, testing, and revising hypotheses, you will make smart decisions that yield a coherent and well-designed study.

Exercise 1.5

Compare the concept of formulating, testing, and revising hypotheses with the descriptions of scientific inquiry contained in Scientific Research in Education (NRC, 2002 ). How are they similar or different?

Exercise 1.6

Provide an example to illustrate and emphasize the differences between everyday learning/thinking and scientific inquiry.

Learning from Doing Scientific Inquiry

We noted earlier that a measure of what you have learned by conducting a research study is found in the differences between your original hypothesis and your revised hypothesis based on the data you collected to test your hypothesis. We will elaborate this statement in later chapters, but we preview our argument here.

Even before collecting data, scientific inquiry requires cycles of making a prediction, developing a rationale, refining your predictions, reading and studying more to strengthen your rationale, refining your predictions again, and so forth. And, even if you have run through several such cycles, you still will likely find that when you test your prediction you will be partly right and partly wrong. The results will support some parts of your predictions but not others, or the results will “kind of” support your predictions. A critical part of scientific inquiry is making sense of your results by interpreting them against your predictions. Carefully describing what aspects of your data supported your predictions, what aspects did not, and what data fell outside of any predictions is not an easy task, but you cannot learn from your study without doing this analysis.

An image represents the cycle of events that take place before making predictions, developing the rationale, and studying the prediction and rationale multiple times.

Analyzing the matches and mismatches between your predictions and your data allows you to formulate different rationales that would have accounted for more of the data. The best revised rationale is the one that accounts for the most data. Once you have revised your rationales, you can think about the predictions they best justify or explain. It is by comparing your original rationales to your new rationales that you can sort out what you learned from your study.

Suppose your study was an experiment. Maybe you were investigating the effects of a new instructional intervention on students’ learning. Your original rationale was your explanation for why the intervention would change the learning outcomes in a particular way. Your revised rationale explained why the changes that you observed occurred like they did and why your revised predictions are better. Maybe your original rationale focused on the potential of the activities if they were implemented in ideal ways and your revised rationale included the factors that are likely to affect how teachers implement them. By comparing the before and after rationales, you are describing what you learned—what you can explain now that you could not before. Another way of saying this is that you are describing how much more you understand now than before you conducted your study.

Revised predictions based on carefully planned and collected data usually exhibit some of the following features compared with the originals: more precision, more completeness, and broader scope. Revised rationales have more explanatory power and become more complete, more aligned with the new predictions, sharper, and overall more convincing.

Part II. Why Do Educators Do Research?

Doing scientific inquiry is a lot of work. Each phase of the process takes time, and you will often cycle back to improve earlier phases as you engage in later phases. Because of the significant effort required, you should make sure your study is worth it. So, from the beginning, you should think about the purpose of your study. Why do you want to do it? And, because research is a social practice, you should also think about whether the results of your study are likely to be important and significant to the education community.

If you are doing research in the way we have described—as scientific inquiry—then one purpose of your study is to understand , not just to describe or evaluate or report. As we noted earlier, when you formulate hypotheses, you are developing rationales that explain why things might be like they are. In our view, trying to understand and explain is what separates research from other kinds of activities, like evaluating or describing.

One reason understanding is so important is that it allows researchers to see how or why something works like it does. When you see how something works, you are better able to predict how it might work in other contexts, under other conditions. And, because conditions, or contextual factors, matter a lot in education, gaining insights into applying your findings to other contexts increases the contributions of your work and its importance to the broader education community.

Consequently, the purposes of research studies in education often include the more specific aim of identifying and understanding the conditions under which the phenomena being studied work like the observations suggest. A classic example of this kind of study in mathematics education was reported by William Brownell and Harold Moser in 1949 . They were trying to establish which method of subtracting whole numbers could be taught most effectively—the regrouping method or the equal additions method. However, they realized that effectiveness might depend on the conditions under which the methods were taught—“meaningfully” versus “mechanically.” So, they designed a study that crossed the two instructional approaches with the two different methods (regrouping and equal additions). Among other results, they found that these conditions did matter. The regrouping method was more effective under the meaningful condition than the mechanical condition, but the same was not true for the equal additions algorithm.

What do education researchers want to understand? In our view, the ultimate goal of education is to offer all students the best possible learning opportunities. So, we believe the ultimate purpose of scientific inquiry in education is to develop understanding that supports the improvement of learning opportunities for all students. We say “ultimate” because there are lots of issues that must be understood to improve learning opportunities for all students. Hypotheses about many aspects of education are connected, ultimately, to students’ learning. For example, formulating and testing a hypothesis that preservice teachers need to engage in particular kinds of activities in their coursework in order to teach particular topics well is, ultimately, connected to improving students’ learning opportunities. So is hypothesizing that school districts often devote relatively few resources to instructional leadership training or hypothesizing that positioning mathematics as a tool students can use to combat social injustice can help students see the relevance of mathematics to their lives.

We do not exclude the importance of research on educational issues more removed from improving students’ learning opportunities, but we do think the argument for their importance will be more difficult to make. If there is no way to imagine a connection between your hypothesis and improving learning opportunities for students, even a distant connection, we recommend you reconsider whether it is an important hypothesis within the education community.

Notice that we said the ultimate goal of education is to offer all students the best possible learning opportunities. For too long, educators have been satisfied with a goal of offering rich learning opportunities for lots of students, sometimes even for just the majority of students, but not necessarily for all students. Evaluations of success often are based on outcomes that show high averages. In other words, if many students have learned something, or even a smaller number have learned a lot, educators may have been satisfied. The problem is that there is usually a pattern in the groups of students who receive lower quality opportunities—students of color and students who live in poor areas, urban and rural. This is not acceptable. Consequently, we emphasize the premise that the purpose of education research is to offer rich learning opportunities to all students.

One way to make sure you will be able to convince others of the importance of your study is to consider investigating some aspect of teachers’ shared instructional problems. Historically, researchers in education have set their own research agendas, regardless of the problems teachers are facing in schools. It is increasingly recognized that teachers have had trouble applying to their own classrooms what researchers find. To address this problem, a researcher could partner with a teacher—better yet, a small group of teachers—and talk with them about instructional problems they all share. These discussions can create a rich pool of problems researchers can consider. If researchers pursued one of these problems (preferably alongside teachers), the connection to improving learning opportunities for all students could be direct and immediate. “Grounding a research question in instructional problems that are experienced across multiple teachers’ classrooms helps to ensure that the answer to the question will be of sufficient scope to be relevant and significant beyond the local context” (Cai et al., 2019b , p. 115).

As a beginning researcher, determining the relevance and importance of a research problem is especially challenging. We recommend talking with advisors, other experienced researchers, and peers to test the educational importance of possible research problems and topics of study. You will also learn much more about the issue of research importance when you read Chap. 5 .

Exercise 1.7

Identify a problem in education that is closely connected to improving learning opportunities and a problem that has a less close connection. For each problem, write a brief argument (like a logical sequence of if-then statements) that connects the problem to all students’ learning opportunities.

Part III. Conducting Research as a Practice of Failing Productively

Scientific inquiry involves formulating hypotheses about phenomena that are not fully understood—by you or anyone else. Even if you are able to inform your hypotheses with lots of knowledge that has already been accumulated, you are likely to find that your prediction is not entirely accurate. This is normal. Remember, scientific inquiry is a process of constantly updating your thinking. More and better information means revising your thinking, again, and again, and again. Because you never fully understand a complicated phenomenon and your hypotheses never produce completely accurate predictions, it is easy to believe you are somehow failing.

The trick is to fail upward, to fail to predict accurately in ways that inform your next hypothesis so you can make a better prediction. Some of the best-known researchers in education have been open and honest about the many times their predictions were wrong and, based on the results of their studies and those of others, they continuously updated their thinking and changed their hypotheses.

A striking example of publicly revising (actually reversing) hypotheses due to incorrect predictions is found in the work of Lee J. Cronbach, one of the most distinguished educational psychologists of the twentieth century. In 1955, Cronbach delivered his presidential address to the American Psychological Association. Titling it “Two Disciplines of Scientific Psychology,” Cronbach proposed a rapprochement between two research approaches—correlational studies that focused on individual differences and experimental studies that focused on instructional treatments controlling for individual differences. (We will examine different research approaches in Chap. 4 ). If these approaches could be brought together, reasoned Cronbach ( 1957 ), researchers could find interactions between individual characteristics and treatments (aptitude-treatment interactions or ATIs), fitting the best treatments to different individuals.

In 1975, after years of research by many researchers looking for ATIs, Cronbach acknowledged the evidence for simple, useful ATIs had not been found. Even when trying to find interactions between a few variables that could provide instructional guidance, the analysis, said Cronbach, creates “a hall of mirrors that extends to infinity, tormenting even the boldest investigators and defeating even ambitious designs” (Cronbach, 1975 , p. 119).

As he was reflecting back on his work, Cronbach ( 1986 ) recommended moving away from documenting instructional effects through statistical inference (an approach he had championed for much of his career) and toward approaches that probe the reasons for these effects, approaches that provide a “full account of events in a time, place, and context” (Cronbach, 1986 , p. 104). This is a remarkable change in hypotheses, a change based on data and made fully transparent. Cronbach understood the value of failing productively.

Closer to home, in a less dramatic example, one of us began a line of scientific inquiry into how to prepare elementary preservice teachers to teach early algebra. Teaching early algebra meant engaging elementary students in early forms of algebraic reasoning. Such reasoning should help them transition from arithmetic to algebra. To begin this line of inquiry, a set of activities for preservice teachers were developed. Even though the activities were based on well-supported hypotheses, they largely failed to engage preservice teachers as predicted because of unanticipated challenges the preservice teachers faced. To capitalize on this failure, follow-up studies were conducted, first to better understand elementary preservice teachers’ challenges with preparing to teach early algebra, and then to better support preservice teachers in navigating these challenges. In this example, the initial failure was a necessary step in the researchers’ scientific inquiry and furthered the researchers’ understanding of this issue.

We present another example of failing productively in Chap. 2 . That example emerges from recounting the history of a well-known research program in mathematics education.

Making mistakes is an inherent part of doing scientific research. Conducting a study is rarely a smooth path from beginning to end. We recommend that you keep the following things in mind as you begin a career of conducting research in education.

First, do not get discouraged when you make mistakes; do not fall into the trap of feeling like you are not capable of doing research because you make too many errors.

Second, learn from your mistakes. Do not ignore your mistakes or treat them as errors that you simply need to forget and move past. Mistakes are rich sites for learning—in research just as in other fields of study.

Third, by reflecting on your mistakes, you can learn to make better mistakes, mistakes that inform you about a productive next step. You will not be able to eliminate your mistakes, but you can set a goal of making better and better mistakes.

Exercise 1.8

How does scientific inquiry differ from everyday learning in giving you the tools to fail upward? You may find helpful perspectives on this question in other resources on science and scientific inquiry (e.g., Failure: Why Science is So Successful by Firestein, 2015).

Exercise 1.9

Use what you have learned in this chapter to write a new definition of scientific inquiry. Compare this definition with the one you wrote before reading this chapter. If you are reading this book as part of a course, compare your definition with your colleagues’ definitions. Develop a consensus definition with everyone in the course.

Part IV. Preview of Chap. 2

Now that you have a good idea of what research is, at least of what we believe research is, the next step is to think about how to actually begin doing research. This means how to begin formulating, testing, and revising hypotheses. As for all phases of scientific inquiry, there are lots of things to think about. Because it is critical to start well, we devote Chap. 2 to getting started with formulating hypotheses.

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Hiebert, J., Cai, J., Hwang, S., Morris, A.K., Hohensee, C. (2023). What Is Research, and Why Do People Do It?. In: Doing Research: A New Researcher’s Guide. Research in Mathematics Education. Springer, Cham. https://doi.org/10.1007/978-3-031-19078-0_1

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This guide provides an overview of research methods, how to choose and use them, and supports and resources at UC Berkeley. 

As Patten and Newhart note in the book Understanding Research Methods , "Research methods are the building blocks of the scientific enterprise. They are the "how" for building systematic knowledge. The accumulation of knowledge through research is by its nature a collective endeavor. Each well-designed study provides evidence that may support, amend, refute, or deepen the understanding of existing knowledge...Decisions are important throughout the practice of research and are designed to help researchers collect evidence that includes the full spectrum of the phenomenon under study, to maintain logical rules, and to mitigate or account for possible sources of bias. In many ways, learning research methods is learning how to see and make these decisions."

The choice of methods varies by discipline, by the kind of phenomenon being studied and the data being used to study it, by the technology available, and more.  This guide is an introduction, but if you don't see what you need here, always contact your subject librarian, and/or take a look to see if there's a library research guide that will answer your question. 

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START HERE: SAGE Research Methods

Without question, the most comprehensive resource available from the library is SAGE Research Methods.  HERE IS THE ONLINE GUIDE  to this one-stop shopping collection, and some helpful links are below:

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  • What Is a Research Design | Types, Guide & Examples

What Is a Research Design | Types, Guide & Examples

Published on June 7, 2021 by Shona McCombes . Revised on November 20, 2023 by Pritha Bhandari.

A research design is a strategy for answering your   research question  using empirical data. Creating a research design means making decisions about:

  • Your overall research objectives and approach
  • Whether you’ll rely on primary research or secondary research
  • Your sampling methods or criteria for selecting subjects
  • Your data collection methods
  • The procedures you’ll follow to collect data
  • Your data analysis methods

A well-planned research design helps ensure that your methods match your research objectives and that you use the right kind of analysis for your data.

Table of contents

Step 1: consider your aims and approach, step 2: choose a type of research design, step 3: identify your population and sampling method, step 4: choose your data collection methods, step 5: plan your data collection procedures, step 6: decide on your data analysis strategies, other interesting articles, frequently asked questions about research design.

  • Introduction

Before you can start designing your research, you should already have a clear idea of the research question you want to investigate.

There are many different ways you could go about answering this question. Your research design choices should be driven by your aims and priorities—start by thinking carefully about what you want to achieve.

The first choice you need to make is whether you’ll take a qualitative or quantitative approach.

Qualitative research designs tend to be more flexible and inductive , allowing you to adjust your approach based on what you find throughout the research process.

Quantitative research designs tend to be more fixed and deductive , with variables and hypotheses clearly defined in advance of data collection.

It’s also possible to use a mixed-methods design that integrates aspects of both approaches. By combining qualitative and quantitative insights, you can gain a more complete picture of the problem you’re studying and strengthen the credibility of your conclusions.

Practical and ethical considerations when designing research

As well as scientific considerations, you need to think practically when designing your research. If your research involves people or animals, you also need to consider research ethics .

  • How much time do you have to collect data and write up the research?
  • Will you be able to gain access to the data you need (e.g., by travelling to a specific location or contacting specific people)?
  • Do you have the necessary research skills (e.g., statistical analysis or interview techniques)?
  • Will you need ethical approval ?

At each stage of the research design process, make sure that your choices are practically feasible.

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Within both qualitative and quantitative approaches, there are several types of research design to choose from. Each type provides a framework for the overall shape of your research.

Types of quantitative research designs

Quantitative designs can be split into four main types.

  • Experimental and   quasi-experimental designs allow you to test cause-and-effect relationships
  • Descriptive and correlational designs allow you to measure variables and describe relationships between them.

With descriptive and correlational designs, you can get a clear picture of characteristics, trends and relationships as they exist in the real world. However, you can’t draw conclusions about cause and effect (because correlation doesn’t imply causation ).

Experiments are the strongest way to test cause-and-effect relationships without the risk of other variables influencing the results. However, their controlled conditions may not always reflect how things work in the real world. They’re often also more difficult and expensive to implement.

Types of qualitative research designs

Qualitative designs are less strictly defined. This approach is about gaining a rich, detailed understanding of a specific context or phenomenon, and you can often be more creative and flexible in designing your research.

The table below shows some common types of qualitative design. They often have similar approaches in terms of data collection, but focus on different aspects when analyzing the data.

Your research design should clearly define who or what your research will focus on, and how you’ll go about choosing your participants or subjects.

In research, a population is the entire group that you want to draw conclusions about, while a sample is the smaller group of individuals you’ll actually collect data from.

Defining the population

A population can be made up of anything you want to study—plants, animals, organizations, texts, countries, etc. In the social sciences, it most often refers to a group of people.

For example, will you focus on people from a specific demographic, region or background? Are you interested in people with a certain job or medical condition, or users of a particular product?

The more precisely you define your population, the easier it will be to gather a representative sample.

  • Sampling methods

Even with a narrowly defined population, it’s rarely possible to collect data from every individual. Instead, you’ll collect data from a sample.

To select a sample, there are two main approaches: probability sampling and non-probability sampling . The sampling method you use affects how confidently you can generalize your results to the population as a whole.

Probability sampling is the most statistically valid option, but it’s often difficult to achieve unless you’re dealing with a very small and accessible population.

For practical reasons, many studies use non-probability sampling, but it’s important to be aware of the limitations and carefully consider potential biases. You should always make an effort to gather a sample that’s as representative as possible of the population.

Case selection in qualitative research

In some types of qualitative designs, sampling may not be relevant.

For example, in an ethnography or a case study , your aim is to deeply understand a specific context, not to generalize to a population. Instead of sampling, you may simply aim to collect as much data as possible about the context you are studying.

In these types of design, you still have to carefully consider your choice of case or community. You should have a clear rationale for why this particular case is suitable for answering your research question .

For example, you might choose a case study that reveals an unusual or neglected aspect of your research problem, or you might choose several very similar or very different cases in order to compare them.

Data collection methods are ways of directly measuring variables and gathering information. They allow you to gain first-hand knowledge and original insights into your research problem.

You can choose just one data collection method, or use several methods in the same study.

Survey methods

Surveys allow you to collect data about opinions, behaviors, experiences, and characteristics by asking people directly. There are two main survey methods to choose from: questionnaires and interviews .

Observation methods

Observational studies allow you to collect data unobtrusively, observing characteristics, behaviors or social interactions without relying on self-reporting.

Observations may be conducted in real time, taking notes as you observe, or you might make audiovisual recordings for later analysis. They can be qualitative or quantitative.

Other methods of data collection

There are many other ways you might collect data depending on your field and topic.

If you’re not sure which methods will work best for your research design, try reading some papers in your field to see what kinds of data collection methods they used.

Secondary data

If you don’t have the time or resources to collect data from the population you’re interested in, you can also choose to use secondary data that other researchers already collected—for example, datasets from government surveys or previous studies on your topic.

With this raw data, you can do your own analysis to answer new research questions that weren’t addressed by the original study.

Using secondary data can expand the scope of your research, as you may be able to access much larger and more varied samples than you could collect yourself.

However, it also means you don’t have any control over which variables to measure or how to measure them, so the conclusions you can draw may be limited.

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As well as deciding on your methods, you need to plan exactly how you’ll use these methods to collect data that’s consistent, accurate, and unbiased.

Planning systematic procedures is especially important in quantitative research, where you need to precisely define your variables and ensure your measurements are high in reliability and validity.

Operationalization

Some variables, like height or age, are easily measured. But often you’ll be dealing with more abstract concepts, like satisfaction, anxiety, or competence. Operationalization means turning these fuzzy ideas into measurable indicators.

If you’re using observations , which events or actions will you count?

If you’re using surveys , which questions will you ask and what range of responses will be offered?

You may also choose to use or adapt existing materials designed to measure the concept you’re interested in—for example, questionnaires or inventories whose reliability and validity has already been established.

Reliability and validity

Reliability means your results can be consistently reproduced, while validity means that you’re actually measuring the concept you’re interested in.

For valid and reliable results, your measurement materials should be thoroughly researched and carefully designed. Plan your procedures to make sure you carry out the same steps in the same way for each participant.

If you’re developing a new questionnaire or other instrument to measure a specific concept, running a pilot study allows you to check its validity and reliability in advance.

Sampling procedures

As well as choosing an appropriate sampling method , you need a concrete plan for how you’ll actually contact and recruit your selected sample.

That means making decisions about things like:

  • How many participants do you need for an adequate sample size?
  • What inclusion and exclusion criteria will you use to identify eligible participants?
  • How will you contact your sample—by mail, online, by phone, or in person?

If you’re using a probability sampling method , it’s important that everyone who is randomly selected actually participates in the study. How will you ensure a high response rate?

If you’re using a non-probability method , how will you avoid research bias and ensure a representative sample?

Data management

It’s also important to create a data management plan for organizing and storing your data.

Will you need to transcribe interviews or perform data entry for observations? You should anonymize and safeguard any sensitive data, and make sure it’s backed up regularly.

Keeping your data well-organized will save time when it comes to analyzing it. It can also help other researchers validate and add to your findings (high replicability ).

On its own, raw data can’t answer your research question. The last step of designing your research is planning how you’ll analyze the data.

Quantitative data analysis

In quantitative research, you’ll most likely use some form of statistical analysis . With statistics, you can summarize your sample data, make estimates, and test hypotheses.

Using descriptive statistics , you can summarize your sample data in terms of:

  • The distribution of the data (e.g., the frequency of each score on a test)
  • The central tendency of the data (e.g., the mean to describe the average score)
  • The variability of the data (e.g., the standard deviation to describe how spread out the scores are)

The specific calculations you can do depend on the level of measurement of your variables.

Using inferential statistics , you can:

  • Make estimates about the population based on your sample data.
  • Test hypotheses about a relationship between variables.

Regression and correlation tests look for associations between two or more variables, while comparison tests (such as t tests and ANOVAs ) look for differences in the outcomes of different groups.

Your choice of statistical test depends on various aspects of your research design, including the types of variables you’re dealing with and the distribution of your data.

Qualitative data analysis

In qualitative research, your data will usually be very dense with information and ideas. Instead of summing it up in numbers, you’ll need to comb through the data in detail, interpret its meanings, identify patterns, and extract the parts that are most relevant to your research question.

Two of the most common approaches to doing this are thematic analysis and discourse analysis .

There are many other ways of analyzing qualitative data depending on the aims of your research. To get a sense of potential approaches, try reading some qualitative research papers in your field.

If you want to know more about the research process , methodology , research bias , or statistics , make sure to check out some of our other articles with explanations and examples.

  • Simple random sampling
  • Stratified sampling
  • Cluster sampling
  • Likert scales
  • Reproducibility

 Statistics

  • Null hypothesis
  • Statistical power
  • Probability distribution
  • Effect size
  • Poisson distribution

Research bias

  • Optimism bias
  • Cognitive bias
  • Implicit bias
  • Hawthorne effect
  • Anchoring bias
  • Explicit bias

A research design is a strategy for answering your   research question . It defines your overall approach and determines how you will collect and analyze data.

A well-planned research design helps ensure that your methods match your research aims, that you collect high-quality data, and that you use the right kind of analysis to answer your questions, utilizing credible sources . This allows you to draw valid , trustworthy conclusions.

Quantitative research designs can be divided into two main categories:

  • Correlational and descriptive designs are used to investigate characteristics, averages, trends, and associations between variables.
  • Experimental and quasi-experimental designs are used to test causal relationships .

Qualitative research designs tend to be more flexible. Common types of qualitative design include case study , ethnography , and grounded theory designs.

The priorities of a research design can vary depending on the field, but you usually have to specify:

  • Your research questions and/or hypotheses
  • Your overall approach (e.g., qualitative or quantitative )
  • The type of design you’re using (e.g., a survey , experiment , or case study )
  • Your data collection methods (e.g., questionnaires , observations)
  • Your data collection procedures (e.g., operationalization , timing and data management)
  • Your data analysis methods (e.g., statistical tests  or thematic analysis )

A sample is a subset of individuals from a larger population . Sampling means selecting the group that you will actually collect data from in your research. For example, if you are researching the opinions of students in your university, you could survey a sample of 100 students.

In statistics, sampling allows you to test a hypothesis about the characteristics of a population.

Operationalization means turning abstract conceptual ideas into measurable observations.

For example, the concept of social anxiety isn’t directly observable, but it can be operationally defined in terms of self-rating scores, behavioral avoidance of crowded places, or physical anxiety symptoms in social situations.

Before collecting data , it’s important to consider how you will operationalize the variables that you want to measure.

A research project is an academic, scientific, or professional undertaking to answer a research question . Research projects can take many forms, such as qualitative or quantitative , descriptive , longitudinal , experimental , or correlational . What kind of research approach you choose will depend on your topic.

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Study documents safety, improvements from stem cell therapy after spinal cord injury

Susan Barber Lindquist

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ROCHESTER, Minn. — A Mayo Clinic study shows stem cells derived from patients' own fat are safe and may improve sensation and movement after traumatic spinal cord injuries . The findings from the phase 1 clinical trial appear in Nature Communications . The results of this early research offer insights on the potential of cell therapy for people living with spinal cord injuries and paralysis for whom options to improve function are extremely limited.

In the study of 10 adults, the research team noted seven participants demonstrated improvements based on the American Spinal Injury Association (ASIA) Impairment Scale. Improvements included increased sensation when tested with pinprick and light touch, increased strength in muscle motor groups, and recovery of voluntary anal contraction, which aids in bowel function. The scale has five levels, ranging from complete loss of function to normal function. The seven participants who improved each moved up at least one level on the ASIA scale. Three patients in the study had no response, meaning they did not improve but did not get worse.

"This study documents the safety and potential benefit of stem cells and regenerative medicine," says Mohamad Bydon, M.D. , a Mayo Clinic neurosurgeon and first author of the study. "Spinal cord injury is a complex condition. Future research may show whether stem cells in combination with other therapies could be part of a new paradigm of treatment to improve outcomes for patients."

No serious adverse events were reported after stem cell treatment. The most commonly reported side effects were headache and musculoskeletal pain that resolved with over-the-counter treatment.

In addition to evaluating safety, this phase 1 clinical trial had a secondary outcome of assessing changes in motor and sensory function. The authors note that motor and sensory results are to be interpreted with caution given limits of phase 1 trials. Additional research is underway among a larger group of participants to further assess risks and benefits.

The full data on the 10 patients follows a 2019 case report that highlighted the experience of the first study participant who demonstrated significant improvement in motor and sensory function.

Watch: Dr. Mohamad Bydon discusses improvements in research study

Journalists: Broadcast-quality sound bites are available in the downloads at the end of the post. Please courtesy: "Mayo Clinic News Network." Name super/CG: Mohamad Bydon, M.D./Neurosurgery/Mayo Clinic.

Stem cells' mechanism of action not fully understood

In the multidisciplinary clinical trial, participants had spinal cord injuries from motor vehicle accidents, falls and other causes. Six had neck injuries; four had back injuries. Participants ranged in age from 18 to 65.

Participants' stem cells were collected by taking a small amount of fat from a 1- to 2-inch incision in the abdomen or thigh. Over four weeks, the cells were expanded in the laboratory to 100 million cells and then injected into the patients' lumbar spine in the lower back. Over two years, each study participant was evaluated at Mayo Clinic 10 times.

Although it is understood that stem cells move toward areas of inflammation — in this case the location of the spinal cord injury — the cells' mechanism of interacting with the spinal cord is not fully understood, Dr. Bydon says. As part of the study, researchers analyzed changes in participants' MRIs and cerebrospinal fluid as well as in responses to pain, pressure and other sensation. The investigators are looking for clues to identify injury processes at a cellular level and avenues for potential regeneration and healing.

scientific research on study

The spinal cord has limited ability to repair its cells or make new ones. Patients typically experience most of their recovery in the first six to 12 months after injuries occur. Improvement generally stops 12 to 24 months after injury. In the study, one patient with a cervical spine injury of the neck received stem cells 22 months after injury and improved one level on the ASIA scale after treatment.

Two of three patients with complete injuries of the thoracic spine — meaning they had no feeling or movement below their injury between the base of the neck and mid-back — moved up two ASIA levels after treatment. Each regained some sensation and some control of movement below the level of injury. Based on researchers' understanding of traumatic thoracic spinal cord injury, only 5% of people with a complete injury would be expected to regain any feeling or movement.

"In spinal cord injury, even a mild improvement can make a significant difference in that patient's quality of life," Dr. Bydon says.

Research continues into stem cells for spinal cord injuries

Stem cells are used mainly in research in the U.S., and fat-derived stem cell treatment for spinal cord injury is considered experimental by the Food and Drug Administration.

Between 250,000 and 500,000 people worldwide suffer a spinal cord injury each year, according to the  World Health Organization .

An important next step is assessing the effectiveness of stem cell therapies and subsets of patients who would most benefit, Dr. Bydon says. Research is continuing with a larger, controlled trial that randomly assigns patients to receive either the stem cell treatment or a placebo without stem cells.

"For years, treatment of spinal cord injury has been limited to supportive care, more specifically stabilization surgery and physical therapy," Dr. Bydon says. "Many historical textbooks state that this condition does not improve. In recent years, we have seen findings from the medical and scientific community that challenge prior assumptions. This research is a step forward toward the ultimate goal of improving treatments for patients."

Dr. Bydon is the Charles B. and Ann L. Johnson Professor of Neurosurgery. This research was made possible with support from Leonard A. Lauder, C and A Johnson Family Foundation, The Park Foundation, Sanger Family Foundation, Eileen R.B. and Steve D. Scheel, Schultz Family Foundation, and other generous Mayo Clinic benefactors. The research is funded in part by a Mayo Clinic Transform the Practice grant.

Review the study for a complete list of authors and funding.

About Mayo Clinic Mayo Clinic is a nonprofit organization committed to innovation in clinical practice, education and research, and providing compassion, expertise and answers to everyone who needs healing. Visit the  Mayo Clinic News Network  for additional Mayo Clinic news.

Media contact:

  • Susan Barber Lindquist, Mayo Clinic Communications, [email protected]
  • Personal journey shapes unique perspective Mayo Clinic scientists pioneer immunotherapy technique for autoimmune diseases

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Humans can increase biodiversity, archaeological study shows

Cultural diversity is likely to have an overall positive effect on the biodiversity of ecosystems. The homogenization of human life forms may therefore be regarded as an important motor of the ongoing major extinction events in the 'Age of Humans' (Anthropocene). Dr Shumon T. Hussain from the University of Cologne and Dr Chris Baumann from the University of Tübingen come to this conclusion in their recent article 'The human side of biodiversity: coevolution of the human niche, paleo-synanthropy and ecosystem complexity in the deep human past' published in the journal Philosophical Transactions of the Royal Society B.

The article fits into the current thematic focus 'Multispecies Conviviality' of the University of Cologne's Research Hub MESH (Multidisciplinary Environmental Studies in the Humanities).

In their publication, the scientists examine the role of past humans in the evolution and control of biodiversity on our planet. The archaeologists offer a deep-time perspective grounded in material and ecological data to argue that the idea that humans had lived harmoniously with nature as hunter-gatherers mischaracterizes the fundamental problem of human interaction with ecosystems. The scientists also criticize that in the recent past, with regard to the aforementioned extinction events, the so-called biodiversity loss in the Anthropocene, attempts have often been made to highlight that people had actively intervened in their ecosystem more than 10,000 years ago, notably with negative consequences.

The researchers suggest that the relationship between humans and ecosystems has always been much more complicated and complex, and that, in addition to negative effects, there are also positive effects on biodiversity that follow certain rules. "Oftentimes, it can even be said that biodiversity loss occurs locally due to human activity, but biodiversity is strongly promoted elsewhere; these dynamics must therefore be placed in a wider context," said Hussain.

The research combines various case studies from the Late Pleistocene (approx. 120,000 to 11,800 years before present) and is also based on a recent study of the two authors on ravens from the ice age, which shows that these birds benefited from humans as neighbours about 30,000 years ago -- especially from food options that hunter-gatherers in the environment provided for these animals.

The archaeologists based their research on the results of zooarchaeological and stable isotope analyses, which were applied in the case of ravens, and used this and other already published, contextual archaeological information to show that such processes can lead to an increase in biodiversity on a local level. This is because certain animals benefit from human influence and others that are excluded locally by humans, such as larger predators, move to other areas. Overall, this increases the heterogeneity and complexity of such ecosystems, thereby often resulting in a positive effect on overall biodiversity.

"Ultimately, we try to argue that biodiversity regimes cannot be separated from human influence and that not all of these influences are merely negative," explained Shumon Hussain. "It also follows that increased diversity in human life forms probably has an overall positive effect on biodiversity as a whole, and that a decisive driver of the biodiversity crisis in the Anthropocene is in part also the homogenization of human life in nature and with it."

  • Ecology Research
  • Biodiversity
  • Early Humans
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  • Southeast Asia coral reefs
  • Marine conservation
  • Biodiversity Action Plan

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Journal Reference :

  • Shumon T. Hussain, Chris Baumann. The human side of biodiversity: coevolution of the human niche, palaeo-synanthropy and ecosystem complexity in the deep human past . Philosophical Transactions of the Royal Society B: Biological Sciences , 2024; 379 (1902) DOI: 10.1098/rstb.2023.0021

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December 21, 2015

The Most Popular Science Studies of the Year

The attention-grabbing academic papers of 2015 include research on sexist video games and Homo erectus

By Jennifer Hackett

scientific research on study

Issouf Sanogo Getty Images

The 2015 science research that set the Internet abuzz included a super antibiotic, plastics pollution in the ocean , climate change , and species extinction , according to Altmetric , a start-up that analyzes online activity surrounding academic papers.

Research never rests: every year thousands of scientific articles are published across dozens of journals and disciplines. Some studies capture the media’s attention and get coverage in numerous news stories; others speak to a more niche audience and take off in passionate social media discussions. For the second year Altmetric has compiled a list of the top 100 academic articles of the year . They studied the attention garnered by scientific articles from November 2014 up until November 16, 2015, examining how papers fared in news coverage and social media outlets such as Twitter, Facebook, and the popular Chinese microblogging site Sina Weibo. They also looked to see if studies were referenced by Wikipedia and policy papers outlining plans of actions written by analysts and think tanks.

To be clear, theirs is not a list of the most important studies of 2015. “It’s not about quality, necessarily, or even always about impact,” says Stacy Konkiel, an outreach manager at Altmetric. “We’re just looking at attention.” That explains how the twentieth overall story achieved its rank. On the surface, it was a paleontology paper. But it wasn’t the new horned dinosaur that interested the public: It was a marriage proposal tucked away in the paper’s footnotes.

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This year’s list includes studies from 34 different journals—both traditional and open access, the latter of which is steadily gaining ground and tends to get more of a boost from social media. Forty-two of the top 100 studies came from an open access journal.

More than half of the hottest studies were health-related, with environment-related studies trending right behind. Some of these studies might have gotten a boost from the attention on climate change due to the COP21 talks in Paris. These papers were particularly successful with traditional news coverage, with some having more than 100 news articles written about them.

Health and environment are typically hot topics, but there were surprises too: On the list was a story that gained quite a bit of traction (the eighth most popular article ) despite the fact it didn’t belong to either of the popular categories and only had two news articles written about it. The study, which compared the time effectiveness of major document preparation systems (word processors, such as Microsoft Word and the science-beloved LaTeX,) used by researchers to create their manuscripts saw 1,000 more tweets than any of the other top ten articles. “That is very surprising to me, personally, because it’s such a niche audience,” Konkiel says. “It obviously captured the interest of scientists who are very active on social media.”

The most-tweeted about article, a psychology study investigating whether or not sexist video games imparted sexist attitudes or mindsets onto the people who played them, was also an outlier. The study shared the most via Facebook, on the other hand, was about Homo erectus using shells as tools. Neither, clearly, involved health or environment. “We’re definitely seeing social media amplify studies that the mainstream media wouldn’t pick up,” Konkiel says. “As long as there’s an active community on social media, we see stories that otherwise might be niche get a lot of attention as measured by our score.”

“It’s not just about how many citations you’ve got or the impact factor of the journal you’ve published in, it’s who’s they’re sharing it with, and if they’re incorporating it into their day to day lives,” Konkiel says.

A Solar Eclipse Means Big Science

By Katrina Miller April 1, 2024

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Katrina Miller

On April 8, cameras all over North America will make a “megamovie” of the sun’s corona, like this one from the 2017 eclipse. The time lapse will help scientists track the behavior of jets and plumes on the sun’s surface.

There’s more science happening along the path of totality →

An app named SunSketcher will help the public take pictures of the eclipse with their phones.

Scientists will use these images to study deviations in the shape of the solar surface , which will help them understand the sun’s churning behavior below.

The sun right now is approaching peak activity. More than 40 telescope stations along the eclipse’s path will record totality.

By comparing these videos to what was captured in 2017 — when the sun was at a lull — researchers can learn how the sun’s magnetism drives the solar wind, or particles that stream through the solar system.

Students will launch giant balloons equipped with cameras and sensors along the eclipse’s path.

Their measurements may improve weather forecasting , and also produce a bird’s eye view of the moon’s shadow moving across the Earth.

Ham radio operators will send signals to each other across the path of totality to study how the density of electrons in Earth’s upper atmosphere changes .

This can help quantify how space weather produced by the sun disrupts radar communication systems.

(Animation by Dr. Joseph Huba, Syntek Technologies; HamSCI Project, Dr. Nathaniel Frissell, the University of Scranton, NSF and NASA.)

NASA is also studying Earth’s atmosphere, but far from the path of totality.

In Virginia, the agency will launch rockets during the eclipse to measure how local drops in sunlight cause ripple effects hundreds of miles away . The data will clarify how eclipses and other solar events affect satellite communications, including GPS.

Biologists in San Antonio plan to stash recording devices in beehives to study how bees orient themselves using sunlight , and how the insects respond to the sudden atmospheric changes during a total eclipse.

Two researchers in southern Illinois will analyze social media posts to understand tourism patterns in remote towns , including when visitors arrive, where they come from and what they do during their visits.

Results can help bolster infrastructure to support large events in rural areas.

Read more about the eclipse:

The sun flares at the edge of the moon during a total eclipse.

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Scientific Method Steps in Psychology Research

Steps, Uses, and Key Terms

Kendra Cherry, MS, is a psychosocial rehabilitation specialist, psychology educator, and author of the "Everything Psychology Book."

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Emily is a board-certified science editor who has worked with top digital publishing brands like Voices for Biodiversity, Study.com, GoodTherapy, Vox, and Verywell.

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Verywell / Theresa Chiechi

How do researchers investigate psychological phenomena? They utilize a process known as the scientific method to study different aspects of how people think and behave.

When conducting research, the scientific method steps to follow are:

  • Observe what you want to investigate
  • Ask a research question and make predictions
  • Test the hypothesis and collect data
  • Examine the results and draw conclusions
  • Report and share the results 

This process not only allows scientists to investigate and understand different psychological phenomena but also provides researchers and others a way to share and discuss the results of their studies.

Generally, there are five main steps in the scientific method, although some may break down this process into six or seven steps. An additional step in the process can also include developing new research questions based on your findings.

What Is the Scientific Method?

What is the scientific method and how is it used in psychology?

The scientific method consists of five steps. It is essentially a step-by-step process that researchers can follow to determine if there is some type of relationship between two or more variables.

By knowing the steps of the scientific method, you can better understand the process researchers go through to arrive at conclusions about human behavior.

Scientific Method Steps

While research studies can vary, these are the basic steps that psychologists and scientists use when investigating human behavior.

The following are the scientific method steps:

Step 1. Make an Observation

Before a researcher can begin, they must choose a topic to study. Once an area of interest has been chosen, the researchers must then conduct a thorough review of the existing literature on the subject. This review will provide valuable information about what has already been learned about the topic and what questions remain to be answered.

A literature review might involve looking at a considerable amount of written material from both books and academic journals dating back decades.

The relevant information collected by the researcher will be presented in the introduction section of the final published study results. This background material will also help the researcher with the first major step in conducting a psychology study: formulating a hypothesis.

Step 2. Ask a Question

Once a researcher has observed something and gained some background information on the topic, the next step is to ask a question. The researcher will form a hypothesis, which is an educated guess about the relationship between two or more variables

For example, a researcher might ask a question about the relationship between sleep and academic performance: Do students who get more sleep perform better on tests at school?

In order to formulate a good hypothesis, it is important to think about different questions you might have about a particular topic.

You should also consider how you could investigate the causes. Falsifiability is an important part of any valid hypothesis. In other words, if a hypothesis was false, there needs to be a way for scientists to demonstrate that it is false.

Step 3. Test Your Hypothesis and Collect Data

Once you have a solid hypothesis, the next step of the scientific method is to put this hunch to the test by collecting data. The exact methods used to investigate a hypothesis depend on exactly what is being studied. There are two basic forms of research that a psychologist might utilize: descriptive research or experimental research.

Descriptive research is typically used when it would be difficult or even impossible to manipulate the variables in question. Examples of descriptive research include case studies, naturalistic observation , and correlation studies. Phone surveys that are often used by marketers are one example of descriptive research.

Correlational studies are quite common in psychology research. While they do not allow researchers to determine cause-and-effect, they do make it possible to spot relationships between different variables and to measure the strength of those relationships. 

Experimental research is used to explore cause-and-effect relationships between two or more variables. This type of research involves systematically manipulating an independent variable and then measuring the effect that it has on a defined dependent variable .

One of the major advantages of this method is that it allows researchers to actually determine if changes in one variable actually cause changes in another.

While psychology experiments are often quite complex, a simple experiment is fairly basic but does allow researchers to determine cause-and-effect relationships between variables. Most simple experiments use a control group (those who do not receive the treatment) and an experimental group (those who do receive the treatment).

Step 4. Examine the Results and Draw Conclusions

Once a researcher has designed the study and collected the data, it is time to examine this information and draw conclusions about what has been found.  Using statistics , researchers can summarize the data, analyze the results, and draw conclusions based on this evidence.

So how does a researcher decide what the results of a study mean? Not only can statistical analysis support (or refute) the researcher’s hypothesis; it can also be used to determine if the findings are statistically significant.

When results are said to be statistically significant, it means that it is unlikely that these results are due to chance.

Based on these observations, researchers must then determine what the results mean. In some cases, an experiment will support a hypothesis, but in other cases, it will fail to support the hypothesis.

So what happens if the results of a psychology experiment do not support the researcher's hypothesis? Does this mean that the study was worthless?

Just because the findings fail to support the hypothesis does not mean that the research is not useful or informative. In fact, such research plays an important role in helping scientists develop new questions and hypotheses to explore in the future.

After conclusions have been drawn, the next step is to share the results with the rest of the scientific community. This is an important part of the process because it contributes to the overall knowledge base and can help other scientists find new research avenues to explore.

Step 5. Report the Results

The final step in a psychology study is to report the findings. This is often done by writing up a description of the study and publishing the article in an academic or professional journal. The results of psychological studies can be seen in peer-reviewed journals such as  Psychological Bulletin , the  Journal of Social Psychology ,  Developmental Psychology , and many others.

The structure of a journal article follows a specified format that has been outlined by the  American Psychological Association (APA) . In these articles, researchers:

  • Provide a brief history and background on previous research
  • Present their hypothesis
  • Identify who participated in the study and how they were selected
  • Provide operational definitions for each variable
  • Describe the measures and procedures that were used to collect data
  • Explain how the information collected was analyzed
  • Discuss what the results mean

Why is such a detailed record of a psychological study so important? By clearly explaining the steps and procedures used throughout the study, other researchers can then replicate the results. The editorial process employed by academic and professional journals ensures that each article that is submitted undergoes a thorough peer review, which helps ensure that the study is scientifically sound.

Once published, the study becomes another piece of the existing puzzle of our knowledge base on that topic.

Before you begin exploring the scientific method steps, here's a review of some key terms and definitions that you should be familiar with:

  • Falsifiable : The variables can be measured so that if a hypothesis is false, it can be proven false
  • Hypothesis : An educated guess about the possible relationship between two or more variables
  • Variable : A factor or element that can change in observable and measurable ways
  • Operational definition : A full description of exactly how variables are defined, how they will be manipulated, and how they will be measured

Uses for the Scientific Method

The  goals of psychological studies  are to describe, explain, predict and perhaps influence mental processes or behaviors. In order to do this, psychologists utilize the scientific method to conduct psychological research. The scientific method is a set of principles and procedures that are used by researchers to develop questions, collect data, and reach conclusions.

Goals of Scientific Research in Psychology

Researchers seek not only to describe behaviors and explain why these behaviors occur; they also strive to create research that can be used to predict and even change human behavior.

Psychologists and other social scientists regularly propose explanations for human behavior. On a more informal level, people make judgments about the intentions, motivations , and actions of others on a daily basis.

While the everyday judgments we make about human behavior are subjective and anecdotal, researchers use the scientific method to study psychology in an objective and systematic way. The results of these studies are often reported in popular media, which leads many to wonder just how or why researchers arrived at the conclusions they did.

Examples of the Scientific Method

Now that you're familiar with the scientific method steps, it's useful to see how each step could work with a real-life example.

Say, for instance, that researchers set out to discover what the relationship is between psychotherapy and anxiety .

  • Step 1. Make an observation : The researchers choose to focus their study on adults ages 25 to 40 with generalized anxiety disorder.
  • Step 2. Ask a question : The question they want to answer in their study is: Do weekly psychotherapy sessions reduce symptoms in adults ages 25 to 40 with generalized anxiety disorder?
  • Step 3. Test your hypothesis : Researchers collect data on participants' anxiety symptoms . They work with therapists to create a consistent program that all participants undergo. Group 1 may attend therapy once per week, whereas group 2 does not attend therapy.
  • Step 4. Examine the results : Participants record their symptoms and any changes over a period of three months. After this period, people in group 1 report significant improvements in their anxiety symptoms, whereas those in group 2 report no significant changes.
  • Step 5. Report the results : Researchers write a report that includes their hypothesis, information on participants, variables, procedure, and conclusions drawn from the study. In this case, they say that "Weekly therapy sessions are shown to reduce anxiety symptoms in adults ages 25 to 40."

Of course, there are many details that go into planning and executing a study such as this. But this general outline gives you an idea of how an idea is formulated and tested, and how researchers arrive at results using the scientific method.

Erol A. How to conduct scientific research ? Noro Psikiyatr Ars . 2017;54(2):97-98. doi:10.5152/npa.2017.0120102

University of Minnesota. Psychologists use the scientific method to guide their research .

Shaughnessy, JJ, Zechmeister, EB, & Zechmeister, JS. Research Methods In Psychology . New York: McGraw Hill Education; 2015.

By Kendra Cherry, MSEd Kendra Cherry, MS, is a psychosocial rehabilitation specialist, psychology educator, and author of the "Everything Psychology Book."

Incorporate STEM journalism in your classroom

  • Exercise type: Activity
  • Topic: Science & Society
  • Category: Research & Design
  • Category: Diversity in STEM

How bias affects scientific research

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Purpose: Students will work in groups to evaluate bias in scientific research and engineering projects and to develop guidelines for minimizing potential biases.

Procedural overview: After reading the Science News for Students article “ Think you’re not biased? Think again ,” students will discuss types of bias in scientific research and how to identify it. Students will then search the Science News archive for examples of different types of bias in scientific and medical research. Students will read the National Institute of Health’s Policy on Sex as a Biological Variable and analyze how this policy works to reduce bias in scientific research on the basis of sex and gender. Based on their exploration of bias, students will discuss the benefits and limitations of research guidelines for minimizing particular types of bias and develop guidelines of their own.

Approximate class time: 2 class periods

How Bias Affects Scientific Research student guide

Computer with access to the Science News archive

Interactive meeting and screen-sharing application for virtual learning (optional)

Directions for teachers:

One of the guiding principles of scientific inquiry is objectivity. Objectivity is the idea that scientific questions, methods and results should not be affected by the personal values, interests or perspectives of researchers. However, science is a human endeavor, and experimental design and analysis of information are products of human thought processes. As a result, biases may be inadvertently introduced into scientific processes or conclusions.

In scientific circles, bias is described as any systematic deviation between the results of a study and the “truth.” Bias is sometimes described as a tendency to prefer one thing over another, or to favor one person, thing or explanation in a way that prevents objectivity or that influences the outcome of a study or the understanding of a phenomenon. Bias can be introduced in multiple points during scientific research — in the framing of the scientific question, in the experimental design, in the development or implementation of processes used to conduct the research, during collection or analysis of data, or during the reporting of conclusions.

Researchers generally recognize several different sources of bias, each of which can strongly affect the results of STEM research. Three types of bias that often occur in scientific and medical studies are researcher bias, selection bias and information bias.

Researcher bias occurs when the researcher conducting the study is in favor of a certain result. Researchers can influence outcomes through their study design choices, including who they choose to include in a study and how data are interpreted. Selection bias can be described as an experimental error that occurs when the subjects of the study do not accurately reflect the population to whom the results of the study will be applied. This commonly happens as unequal inclusion of subjects of different races, sexes or genders, ages or abilities. Information bias occurs as a result of systematic errors during the collection, recording or analysis of data.

When bias occurs, a study’s results may not accurately represent phenomena in the real world, or the results may not apply in all situations or equally for all populations. For example, if a research study does not address the full diversity of people to whom the solution will be applied, then the researchers may have missed vital information about whether and how that solution will work for a large percentage of a target population.

Bias can also affect the development of engineering solutions. For example, a new technology product tested only with teenagers or young adults who are comfortable using new technologies may have user experience issues when placed in the hands of older adults or young children.

Want to make it a virtual lesson? Post the links to the  Science News for Students article “ Think you’re not biased? Think again ,” and the National Institutes of Health information on sickle-cell disease . A link to additional resources can be provided for the students who want to know more. After students have reviewed the information at home, discuss the four questions in the setup and the sickle-cell research scenario as a class. When the students have a general understanding of bias in research, assign students to breakout rooms to look for examples of different types of bias in scientific and medical research, to discuss the Science News article “ Biomedical studies are including more female subjects (finally) ” and the National Institute of Health’s Policy on Sex as a Biological Variable and to develop bias guidelines of their own. Make sure the students have links to all articles they will need to complete their work. Bring the groups back together for an all-class discussion of the bias guidelines they write.

Assign the Science News for Students article “ Think you’re not biased? Think again ” as homework reading to introduce students to the core concepts of scientific objectivity and bias. Request that they answer the first two questions on their guide before the first class discussion on this topic. In this discussion, you will cover the idea of objective truth and introduce students to the terminology used to describe bias. Use the background information to decide what level of detail you want to give to your students.

As students discuss bias, help them understand objective and subjective data and discuss the importance of gathering both kinds of data. Explain to them how these data differ. Some phenomena — for example, body temperature, blood type and heart rate — can be objectively measured. These data tend to be quantitative. Other phenomena cannot be measured objectively and must be considered subjectively. Subjective data are based on perceptions, feelings or observations and tend to be qualitative rather than quantitative. Subjective measurements are common and essential in biomedical research, as they can help researchers understand whether a therapy changes a patient’s experience. For instance, subjective data about the amount of pain a patient feels before and after taking a medication can help scientists understand whether and how the drug works to alleviate pain. Subjective data can still be collected and analyzed in ways that attempt to minimize bias.

Try to guide student discussion to include a larger context for bias by discussing the effects of bias on understanding of an “objective truth.” How can someone’s personal views and values affect how they analyze information or interpret a situation?

To help students understand potential effects of biases, present them with the following scenario based on information from the National Institutes of Health :

Sickle-cell disease is a group of inherited disorders that cause abnormalities in red blood cells. Most of the people who have sickle-cell disease are of African descent; it also appears in populations from the Mediterranean, India and parts of Latin America. Males and females are equally likely to inherit the condition. Imagine that a therapy was developed to treat the condition, and clinical trials enlisted only male subjects of African descent. How accurately would the results of that study reflect the therapy’s effectiveness for all people who suffer from sickle-cell disease?

In the sickle-cell scenario described above, scientists will have a good idea of how the therapy works for males of African descent. But they may not be able to accurately predict how the therapy will affect female patients or patients of different races or ethnicities. Ask the students to consider how they would devise a study that addressed all the populations affected by this disease.

Before students move on, have them answer the following questions. The first two should be answered for homework and discussed in class along with the remaining questions.

1.What is bias?

In common terms, bias is a preference for or against one idea, thing or person. In scientific research, bias is a systematic deviation between observations or interpretations of data and an accurate description of a phenomenon.

2. How can biases affect the accuracy of scientific understanding of a phenomenon? How can biases affect how those results are applied?

Bias can cause the results of a scientific study to be disproportionately weighted in favor of one result or group of subjects. This can cause misunderstandings of natural processes that may make conclusions drawn from the data unreliable. Biased procedures, data collection or data interpretation can affect the conclusions scientists draw from a study and the application of those results. For example, if the subjects that participate in a study testing an engineering design do not reflect the diversity of a population, the end product may not work as well as desired for all users.

3. Describe two potential sources of bias in a scientific, medical or engineering research project. Try to give specific examples.

Researchers can intentionally or unintentionally introduce biases as a result of their attitudes toward the study or its purpose or toward the subjects or a group of subjects. Bias can also be introduced by methods of measuring, collecting or reporting data. Examples of potential sources of bias include testing a small sample of subjects, testing a group of subjects that is not diverse and looking for patterns in data to confirm ideas or opinions already held.

4. How can potential biases be identified and eliminated before, during or after a scientific study?

Students should brainstorm ways to identify sources of bias in the design of research studies. They may suggest conducting implicit bias testing or interviews before a study can be started, developing guidelines for research projects, peer review of procedures and samples/subjects before beginning a study, and peer review of data and conclusions after the study is completed and before it is published. Students may focus on the ideals of transparency and replicability of results to help reduce biases in scientific research.

Obtain and evaluate information about bias

Students will now work in small groups to select and analyze articles for different types of bias in scientific and medical research. Students will start by searching the Science News or Science News for Students archives and selecting articles that describe scientific studies or engineering design projects. If the Science News or Science News for Students articles chosen by students do not specifically cite and describe a study, students should consult the Citations at the end of the article for links to related primary research papers. Students may need to read the methods section and the conclusions of the primary research paper to better understand the project’s design and to identify potential biases. Do not assume that every scientific paper features biased research.

Student groups should evaluate the study or engineering design project outlined in the article to identify any biases in the experimental design, data collection, analysis or results. Students may need additional guidance for identifying biases. Remind them of the prior discussion about sources of bias and task them to review information about indicators of bias. Possible indicators include extreme language such as all , none or nothing ; emotional appeals rather than logical arguments; proportions of study subjects with specific characteristics such as gender, race or age; arguments that support or refute one position over another and oversimplifications or overgeneralizations. Students may also want to look for clues related to the researchers’ personal identity such as race, religion or gender. Information on political or religious points of view, sources of funding or professional affiliations may also suggest biases.

Students should also identify any deliberate attempts to reduce or eliminate bias in the project or its results. Then groups should come back together and share the results of their analysis with the class.

If students need support in searching the archives for appropriate articles, encourage groups to brainstorm search terms that may turn up related articles. Some potential search terms include bias , study , studies , experiment , engineer , new device , design , gender , sex , race , age , aging , young , old , weight , patients , survival or medical .

If you are short on time or students do not have access to the Science News or Science News for Students archive, you may want to provide articles for students to review. Some suggested articles are listed in the additional resources  below.

Once groups have selected their articles, students should answer the following questions in their groups.

1. Record the title and URL of the article and write a brief summary of the study or project.

Answers will vary, but students should accurately cite the article evaluated and summarize the study or project described in the article. Sample answer: We reviewed the Science News article “Even brain images can be biased,” which can be found at www.sciencenews.org/blog/scicurious/even-brain-images-can-be-biased. This article describes how scientific studies of human brains that involve electronic images of brains tend to include study subjects from wealthier and more highly educated households and how researchers set out to collect new data to make the database of brain images more diverse.

2. What sources of potential bias (if any) did you identify in the study or project? Describe any procedures or policies deliberately included in the study or project to eliminate biases.

The article “Even brain images can be biased” describes how scientists identified a sampling bias in studies of brain images that resulted from the way subjects were recruited. Most of these studies were conducted at universities, so many college students volunteer to participate, which resulted in the samples being skewed toward wealthier, educated, white subjects. Scientists identified a database of pediatric brain images and evaluated the diversity of the subjects in that database. They found that although the subjects in that database were more ethnically diverse than the U.S. population, the subjects were generally from wealthier households and the parents of the subjects tended to be more highly educated than average. Scientists applied statistical methods to weight the data so that study samples from the database would more accurately reflect American demographics.

3. How could any potential biases in the study or design project have affected the results or application of the results to the target population?

Scientists studying the rate of brain development in children were able to recognize the sampling bias in the brain image database. When scientists were able to apply statistical methods to ensure a better representation of socioeconomically diverse samples, they saw a different pattern in the rate of brain development in children. Scientists learned that, in general, children’s brains matured more quickly than they had previously thought. They were able to draw new conclusions about how certain factors, such as family wealth and education, affected the rate at which children’s brains developed. But the scientsits also suggested that they needed to perform additional studies with a deliberately selected group of children to ensure true diversity in the samples.

In this phase, students will review the Science News article “ Biomedical studies are including more female subjects (finally) ” and the NIH Policy on Sex as a Biological Variable , including the “ guidance document .” Students will identify how sex and gender biases may have affected the results of biomedical research before NIH instituted its policy. The students will then work with their group to recommend other policies to minimize biases in biomedical research.

To guide their development of proposed guidelines, students should answer the following questions in their groups.

1. How have sex and gender biases affected the value and application of biomedical research?

Gender and sex biases in biomedical research have diminished the accuracy and quality of research studies and reduced the applicability of results to the entire population. When girls and women are not included in research studies, the responses and therapeutic outcomes of approximately half of the target population for potential therapies remain unknown.

2. Why do you think the NIH created its policy to reduce sex and gender biases?

In the guidance document, the NIH states that “There is a growing recognition that the quality and generalizability of biomedical research depends on the consideration of key biological variables, such as sex.” The document goes on to state that many diseases and conditions affect people of both sexes, and restricting diversity of biological variables, notably sex and gender, undermines the “rigor, transparency, and generalizability of research findings.”

3. What impact has the NIH Policy on Sex as a Biological Variable had on biomedical research?

The NIH’s policy that sex is factored into research designs, analyses and reporting tries to ensure that when developing and funding biomedical research studies, researchers and institutes address potential biases in the planning stages, which helps to reduce or eliminate those biases in the final study. Including females in biomedical research studies helps to ensure that the results of biomedical research are applicable to a larger proportion of the population, expands the therapies available to girls and women and improves their health care outcomes.

4. What other policies do you think the NIH could institute to reduce biases in biomedical research? If you were to recommend one set of additional guidelines for reducing bias in biomedical research, what guidelines would you propose? Why?

Students could suggest that the NIH should have similar policies related to race, gender identity, wealth/economic status and age. Students should identify a category of bias or an underserved segment of the population that they think needs to be addressed in order to improve biomedical research and health outcomes for all people and should recommend guidelines to reduce bias related to that group. Students recommending guidelines related to race might suggest that some populations, such as African Americans, are historically underserved in terms of access to medical services and health care, and they might suggest guidelines to help reduce the disparity. Students might recommend that a certain percentage of each biomedical research project’s sample include patients of diverse racial and ethnic backgrounds.

5. What biases would your suggested policy help eliminate? How would it accomplish that goal?

Students should describe how their proposed policy would address a discrepancy in the application of biomedical research to the entire human population. Race can be considered a biological variable, like sex, and race has been connected to higher or lower incidence of certain characteristics or medical conditions, such as blood types or diabetes, which sometimes affect how the body reponds to infectious agents, drugs, procedures or other therapies. By ensuring that people from diverse racial and ethnic groups are included in biomedical research studies, scientists and medical professionals can provide better medical care to members of those populations.

Class discussion about bias guidelines

Allow each group time to present its proposed bias-reducing guideline to another group and to receive feedback. Then provide groups with time to revise their guidelines, if necessary. Act as a facilitator while students conduct the class discussion. Use this time to assess individual and group progress. Students should demonstrate an understanding of different biases that may affect patient outcomes in biomedical research studies and in practical medical settings. As part of the group discussion, have students answer the following questions.

1. Why is it important to identify and eliminate biases in research and engineering design?

The goal of most scientific research and engineering projects is to improve the quality of life and the depth of understanding of the world we live in. By eliminating biases, we can better serve the entirety of the human population and the planet .

2. Were there any guidelines that were suggested by multiple groups? How do those actions or policies help reduce bias?

Answers will depend on the guidelines developed and recommended by other groups. Groups could suggest policies related to race, gender identity, wealth/economic status and age. Each group should clearly identify how its guidelines are designed to reduce bias and improve the quality of human life.

3. Which guidelines developed by your classmates do you think would most reduce the effects of bias on research results or engineering designs? Support your selection with evidence and scientific reasoning.

Answers will depend on the guidelines developed and recommended by other groups. Students should agree that guidelines that minimize inequities and improve health care outcomes for a larger group are preferred. Guidelines addressing inequities of race and wealth/economic status are likely to expand access to improved medical care for the largest percentage of the population. People who grow up in less economically advantaged settings have specific health issues related to nutrition and their access to clean water, for instance. Ensuring that people from the lowest economic brackets are represented in biomedical research improves their access to medical care and can dramatically change the length and quality of their lives.

Possible extension

Challenge students to honestly evaluate any biases they may have. Encourage them to take an Implicit Association Test (IAT) to identify any implicit biases they may not recognize. Harvard University has an online IAT platform where students can participate in different assessments to identify preferences and biases related to sex and gender, race, religion, age, weight and other factors. You may want to challenge students to take a test before they begin the activity, and then assign students to take a test after completing the activity to see if their preferences have changed. Students can report their results to the class if they want to discuss how awareness affects the expression of bias.

Additional resources

If you want additional resources for the discussion or to provide resources for student groups, check out the links below.

Additional Science News articles:

Even brain images can be biased

Data-driven crime prediction fails to erase human bias

What we can learn from how a doctor’s race can affect Black newborns’ survival

Bias in a common health care algorithm disproportionately hurts black patients

Female rats face sex bias too

There’s no evidence that a single ‘gay gene’ exists

Positive attitudes about aging may pay off in better health

What male bias in the mammoth fossil record says about the animal’s social groups

The man flu struggle might be real, says one researcher

Scientists may work to prevent bias, but they don’t always say so

The Bias Finders

Showdown at Sex Gap

University resources:

Project Implicit (Take an Implicit Association Tests)

Catalogue of Bias

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Treating gum disease after heart rhythm ablation reduces risk of AFib recurrence, study finds

by American Heart Association

teeth

Treating gum disease in the three months after a procedure to correct an irregular heartbeat known as atrial fibrillation (AFib) may lower oral inflammation and may reduce AFib recurrence, according to new research published today in the Journal of the American Heart Association .

According to the U.S. Centers for Disease Control and Prevention (CDC), about half of American adults ages 30 or older have some form of periodontal or gum disease , with the incidence increasing with age.

This study is among the first to investigate the potential impact of gum disease treatment on AFib. AFib is a condition in which the heart beats irregularly, increasing the risk of stroke by five-fold. More than 12 million people in the U.S. are expected to have AFib by 2030, according to the American Heart Association's 2024 Heart Disease and Stroke Statistics .

"Gum disease can be modified by dental intervention. Proper management of gum disease appears to improve the prognosis of AFib, and many people around the world could benefit from it," said lead study author Shunsuke Miyauchi, M.D., Ph.D., an assistant professor at the Health Service Center at Hiroshima University in Japan who engages in general cardiology, arrhythmia practice and research.

Researchers followed 97 patients who had undergone the non-surgical procedure to correct AFib (radiofrequency catheter ablation) and received treatment for gum inflammation , along with 191 ablation patients who did not receive treatment for gum disease. Catheter ablation is a procedure that uses radiofrequency energy to destroy a small area of heart tissue causing rapid and irregular heartbeats. This study found that an index measuring the severity of gum inflammation was associated with the return of AFib.

After the ablation procedure, during the average follow-up period of between 8.5 months to 2 years, researchers found:

  • AFib recurred among 24% of all participants throughout the follow-up period.
  • Patients with severe gum inflammation who had it treated after heart catheter ablation were 61% less likely to have a recurrence of AFib, compared to ablation patients who did not have treatment for severe gum inflammation.
  • Patients who had recurrences of AFib had more severe gum disease than those who did not have recurrences.
  • Having gum disease, being female, experiencing irregular heartbeat for more than two years and left atrial volume were predictors for AFib recurrences. Left atrial volume often leads to AFib recurrence as it includes thickening and scarring of connective tissues, Miyauchi explained.

Miyauchi noted, "While the main findings were consistent with their expectations, we were surprised how useful a quantitative index of gum disease, known as periodontal inflamed surface area or PISA, could be in cardiovascular clinical practice."

While the American Heart Association does not recognize oral health as a risk factor for heart disease , it recognizes that oral health can be an indicator of overall health and well-being. Bacteria from inflamed teeth and gums may travel through the bloodstream to the rest of the body, including the heart and brain. Chronic gum inflammation may be associated with other systemic health conditions, including coronary artery disease, stroke and Type 2 diabetes.

Study details and background:

  • A total of 288 adults (66% men; 34% women) being treated for AFib were enrolled in this study.
  • The single center study was conducted from April 1, 2020 to July 31, 2022, at Hiroshima University Hospital in Hiroshima, Japan, and all participants were Asian.
  • Enrollees were examined by a dentist before undergoing catheter ablation for AFib.

"We are now working on further research to reveal the mechanism underlying the relationship between gum disease and AFib," Miyauchi said.

The study's limitations include: a small number of patients enrolled from a single center; patients were not randomized to receive dental treatment; periodontal status was not followed up after the initial examination among the participants who did not receive gum disease treatment; and inflammatory markers were not reassessed after the ablation procedure.

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Scientists Pursue the Total Solar Eclipse with NASA Jet Planes

The April 8, 2024, total solar eclipse will produce stunning views across North America. While anyone along the eclipse path with a clear sky will see the spectacular event, the best view might be 50,000 feet in the air, aboard NASA’s WB-57 jet planes. That’s where a trio of NASA-funded teams are sending their scientific instruments to take measurements of the eclipse.

Two teams will image the Sun’s outer atmosphere – the corona – and a third will measure the ionosphere, the upper electrically charged layer of Earth’s atmosphere. This information will help scientists better understand the structure and temperature of the corona, the effects of the Sun on Earth’s atmosphere, and even aid in the search of asteroids that may orbit near the Sun.

During a total solar eclipse, the Moon perfectly blocks the bright face of the Sun, casting a small swath of Earth in darkness. With the Sun’s main light masked, the much dimmer solar corona becomes visible to the naked eye. This provides scientists a unique opportunity to study this mysterious region of the Sun. The brief blocking of sunlight also allows scientists to study how the Sun’s light affects Earth’s atmosphere.

In the past, solar eclipses have driven numerous scientific discoveries. For this solar eclipse, NASA is funding several scientific experiments – including the three using the WB-57s – to make measurements during the eclipse. NASA’s WB-57s fly much higher than commercial aircraft. This altitude allows the jets to fly above clouds – meaning no chance of missing the eclipse due to bad weather. Additionally, the height puts the jets above most of Earth’s atmosphere, which allows for the cameras to take crisper images and capture wavelengths, such as infrared light, that don’t make it to the ground. Since the planes can travel at 460 miles per hour, they’re also able to extend the time they spend in the Moon’s shadow. While the eclipse will last no more than four and a half minutes at any point on the ground, the planes will see an eclipse that lasts about 25 percent longer, over 6 minutes and 22 seconds.

A map of the contiguous U.S. shows the path of the 2024 total solar eclipse stretching on a narrow band from Texas to Maine.

“By extending the duration of totality, we’re increasing the duration of how much data we can acquire,” said Shadia Habbal, a researcher at the University of Hawaii who leads of one of the WB-57 eclipse experiments.

Habbal’s experiment will fly spectrometers – which record specific wavelengths of light and cameras. The instruments will measure the temperature and chemical composition of the corona and coronal mass ejections, which are large bursts of solar material. With this data, scientists aim to better understand the structure of the corona and identify the source of the solar wind, the constant stream of particles emitted by the Sun.

Habbal hopes the results of their study will help differentiate between different competing models of how the corona is heated. “This light is our best probe short of sticking a thermometer in the corona,” Habbal said.

For another team, led by Amir Caspi at the Southwest Research Institute in Boulder, Colorado, it’s not their first time chasing eclipses by plane. Caspi led a previous trailblazing experiment with the WB-57s during the 2017 total solar eclipse that crossed America from sea to sea. Images taken from the jet were used to study the structure of the corona.

That time was the first the jets had ever been used to study an eclipse. This time, an improved camera setup will allow measurements in more wavelengths from infrared to visible light that will hopefully reveal new information about structures in the middle and lower corona. The observations, taken with a high-resolution, high-speed camera, could also help study a dust ring that circles the Sun and help search for asteroids that may orbit near the Sun.

“There isn’t a lot of data of the Sun at some of the wavelengths we’ll be studying,” Caspi said.  “We don’t know what we’ll find, so it’s extra exciting to be making these measurements.”

A third experiment will study the effects of the Moon’s shadow on the ionosphere using an instrument called an ionosonde, which was designed at JHU APL. An ionosonde functions like a simple radar. The device sends out high-frequency radio signals and listens for their echoes rebounding off the ionosphere, which allows the researchers to measure how charged the ionosphere is.

“The eclipse basically serves as a controlled experiment,” said Bharat Kunduri, leader of the ionosphere project and a research assistant professor at Virginia Tech in Blacksburg, Virginia. “It gives us an opportunity to understand how changes in solar radiation can impact the ionosphere, which can in turn impact some of these technologies like radar and GPS that we rely on in our daily lives.”

By  Mara Johnson-Groh NASA’s Goddard Space Flight Center , Greenbelt, Md.

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Prestigious cancer research institute has retracted 7 studies amid controversy over errors

Dana-Farber Cancer Institute

Seven studies from researchers at the prestigious Dana-Farber Cancer Institute have been retracted over the last two months after a scientist blogger alleged that images used in them had been manipulated or duplicated.

The retractions are the latest development in a monthslong controversy around research at the Boston-based institute, which is a teaching affiliate of Harvard Medical School. 

The issue came to light after Sholto David, a microbiologist and volunteer science sleuth based in Wales, published a scathing post on his blog in January, alleging errors and manipulations of images across dozens of papers produced primarily by Dana-Farber researchers . The institute acknowledged errors and subsequently announced that it had requested six studies to be retracted and asked for corrections in 31 more papers. Dana-Farber also said, however, that a review process for errors had been underway before David’s post. 

Now, at least one more study has been retracted than Dana-Farber initially indicated, and David said he has discovered an additional 30 studies from authors affiliated with the institute that he believes contain errors or image manipulations and therefore deserve scrutiny.

The episode has imperiled the reputation of a major cancer research institute and raised questions about one high-profile researcher there, Kenneth Anderson, who is a senior author on six of the seven retracted studies. 

Anderson is a professor of medicine at Harvard Medical School and the director of the Jerome Lipper Multiple Myeloma Center at Dana-Farber. He did not respond to multiple emails or voicemails requesting comment. 

The retractions and new allegations add to a larger, ongoing debate in science about how to protect scientific integrity and reduce the incentives that could lead to misconduct or unintentional mistakes in research. 

The Dana-Farber Cancer Institute has moved relatively swiftly to seek retractions and corrections. 

“Dana-Farber is deeply committed to a culture of accountability and integrity, and as an academic research and clinical care organization we also prioritize transparency,” Dr. Barrett Rollins, the institute’s integrity research officer, said in a statement. “However, we are bound by federal regulations that apply to all academic medical centers funded by the National Institutes of Health among other federal agencies. Therefore, we cannot share details of internal review processes and will not comment on personnel issues.”

The retracted studies were originally published in two journals: One in the Journal of Immunology and six in Cancer Research. Six of the seven focused on multiple myeloma, a form of cancer that develops in plasma cells. Retraction notices indicate that Anderson agreed to the retractions of the papers he authored.

Elisabeth Bik, a microbiologist and longtime image sleuth, reviewed several of the papers’ retraction statements and scientific images for NBC News and said the errors were serious. 

“The ones I’m looking at all have duplicated elements in the photos, where the photo itself has been manipulated,” she said, adding that these elements were “signs of misconduct.” 

Dr.  John Chute, who directs the division of hematology and cellular therapy at Cedars-Sinai Medical Center and has contributed to studies about multiple myeloma, said the papers were produced by pioneers in the field, including Anderson. 

“These are people I admire and respect,” he said. “Those were all high-impact papers, meaning they’re highly read and highly cited. By definition, they have had a broad impact on the field.” 

Chute said he did not know the authors personally but had followed their work for a long time.

“Those investigators are some of the leading people in the field of myeloma research and they have paved the way in terms of understanding our biology of the disease,” he said. “The papers they publish lead to all kinds of additional work in that direction. People follow those leads and industry pays attention to that stuff and drug development follows.”

The retractions offer additional evidence for what some science sleuths have been saying for years: The more you look for errors or image manipulation, the more you might find, even at the top levels of science. 

Scientific images in papers are typically used to present evidence of an experiment’s results. Commonly, they show cells or mice; other types of images show key findings like western blots — a laboratory method that identifies proteins — or bands of separated DNA molecules in gels. 

Science sleuths sometimes examine these images for irregular patterns that could indicate errors, duplications or manipulations. Some artificial intelligence companies are training computers to spot these kinds of problems, as well. 

Duplicated images could be a sign of sloppy lab work or data practices. Manipulated images — in which a researcher has modified an image heavily with photo editing tools — could indicate that images have been exaggerated, enhanced or altered in an unethical way that could change how other scientists interpret a study’s findings or scientific meaning. 

Top scientists at big research institutions often run sprawling laboratories with lots of junior scientists. Critics of science research and publishing systems allege that a lack of opportunities for young scientists, limited oversight and pressure to publish splashy papers that can advance careers could incentivize misconduct. 

These critics, along with many science sleuths, allege that errors or sloppiness are too common , that research organizations and authors often ignore concerns when they’re identified, and that the path from complaint to correction is sluggish. 

“When you look at the amount of retractions and poor peer review in research today, the question is, what has happened to the quality standards we used to think existed in research?” said Nick Steneck, an emeritus professor at the University of Michigan and an expert on science integrity.

David told NBC News that he had shared some, but not all, of his concerns about additional image issues with Dana-Farber. He added that he had not identified any problems in four of the seven studies that have been retracted. 

“It’s good they’ve picked up stuff that wasn’t in the list,” he said. 

NBC News requested an updated tally of retractions and corrections, but Ellen Berlin, a spokeswoman for Dana-Farber, declined to provide a new list. She said that the numbers could shift and that the institute did not have control over the form, format or timing of corrections. 

“Any tally we give you today might be different tomorrow and will likely be different a week from now or a month from now,” Berlin said. “The point of sharing numbers with the public weeks ago was to make clear to the public that Dana-Farber had taken swift and decisive action with regard to the articles for which a Dana-Farber faculty member was primary author.” 

She added that Dana-Farber was encouraging journals to correct the scientific record as promptly as possible. 

Bik said it was unusual to see a highly regarded U.S. institution have multiple papers retracted. 

“I don’t think I’ve seen many of those,” she said. “In this case, there was a lot of public attention to it and it seems like they’re responding very quickly. It’s unusual, but how it should be.”

Evan Bush is a science reporter for NBC News. He can be reached at [email protected].

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Peer Review in Scientific Publications: Benefits, Critiques, & A Survival Guide

Jacalyn kelly.

1 Clinical Biochemistry, Department of Pediatric Laboratory Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada

Tara Sadeghieh

Khosrow adeli.

2 Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada

3 Chair, Communications and Publications Division (CPD), International Federation for Sick Clinical Chemistry (IFCC), Milan, Italy

The authors declare no conflicts of interest regarding publication of this article.

Peer review has been defined as a process of subjecting an author’s scholarly work, research or ideas to the scrutiny of others who are experts in the same field. It functions to encourage authors to meet the accepted high standards of their discipline and to control the dissemination of research data to ensure that unwarranted claims, unacceptable interpretations or personal views are not published without prior expert review. Despite its wide-spread use by most journals, the peer review process has also been widely criticised due to the slowness of the process to publish new findings and due to perceived bias by the editors and/or reviewers. Within the scientific community, peer review has become an essential component of the academic writing process. It helps ensure that papers published in scientific journals answer meaningful research questions and draw accurate conclusions based on professionally executed experimentation. Submission of low quality manuscripts has become increasingly prevalent, and peer review acts as a filter to prevent this work from reaching the scientific community. The major advantage of a peer review process is that peer-reviewed articles provide a trusted form of scientific communication. Since scientific knowledge is cumulative and builds on itself, this trust is particularly important. Despite the positive impacts of peer review, critics argue that the peer review process stifles innovation in experimentation, and acts as a poor screen against plagiarism. Despite its downfalls, there has not yet been a foolproof system developed to take the place of peer review, however, researchers have been looking into electronic means of improving the peer review process. Unfortunately, the recent explosion in online only/electronic journals has led to mass publication of a large number of scientific articles with little or no peer review. This poses significant risk to advances in scientific knowledge and its future potential. The current article summarizes the peer review process, highlights the pros and cons associated with different types of peer review, and describes new methods for improving peer review.

WHAT IS PEER REVIEW AND WHAT IS ITS PURPOSE?

Peer Review is defined as “a process of subjecting an author’s scholarly work, research or ideas to the scrutiny of others who are experts in the same field” ( 1 ). Peer review is intended to serve two primary purposes. Firstly, it acts as a filter to ensure that only high quality research is published, especially in reputable journals, by determining the validity, significance and originality of the study. Secondly, peer review is intended to improve the quality of manuscripts that are deemed suitable for publication. Peer reviewers provide suggestions to authors on how to improve the quality of their manuscripts, and also identify any errors that need correcting before publication.

HISTORY OF PEER REVIEW

The concept of peer review was developed long before the scholarly journal. In fact, the peer review process is thought to have been used as a method of evaluating written work since ancient Greece ( 2 ). The peer review process was first described by a physician named Ishaq bin Ali al-Rahwi of Syria, who lived from 854-931 CE, in his book Ethics of the Physician ( 2 ). There, he stated that physicians must take notes describing the state of their patients’ medical conditions upon each visit. Following treatment, the notes were scrutinized by a local medical council to determine whether the physician had met the required standards of medical care. If the medical council deemed that the appropriate standards were not met, the physician in question could receive a lawsuit from the maltreated patient ( 2 ).

The invention of the printing press in 1453 allowed written documents to be distributed to the general public ( 3 ). At this time, it became more important to regulate the quality of the written material that became publicly available, and editing by peers increased in prevalence. In 1620, Francis Bacon wrote the work Novum Organum, where he described what eventually became known as the first universal method for generating and assessing new science ( 3 ). His work was instrumental in shaping the Scientific Method ( 3 ). In 1665, the French Journal des sçavans and the English Philosophical Transactions of the Royal Society were the first scientific journals to systematically publish research results ( 4 ). Philosophical Transactions of the Royal Society is thought to be the first journal to formalize the peer review process in 1665 ( 5 ), however, it is important to note that peer review was initially introduced to help editors decide which manuscripts to publish in their journals, and at that time it did not serve to ensure the validity of the research ( 6 ). It did not take long for the peer review process to evolve, and shortly thereafter papers were distributed to reviewers with the intent of authenticating the integrity of the research study before publication. The Royal Society of Edinburgh adhered to the following peer review process, published in their Medical Essays and Observations in 1731: “Memoirs sent by correspondence are distributed according to the subject matter to those members who are most versed in these matters. The report of their identity is not known to the author.” ( 7 ). The Royal Society of London adopted this review procedure in 1752 and developed the “Committee on Papers” to review manuscripts before they were published in Philosophical Transactions ( 6 ).

Peer review in the systematized and institutionalized form has developed immensely since the Second World War, at least partly due to the large increase in scientific research during this period ( 7 ). It is now used not only to ensure that a scientific manuscript is experimentally and ethically sound, but also to determine which papers sufficiently meet the journal’s standards of quality and originality before publication. Peer review is now standard practice by most credible scientific journals, and is an essential part of determining the credibility and quality of work submitted.

IMPACT OF THE PEER REVIEW PROCESS

Peer review has become the foundation of the scholarly publication system because it effectively subjects an author’s work to the scrutiny of other experts in the field. Thus, it encourages authors to strive to produce high quality research that will advance the field. Peer review also supports and maintains integrity and authenticity in the advancement of science. A scientific hypothesis or statement is generally not accepted by the academic community unless it has been published in a peer-reviewed journal ( 8 ). The Institute for Scientific Information ( ISI ) only considers journals that are peer-reviewed as candidates to receive Impact Factors. Peer review is a well-established process which has been a formal part of scientific communication for over 300 years.

OVERVIEW OF THE PEER REVIEW PROCESS

The peer review process begins when a scientist completes a research study and writes a manuscript that describes the purpose, experimental design, results, and conclusions of the study. The scientist then submits this paper to a suitable journal that specializes in a relevant research field, a step referred to as pre-submission. The editors of the journal will review the paper to ensure that the subject matter is in line with that of the journal, and that it fits with the editorial platform. Very few papers pass this initial evaluation. If the journal editors feel the paper sufficiently meets these requirements and is written by a credible source, they will send the paper to accomplished researchers in the field for a formal peer review. Peer reviewers are also known as referees (this process is summarized in Figure 1 ). The role of the editor is to select the most appropriate manuscripts for the journal, and to implement and monitor the peer review process. Editors must ensure that peer reviews are conducted fairly, and in an effective and timely manner. They must also ensure that there are no conflicts of interest involved in the peer review process.

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Overview of the review process

When a reviewer is provided with a paper, he or she reads it carefully and scrutinizes it to evaluate the validity of the science, the quality of the experimental design, and the appropriateness of the methods used. The reviewer also assesses the significance of the research, and judges whether the work will contribute to advancement in the field by evaluating the importance of the findings, and determining the originality of the research. Additionally, reviewers identify any scientific errors and references that are missing or incorrect. Peer reviewers give recommendations to the editor regarding whether the paper should be accepted, rejected, or improved before publication in the journal. The editor will mediate author-referee discussion in order to clarify the priority of certain referee requests, suggest areas that can be strengthened, and overrule reviewer recommendations that are beyond the study’s scope ( 9 ). If the paper is accepted, as per suggestion by the peer reviewer, the paper goes into the production stage, where it is tweaked and formatted by the editors, and finally published in the scientific journal. An overview of the review process is presented in Figure 1 .

WHO CONDUCTS REVIEWS?

Peer reviews are conducted by scientific experts with specialized knowledge on the content of the manuscript, as well as by scientists with a more general knowledge base. Peer reviewers can be anyone who has competence and expertise in the subject areas that the journal covers. Reviewers can range from young and up-and-coming researchers to old masters in the field. Often, the young reviewers are the most responsive and deliver the best quality reviews, though this is not always the case. On average, a reviewer will conduct approximately eight reviews per year, according to a study on peer review by the Publishing Research Consortium (PRC) ( 7 ). Journals will often have a pool of reviewers with diverse backgrounds to allow for many different perspectives. They will also keep a rather large reviewer bank, so that reviewers do not get burnt out, overwhelmed or time constrained from reviewing multiple articles simultaneously.

WHY DO REVIEWERS REVIEW?

Referees are typically not paid to conduct peer reviews and the process takes considerable effort, so the question is raised as to what incentive referees have to review at all. Some feel an academic duty to perform reviews, and are of the mentality that if their peers are expected to review their papers, then they should review the work of their peers as well. Reviewers may also have personal contacts with editors, and may want to assist as much as possible. Others review to keep up-to-date with the latest developments in their field, and reading new scientific papers is an effective way to do so. Some scientists use peer review as an opportunity to advance their own research as it stimulates new ideas and allows them to read about new experimental techniques. Other reviewers are keen on building associations with prestigious journals and editors and becoming part of their community, as sometimes reviewers who show dedication to the journal are later hired as editors. Some scientists see peer review as a chance to become aware of the latest research before their peers, and thus be first to develop new insights from the material. Finally, in terms of career development, peer reviewing can be desirable as it is often noted on one’s resume or CV. Many institutions consider a researcher’s involvement in peer review when assessing their performance for promotions ( 11 ). Peer reviewing can also be an effective way for a scientist to show their superiors that they are committed to their scientific field ( 5 ).

ARE REVIEWERS KEEN TO REVIEW?

A 2009 international survey of 4000 peer reviewers conducted by the charity Sense About Science at the British Science Festival at the University of Surrey, found that 90% of reviewers were keen to peer review ( 12 ). One third of respondents to the survey said they were happy to review up to five papers per year, and an additional one third of respondents were happy to review up to ten.

HOW LONG DOES IT TAKE TO REVIEW ONE PAPER?

On average, it takes approximately six hours to review one paper ( 12 ), however, this number may vary greatly depending on the content of the paper and the nature of the peer reviewer. One in every 100 participants in the “Sense About Science” survey claims to have taken more than 100 hours to review their last paper ( 12 ).

HOW TO DETERMINE IF A JOURNAL IS PEER REVIEWED

Ulrichsweb is a directory that provides information on over 300,000 periodicals, including information regarding which journals are peer reviewed ( 13 ). After logging into the system using an institutional login (eg. from the University of Toronto), search terms, journal titles or ISSN numbers can be entered into the search bar. The database provides the title, publisher, and country of origin of the journal, and indicates whether the journal is still actively publishing. The black book symbol (labelled ‘refereed’) reveals that the journal is peer reviewed.

THE EVALUATION CRITERIA FOR PEER REVIEW OF SCIENTIFIC PAPERS

As previously mentioned, when a reviewer receives a scientific manuscript, he/she will first determine if the subject matter is well suited for the content of the journal. The reviewer will then consider whether the research question is important and original, a process which may be aided by a literature scan of review articles.

Scientific papers submitted for peer review usually follow a specific structure that begins with the title, followed by the abstract, introduction, methodology, results, discussion, conclusions, and references. The title must be descriptive and include the concept and organism investigated, and potentially the variable manipulated and the systems used in the study. The peer reviewer evaluates if the title is descriptive enough, and ensures that it is clear and concise. A study by the National Association of Realtors (NAR) published by the Oxford University Press in 2006 indicated that the title of a manuscript plays a significant role in determining reader interest, as 72% of respondents said they could usually judge whether an article will be of interest to them based on the title and the author, while 13% of respondents claimed to always be able to do so ( 14 ).

The abstract is a summary of the paper, which briefly mentions the background or purpose, methods, key results, and major conclusions of the study. The peer reviewer assesses whether the abstract is sufficiently informative and if the content of the abstract is consistent with the rest of the paper. The NAR study indicated that 40% of respondents could determine whether an article would be of interest to them based on the abstract alone 60-80% of the time, while 32% could judge an article based on the abstract 80-100% of the time ( 14 ). This demonstrates that the abstract alone is often used to assess the value of an article.

The introduction of a scientific paper presents the research question in the context of what is already known about the topic, in order to identify why the question being studied is of interest to the scientific community, and what gap in knowledge the study aims to fill ( 15 ). The introduction identifies the study’s purpose and scope, briefly describes the general methods of investigation, and outlines the hypothesis and predictions ( 15 ). The peer reviewer determines whether the introduction provides sufficient background information on the research topic, and ensures that the research question and hypothesis are clearly identifiable.

The methods section describes the experimental procedures, and explains why each experiment was conducted. The methods section also includes the equipment and reagents used in the investigation. The methods section should be detailed enough that it can be used it to repeat the experiment ( 15 ). Methods are written in the past tense and in the active voice. The peer reviewer assesses whether the appropriate methods were used to answer the research question, and if they were written with sufficient detail. If information is missing from the methods section, it is the peer reviewer’s job to identify what details need to be added.

The results section is where the outcomes of the experiment and trends in the data are explained without judgement, bias or interpretation ( 15 ). This section can include statistical tests performed on the data, as well as figures and tables in addition to the text. The peer reviewer ensures that the results are described with sufficient detail, and determines their credibility. Reviewers also confirm that the text is consistent with the information presented in tables and figures, and that all figures and tables included are important and relevant ( 15 ). The peer reviewer will also make sure that table and figure captions are appropriate both contextually and in length, and that tables and figures present the data accurately.

The discussion section is where the data is analyzed. Here, the results are interpreted and related to past studies ( 15 ). The discussion describes the meaning and significance of the results in terms of the research question and hypothesis, and states whether the hypothesis was supported or rejected. This section may also provide possible explanations for unusual results and suggestions for future research ( 15 ). The discussion should end with a conclusions section that summarizes the major findings of the investigation. The peer reviewer determines whether the discussion is clear and focused, and whether the conclusions are an appropriate interpretation of the results. Reviewers also ensure that the discussion addresses the limitations of the study, any anomalies in the results, the relationship of the study to previous research, and the theoretical implications and practical applications of the study.

The references are found at the end of the paper, and list all of the information sources cited in the text to describe the background, methods, and/or interpret results. Depending on the citation method used, the references are listed in alphabetical order according to author last name, or numbered according to the order in which they appear in the paper. The peer reviewer ensures that references are used appropriately, cited accurately, formatted correctly, and that none are missing.

Finally, the peer reviewer determines whether the paper is clearly written and if the content seems logical. After thoroughly reading through the entire manuscript, they determine whether it meets the journal’s standards for publication,

and whether it falls within the top 25% of papers in its field ( 16 ) to determine priority for publication. An overview of what a peer reviewer looks for when evaluating a manuscript, in order of importance, is presented in Figure 2 .

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How a peer review evaluates a manuscript

To increase the chance of success in the peer review process, the author must ensure that the paper fully complies with the journal guidelines before submission. The author must also be open to criticism and suggested revisions, and learn from mistakes made in previous submissions.

ADVANTAGES AND DISADVANTAGES OF THE DIFFERENT TYPES OF PEER REVIEW

The peer review process is generally conducted in one of three ways: open review, single-blind review, or double-blind review. In an open review, both the author of the paper and the peer reviewer know one another’s identity. Alternatively, in single-blind review, the reviewer’s identity is kept private, but the author’s identity is revealed to the reviewer. In double-blind review, the identities of both the reviewer and author are kept anonymous. Open peer review is advantageous in that it prevents the reviewer from leaving malicious comments, being careless, or procrastinating completion of the review ( 2 ). It encourages reviewers to be open and honest without being disrespectful. Open reviewing also discourages plagiarism amongst authors ( 2 ). On the other hand, open peer review can also prevent reviewers from being honest for fear of developing bad rapport with the author. The reviewer may withhold or tone down their criticisms in order to be polite ( 2 ). This is especially true when younger reviewers are given a more esteemed author’s work, in which case the reviewer may be hesitant to provide criticism for fear that it will damper their relationship with a superior ( 2 ). According to the Sense About Science survey, editors find that completely open reviewing decreases the number of people willing to participate, and leads to reviews of little value ( 12 ). In the aforementioned study by the PRC, only 23% of authors surveyed had experience with open peer review ( 7 ).

Single-blind peer review is by far the most common. In the PRC study, 85% of authors surveyed had experience with single-blind peer review ( 7 ). This method is advantageous as the reviewer is more likely to provide honest feedback when their identity is concealed ( 2 ). This allows the reviewer to make independent decisions without the influence of the author ( 2 ). The main disadvantage of reviewer anonymity, however, is that reviewers who receive manuscripts on subjects similar to their own research may be tempted to delay completing the review in order to publish their own data first ( 2 ).

Double-blind peer review is advantageous as it prevents the reviewer from being biased against the author based on their country of origin or previous work ( 2 ). This allows the paper to be judged based on the quality of the content, rather than the reputation of the author. The Sense About Science survey indicates that 76% of researchers think double-blind peer review is a good idea ( 12 ), and the PRC survey indicates that 45% of authors have had experience with double-blind peer review ( 7 ). The disadvantage of double-blind peer review is that, especially in niche areas of research, it can sometimes be easy for the reviewer to determine the identity of the author based on writing style, subject matter or self-citation, and thus, impart bias ( 2 ).

Masking the author’s identity from peer reviewers, as is the case in double-blind review, is generally thought to minimize bias and maintain review quality. A study by Justice et al. in 1998 investigated whether masking author identity affected the quality of the review ( 17 ). One hundred and eighteen manuscripts were randomized; 26 were peer reviewed as normal, and 92 were moved into the ‘intervention’ arm, where editor quality assessments were completed for 77 manuscripts and author quality assessments were completed for 40 manuscripts ( 17 ). There was no perceived difference in quality between the masked and unmasked reviews. Additionally, the masking itself was often unsuccessful, especially with well-known authors ( 17 ). However, a previous study conducted by McNutt et al. had different results ( 18 ). In this case, blinding was successful 73% of the time, and they found that when author identity was masked, the quality of review was slightly higher ( 18 ). Although Justice et al. argued that this difference was too small to be consequential, their study targeted only biomedical journals, and the results cannot be generalized to journals of a different subject matter ( 17 ). Additionally, there were problems masking the identities of well-known authors, introducing a flaw in the methods. Regardless, Justice et al. concluded that masking author identity from reviewers may not improve review quality ( 17 ).

In addition to open, single-blind and double-blind peer review, there are two experimental forms of peer review. In some cases, following publication, papers may be subjected to post-publication peer review. As many papers are now published online, the scientific community has the opportunity to comment on these papers, engage in online discussions and post a formal review. For example, online publishers PLOS and BioMed Central have enabled scientists to post comments on published papers if they are registered users of the site ( 10 ). Philica is another journal launched with this experimental form of peer review. Only 8% of authors surveyed in the PRC study had experience with post-publication review ( 7 ). Another experimental form of peer review called Dynamic Peer Review has also emerged. Dynamic peer review is conducted on websites such as Naboj, which allow scientists to conduct peer reviews on articles in the preprint media ( 19 ). The peer review is conducted on repositories and is a continuous process, which allows the public to see both the article and the reviews as the article is being developed ( 19 ). Dynamic peer review helps prevent plagiarism as the scientific community will already be familiar with the work before the peer reviewed version appears in print ( 19 ). Dynamic review also reduces the time lag between manuscript submission and publishing. An example of a preprint server is the ‘arXiv’ developed by Paul Ginsparg in 1991, which is used primarily by physicists ( 19 ). These alternative forms of peer review are still un-established and experimental. Traditional peer review is time-tested and still highly utilized. All methods of peer review have their advantages and deficiencies, and all are prone to error.

PEER REVIEW OF OPEN ACCESS JOURNALS

Open access (OA) journals are becoming increasingly popular as they allow the potential for widespread distribution of publications in a timely manner ( 20 ). Nevertheless, there can be issues regarding the peer review process of open access journals. In a study published in Science in 2013, John Bohannon submitted 304 slightly different versions of a fictional scientific paper (written by a fake author, working out of a non-existent institution) to a selected group of OA journals. This study was performed in order to determine whether papers submitted to OA journals are properly reviewed before publication in comparison to subscription-based journals. The journals in this study were selected from the Directory of Open Access Journals (DOAJ) and Biall’s List, a list of journals which are potentially predatory, and all required a fee for publishing ( 21 ). Of the 304 journals, 157 accepted a fake paper, suggesting that acceptance was based on financial interest rather than the quality of article itself, while 98 journals promptly rejected the fakes ( 21 ). Although this study highlights useful information on the problems associated with lower quality publishers that do not have an effective peer review system in place, the article also generalizes the study results to all OA journals, which can be detrimental to the general perception of OA journals. There were two limitations of the study that made it impossible to accurately determine the relationship between peer review and OA journals: 1) there was no control group (subscription-based journals), and 2) the fake papers were sent to a non-randomized selection of journals, resulting in bias.

JOURNAL ACCEPTANCE RATES

Based on a recent survey, the average acceptance rate for papers submitted to scientific journals is about 50% ( 7 ). Twenty percent of the submitted manuscripts that are not accepted are rejected prior to review, and 30% are rejected following review ( 7 ). Of the 50% accepted, 41% are accepted with the condition of revision, while only 9% are accepted without the request for revision ( 7 ).

SATISFACTION WITH THE PEER REVIEW SYSTEM

Based on a recent survey by the PRC, 64% of academics are satisfied with the current system of peer review, and only 12% claimed to be ‘dissatisfied’ ( 7 ). The large majority, 85%, agreed with the statement that ‘scientific communication is greatly helped by peer review’ ( 7 ). There was a similarly high level of support (83%) for the idea that peer review ‘provides control in scientific communication’ ( 7 ).

HOW TO PEER REVIEW EFFECTIVELY

The following are ten tips on how to be an effective peer reviewer as indicated by Brian Lucey, an expert on the subject ( 22 ):

1) Be professional

Peer review is a mutual responsibility among fellow scientists, and scientists are expected, as part of the academic community, to take part in peer review. If one is to expect others to review their work, they should commit to reviewing the work of others as well, and put effort into it.

2) Be pleasant

If the paper is of low quality, suggest that it be rejected, but do not leave ad hominem comments. There is no benefit to being ruthless.

3) Read the invite

When emailing a scientist to ask them to conduct a peer review, the majority of journals will provide a link to either accept or reject. Do not respond to the email, respond to the link.

4) Be helpful

Suggest how the authors can overcome the shortcomings in their paper. A review should guide the author on what is good and what needs work from the reviewer’s perspective.

5) Be scientific

The peer reviewer plays the role of a scientific peer, not an editor for proofreading or decision-making. Don’t fill a review with comments on editorial and typographic issues. Instead, focus on adding value with scientific knowledge and commenting on the credibility of the research conducted and conclusions drawn. If the paper has a lot of typographical errors, suggest that it be professionally proof edited as part of the review.

6) Be timely

Stick to the timeline given when conducting a peer review. Editors track who is reviewing what and when and will know if someone is late on completing a review. It is important to be timely both out of respect for the journal and the author, as well as to not develop a reputation of being late for review deadlines.

7) Be realistic

The peer reviewer must be realistic about the work presented, the changes they suggest and their role. Peer reviewers may set the bar too high for the paper they are editing by proposing changes that are too ambitious and editors must override them.

8) Be empathetic

Ensure that the review is scientific, helpful and courteous. Be sensitive and respectful with word choice and tone in a review.

Remember that both specialists and generalists can provide valuable insight when peer reviewing. Editors will try to get both specialised and general reviewers for any particular paper to allow for different perspectives. If someone is asked to review, the editor has determined they have a valid and useful role to play, even if the paper is not in their area of expertise.

10) Be organised

A review requires structure and logical flow. A reviewer should proofread their review before submitting it for structural, grammatical and spelling errors as well as for clarity. Most publishers provide short guides on structuring a peer review on their website. Begin with an overview of the proposed improvements; then provide feedback on the paper structure, the quality of data sources and methods of investigation used, the logical flow of argument, and the validity of conclusions drawn. Then provide feedback on style, voice and lexical concerns, with suggestions on how to improve.

In addition, the American Physiology Society (APS) recommends in its Peer Review 101 Handout that peer reviewers should put themselves in both the editor’s and author’s shoes to ensure that they provide what both the editor and the author need and expect ( 11 ). To please the editor, the reviewer should ensure that the peer review is completed on time, and that it provides clear explanations to back up recommendations. To be helpful to the author, the reviewer must ensure that their feedback is constructive. It is suggested that the reviewer take time to think about the paper; they should read it once, wait at least a day, and then re-read it before writing the review ( 11 ). The APS also suggests that Graduate students and researchers pay attention to how peer reviewers edit their work, as well as to what edits they find helpful, in order to learn how to peer review effectively ( 11 ). Additionally, it is suggested that Graduate students practice reviewing by editing their peers’ papers and asking a faculty member for feedback on their efforts. It is recommended that young scientists offer to peer review as often as possible in order to become skilled at the process ( 11 ). The majority of students, fellows and trainees do not get formal training in peer review, but rather learn by observing their mentors. According to the APS, one acquires experience through networking and referrals, and should therefore try to strengthen relationships with journal editors by offering to review manuscripts ( 11 ). The APS also suggests that experienced reviewers provide constructive feedback to students and junior colleagues on their peer review efforts, and encourages them to peer review to demonstrate the importance of this process in improving science ( 11 ).

The peer reviewer should only comment on areas of the manuscript that they are knowledgeable about ( 23 ). If there is any section of the manuscript they feel they are not qualified to review, they should mention this in their comments and not provide further feedback on that section. The peer reviewer is not permitted to share any part of the manuscript with a colleague (even if they may be more knowledgeable in the subject matter) without first obtaining permission from the editor ( 23 ). If a peer reviewer comes across something they are unsure of in the paper, they can consult the literature to try and gain insight. It is important for scientists to remember that if a paper can be improved by the expertise of one of their colleagues, the journal must be informed of the colleague’s help, and approval must be obtained for their colleague to read the protected document. Additionally, the colleague must be identified in the confidential comments to the editor, in order to ensure that he/she is appropriately credited for any contributions ( 23 ). It is the job of the reviewer to make sure that the colleague assisting is aware of the confidentiality of the peer review process ( 23 ). Once the review is complete, the manuscript must be destroyed and cannot be saved electronically by the reviewers ( 23 ).

COMMON ERRORS IN SCIENTIFIC PAPERS

When performing a peer review, there are some common scientific errors to look out for. Most of these errors are violations of logic and common sense: these may include contradicting statements, unwarranted conclusions, suggestion of causation when there is only support for correlation, inappropriate extrapolation, circular reasoning, or pursuit of a trivial question ( 24 ). It is also common for authors to suggest that two variables are different because the effects of one variable are statistically significant while the effects of the other variable are not, rather than directly comparing the two variables ( 24 ). Authors sometimes oversee a confounding variable and do not control for it, or forget to include important details on how their experiments were controlled or the physical state of the organisms studied ( 24 ). Another common fault is the author’s failure to define terms or use words with precision, as these practices can mislead readers ( 24 ). Jargon and/or misused terms can be a serious problem in papers. Inaccurate statements about specific citations are also a common occurrence ( 24 ). Additionally, many studies produce knowledge that can be applied to areas of science outside the scope of the original study, therefore it is better for reviewers to look at the novelty of the idea, conclusions, data, and methodology, rather than scrutinize whether or not the paper answered the specific question at hand ( 24 ). Although it is important to recognize these points, when performing a review it is generally better practice for the peer reviewer to not focus on a checklist of things that could be wrong, but rather carefully identify the problems specific to each paper and continuously ask themselves if anything is missing ( 24 ). An extremely detailed description of how to conduct peer review effectively is presented in the paper How I Review an Original Scientific Article written by Frederic G. Hoppin, Jr. It can be accessed through the American Physiological Society website under the Peer Review Resources section.

CRITICISM OF PEER REVIEW

A major criticism of peer review is that there is little evidence that the process actually works, that it is actually an effective screen for good quality scientific work, and that it actually improves the quality of scientific literature. As a 2002 study published in the Journal of the American Medical Association concluded, ‘Editorial peer review, although widely used, is largely untested and its effects are uncertain’ ( 25 ). Critics also argue that peer review is not effective at detecting errors. Highlighting this point, an experiment by Godlee et al. published in the British Medical Journal (BMJ) inserted eight deliberate errors into a paper that was nearly ready for publication, and then sent the paper to 420 potential reviewers ( 7 ). Of the 420 reviewers that received the paper, 221 (53%) responded, the average number of errors spotted by reviewers was two, no reviewer spotted more than five errors, and 35 reviewers (16%) did not spot any.

Another criticism of peer review is that the process is not conducted thoroughly by scientific conferences with the goal of obtaining large numbers of submitted papers. Such conferences often accept any paper sent in, regardless of its credibility or the prevalence of errors, because the more papers they accept, the more money they can make from author registration fees ( 26 ). This misconduct was exposed in 2014 by three MIT graduate students by the names of Jeremy Stribling, Dan Aguayo and Maxwell Krohn, who developed a simple computer program called SCIgen that generates nonsense papers and presents them as scientific papers ( 26 ). Subsequently, a nonsense SCIgen paper submitted to a conference was promptly accepted. Nature recently reported that French researcher Cyril Labbé discovered that sixteen SCIgen nonsense papers had been used by the German academic publisher Springer ( 26 ). Over 100 nonsense papers generated by SCIgen were published by the US Institute of Electrical and Electronic Engineers (IEEE) ( 26 ). Both organisations have been working to remove the papers. Labbé developed a program to detect SCIgen papers and has made it freely available to ensure publishers and conference organizers do not accept nonsense work in the future. It is available at this link: http://scigendetect.on.imag.fr/main.php ( 26 ).

Additionally, peer review is often criticized for being unable to accurately detect plagiarism. However, many believe that detecting plagiarism cannot practically be included as a component of peer review. As explained by Alice Tuff, development manager at Sense About Science, ‘The vast majority of authors and reviewers think peer review should detect plagiarism (81%) but only a minority (38%) think it is capable. The academic time involved in detecting plagiarism through peer review would cause the system to grind to a halt’ ( 27 ). Publishing house Elsevier began developing electronic plagiarism tools with the help of journal editors in 2009 to help improve this issue ( 27 ).

It has also been argued that peer review has lowered research quality by limiting creativity amongst researchers. Proponents of this view claim that peer review has repressed scientists from pursuing innovative research ideas and bold research questions that have the potential to make major advances and paradigm shifts in the field, as they believe that this work will likely be rejected by their peers upon review ( 28 ). Indeed, in some cases peer review may result in rejection of innovative research, as some studies may not seem particularly strong initially, yet may be capable of yielding very interesting and useful developments when examined under different circumstances, or in the light of new information ( 28 ). Scientists that do not believe in peer review argue that the process stifles the development of ingenious ideas, and thus the release of fresh knowledge and new developments into the scientific community.

Another issue that peer review is criticized for, is that there are a limited number of people that are competent to conduct peer review compared to the vast number of papers that need reviewing. An enormous number of papers published (1.3 million papers in 23,750 journals in 2006), but the number of competent peer reviewers available could not have reviewed them all ( 29 ). Thus, people who lack the required expertise to analyze the quality of a research paper are conducting reviews, and weak papers are being accepted as a result. It is now possible to publish any paper in an obscure journal that claims to be peer-reviewed, though the paper or journal itself could be substandard ( 29 ). On a similar note, the US National Library of Medicine indexes 39 journals that specialize in alternative medicine, and though they all identify themselves as “peer-reviewed”, they rarely publish any high quality research ( 29 ). This highlights the fact that peer review of more controversial or specialized work is typically performed by people who are interested and hold similar views or opinions as the author, which can cause bias in their review. For instance, a paper on homeopathy is likely to be reviewed by fellow practicing homeopaths, and thus is likely to be accepted as credible, though other scientists may find the paper to be nonsense ( 29 ). In some cases, papers are initially published, but their credibility is challenged at a later date and they are subsequently retracted. Retraction Watch is a website dedicated to revealing papers that have been retracted after publishing, potentially due to improper peer review ( 30 ).

Additionally, despite its many positive outcomes, peer review is also criticized for being a delay to the dissemination of new knowledge into the scientific community, and as an unpaid-activity that takes scientists’ time away from activities that they would otherwise prioritize, such as research and teaching, for which they are paid ( 31 ). As described by Eva Amsen, Outreach Director for F1000Research, peer review was originally developed as a means of helping editors choose which papers to publish when journals had to limit the number of papers they could print in one issue ( 32 ). However, nowadays most journals are available online, either exclusively or in addition to print, and many journals have very limited printing runs ( 32 ). Since there are no longer page limits to journals, any good work can and should be published. Consequently, being selective for the purpose of saving space in a journal is no longer a valid excuse that peer reviewers can use to reject a paper ( 32 ). However, some reviewers have used this excuse when they have personal ulterior motives, such as getting their own research published first.

RECENT INITIATIVES TOWARDS IMPROVING PEER REVIEW

F1000Research was launched in January 2013 by Faculty of 1000 as an open access journal that immediately publishes papers (after an initial check to ensure that the paper is in fact produced by a scientist and has not been plagiarised), and then conducts transparent post-publication peer review ( 32 ). F1000Research aims to prevent delays in new science reaching the academic community that are caused by prolonged publication times ( 32 ). It also aims to make peer reviewing more fair by eliminating any anonymity, which prevents reviewers from delaying the completion of a review so they can publish their own similar work first ( 32 ). F1000Research offers completely open peer review, where everything is published, including the name of the reviewers, their review reports, and the editorial decision letters ( 32 ).

PeerJ was founded by Jason Hoyt and Peter Binfield in June 2012 as an open access, peer reviewed scholarly journal for the Biological and Medical Sciences ( 33 ). PeerJ selects articles to publish based only on scientific and methodological soundness, not on subjective determinants of ‘impact ’, ‘novelty’ or ‘interest’ ( 34 ). It works on a “lifetime publishing plan” model which charges scientists for publishing plans that give them lifetime rights to publish with PeerJ, rather than charging them per publication ( 34 ). PeerJ also encourages open peer review, and authors are given the option to post the full peer review history of their submission with their published article ( 34 ). PeerJ also offers a pre-print review service called PeerJ Pre-prints, in which paper drafts are reviewed before being sent to PeerJ to publish ( 34 ).

Rubriq is an independent peer review service designed by Shashi Mudunuri and Keith Collier to improve the peer review system ( 35 ). Rubriq is intended to decrease redundancy in the peer review process so that the time lost in redundant reviewing can be put back into research ( 35 ). According to Keith Collier, over 15 million hours are lost each year to redundant peer review, as papers get rejected from one journal and are subsequently submitted to a less prestigious journal where they are reviewed again ( 35 ). Authors often have to submit their manuscript to multiple journals, and are often rejected multiple times before they find the right match. This process could take months or even years ( 35 ). Rubriq makes peer review portable in order to help authors choose the journal that is best suited for their manuscript from the beginning, thus reducing the time before their paper is published ( 35 ). Rubriq operates under an author-pay model, in which the author pays a fee and their manuscript undergoes double-blind peer review by three expert academic reviewers using a standardized scorecard ( 35 ). The majority of the author’s fee goes towards a reviewer honorarium ( 35 ). The papers are also screened for plagiarism using iThenticate ( 35 ). Once the manuscript has been reviewed by the three experts, the most appropriate journal for submission is determined based on the topic and quality of the paper ( 35 ). The paper is returned to the author in 1-2 weeks with the Rubriq Report ( 35 ). The author can then submit their paper to the suggested journal with the Rubriq Report attached. The Rubriq Report will give the journal editors a much stronger incentive to consider the paper as it shows that three experts have recommended the paper to them ( 35 ). Rubriq also has its benefits for reviewers; the Rubriq scorecard gives structure to the peer review process, and thus makes it consistent and efficient, which decreases time and stress for the reviewer. Reviewers also receive feedback on their reviews and most significantly, they are compensated for their time ( 35 ). Journals also benefit, as they receive pre-screened papers, reducing the number of papers sent to their own reviewers, which often end up rejected ( 35 ). This can reduce reviewer fatigue, and allow only higher-quality articles to be sent to their peer reviewers ( 35 ).

According to Eva Amsen, peer review and scientific publishing are moving in a new direction, in which all papers will be posted online, and a post-publication peer review will take place that is independent of specific journal criteria and solely focused on improving paper quality ( 32 ). Journals will then choose papers that they find relevant based on the peer reviews and publish those papers as a collection ( 32 ). In this process, peer review and individual journals are uncoupled ( 32 ). In Keith Collier’s opinion, post-publication peer review is likely to become more prevalent as a complement to pre-publication peer review, but not as a replacement ( 35 ). Post-publication peer review will not serve to identify errors and fraud but will provide an additional measurement of impact ( 35 ). Collier also believes that as journals and publishers consolidate into larger systems, there will be stronger potential for “cascading” and shared peer review ( 35 ).

CONCLUDING REMARKS

Peer review has become fundamental in assisting editors in selecting credible, high quality, novel and interesting research papers to publish in scientific journals and to ensure the correction of any errors or issues present in submitted papers. Though the peer review process still has some flaws and deficiencies, a more suitable screening method for scientific papers has not yet been proposed or developed. Researchers have begun and must continue to look for means of addressing the current issues with peer review to ensure that it is a full-proof system that ensures only quality research papers are released into the scientific community.

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  2. Scientific Research

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  3. Types of Research Methodology: Uses, Types & Benefits

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  4. Module 1: Introduction: What is Research?

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  5. Scientific Method

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  6. How Do the Different Types of Research Studies Work?

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VIDEO

  1. Basics of scientific research| Introduction to scientific research| lecture 1

  2. Stanford study shows promise in new approach to combat COVID

  3. Science Research Yields Student Study Tips

  4. Science for the 21st Century

  5. Your research can change the world

  6. HOW TO READ and ANALYZE A RESEARCH STUDY

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