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What is a contract research organization plus, top 5 cros to check out in 2022.

What is CRO?

What is a CRO?

A contract research organization, or CRO, is a company that provides outsourced research services to pharma companies and similar entities (also known as sponsors), supporting them in all aspects of developing and bringing new drugs/medical devices to market.

Keep reading to learn more about what CROs do, how they are different from clinical research organizations and why sponsors work with them. We’ve also included the top 5 CROs at the end and what you need to ask before signing the contract with a CRO.

What Do CROs Do?

What Do CROs Do

The main role of CROs is to carry out activities that the sponsoring pharmaceutical company cannot or chooses not to do in-house.

Pharmaceutical companies often count on both internal and external resources, but sometimes they need assistance with tasks that fall outside of their core capabilities. The main services that CROs typically provide are running clinical trials and managing data, although they can also help with other tasks like recruiting patients, protocol development, drug manufacturing, and more. CROs might themselves partner with other companies to provide robust services across the full spectrum of clinical trial activities. For example, CROs might partner with Power as a part of a multi-layered recruitment strategy for a trial.

The goal of a CRO is to provide pharmaceutical companies with the services and resources they need in order to get their new drugs approved by regulatory bodies like the FDA.

For example, if a company is working on developing a promising new drug, it may decide to hire a CRO to conduct clinical trials. The CRO would then be responsible for recruiting patients to participate in the trial as well as overseeing the trial itself and reporting the results back to the pharmaceutical company.

See the image below for some example services offered by CROs:

CRO Services

Are Contract Research Organizations the Same as Clinical Research Organizations?

Contract research organizations (CROs) are involved in all aspects of the clinical development process, from initial drug discovery through pre-clinical and clinical trials and regulatory approval.

They also often offer post-marketing support services such as phase-IV studies and safety surveillance. CROs may also help design a study, recruit patients for the study, perform laboratory tests on samples taken from patients in the study, monitor patient health during the study, analyze study data, prepare study reports, and present reports or summaries to the relevant regulatory bodies like the FDA.

A clinical research organization , on the other hand, is a specific type of CRO that specializes in conducting clinical trials for pharmaceutical companies and other organizations.

While some clinical research organizations do offer preclinical services, most focus primarily on phase-I through phase-IV studies for new drugs and medical devices. These trials are designed to test the safety and effectiveness of drugs, devices, or medical procedures in humans. The purpose of a clinical trial is to gather data that can be used to determine whether a drug or device should be approved for human use by the FDA.

Although clinical and contract research organizations may differ in some ways, they can both be contracted to conduct clinical trials.

Both types of organizations need to be certified by the FDA in the USA (or by the relevant regulatory agency in other countries). However, the certification process differs depending on the type of organization. For example, a clinical research organization must go through an extensive accreditation process before it can begin conducting clinical trials on humans. CROs may not necessarily need to pass this accreditation process if they are not involved in conducting clinical trials involving humans.

Why do sponsors work with CROs?

CROs play an important role in pharmaceutical and biotechnology product development. Here are just some of the reasons why sponsors (pharma, biotech and similar entities) may decide to work with CROs.

1. Specialized operations and cost control

Building and managing clinical trial operations completely in house is complicated, expensive and requires specialization in a multitude of areas. The entrance of CROs meant that pharmaceutical companies no longer needed to own all of their own scientific and clinical research facilities. Full-service CROs offer sponsors a complete set of solutions covering all requirements from before clinical trials even start, to launching the final drug or device on the market.

2. Improved access to technology

CROs offer various technology solutions to support sponsors in designing, conducting and managing clinical trials. Sponsors can choose to leverage these technologies depending on the needs of each unique study. Here are some example categories of technologies that sponsors may use: planning tools (protocol design, patient enrollment etc.), site management (activation, payments etc.), recruitment tools (e.g., Power ), trial management tools, clinical data analytics etc.

3. Ability to handle large amounts of data

There are a lot of moving pieces involved in successfully running a clinical trial. CROs are often used by pharmaceutical companies because of their ability to handle large amounts of data in a short amount of time.

4. Handling regulatory affairs (i.e., following FDA guidelines)

CROs typically have experience working with regulatory agencies such as the Food and Drug Administration (FDA). The FDA regulates the entirety of clinical drug trials, from design to implementation and final analysis. This means that CROs must work within the FDA’s guidelines when conducting any type of clinical trial. It also means that CROs can help pharmaceutical companies get their products to the market faster, as they do not need to hire internal experts specializing in these stringent and ever-changing regulations.

5. Multi-disciplinary expertise leading to quicker and more effective trials

CROs have access to a large pool of employees specialized in different areas, which means that they can provide pharmaceutical companies with the appropriate expertise needed to complete any type of clinical trial quickly and effectively.

Another benefit of contracting an outside supplier for research is that the contracting company does not have to hire someone internally who is up-to-date on all the latest trends and regulations regarding the product development process (thereby avoiding potentially long delays for training). Independent third-party contractors are often more experienced than in-house employees in terms of familiarity with clinical trials and regulatory compliance.

What Are The Top CROs in 2022?

The contract research organization (CRO) industry is rapidly growing, and it's easy to see why due to the roles they fulfill in pharmaceutical and biomedical research. As of 2022, there are over 2,700 CROs in the US and that number is growing.

The following list identifies some of the top contract research organizations (CROs) in 2022:

IQVIA is a healthcare technology company providing integrated services in clinical research, market access, and health outcomes. It works with pharmaceutical companies to develop new medicines and therapies for the treatment of diseases including cancer, diabetes, heart disease, hepatitis C, and HIV/AIDS.

IQVIA provides clinical trial support services through its subsidiary Quintiles Transnational Holdings Inc., which was formed in 2017 when Quintiles Transnational merged with IMS Health Holdings Incorporated.

2. Labcorp Drug Development

Labcorp Drug Development, formerly Covance, is a contract research organization that offers drug development, clinical trial, and laboratory services to the pharmaceutical industry. The company's mission is to help advance patient care by providing clients with high-quality services and solutions.

Labcorp was founded in 1996 and has since grown into one of the world's largest CROs, with over 40 offices worldwide. In addition to its global presence, Labcorp also maintains a strong presence in the USA, which is one of the largest national markets in the pharmaceutical industry.

3. Pharmaceutical Product Development (PPD)

Pharmaceutical Product Development, or PPD for short, is an international company known for developing drug delivery systems and pharmaceuticals to help patients around the world.

The company has been working in the pharmaceutical industry since 1985 and operates in numerous countries. Their headquarters are located in North Carolina, U.S.A., but they also have offices in Europe, Asia, Africa, and South America.

ICON offers a full range of consulting, clinical development and commercialisation services to pharma, biotech, medical device and government organizations. ICON has a global team of experts and extensive experience in a wide range of therapeutic areas.

ICON was founded in Dublin, Ireland in 1990 and has offices in 46 countries worldwide.

Medpace provides full-service clinical development services to biopharma and medical device sponsors. Founded in 1992, they have always held to a model of providing full-service clinical trial outsourcing. Medpace operates in 6 continents and has medical, operational, and regulatory specialists with country-specific expertise.

CROs in the Healthcare Industry - What You Need to Ask Before Signing the Contract

1. Get information from multiple sources. It's important to gather as much information as possible before making any decisions. The website of the CRO itself will not tell the whole story; it is a good idea to look for real reviews and feedback from other companies who have contracted the CRO to which you are considering outsourcing tasks.

2. Make sure that the CRO you are considering has an established track record of success with clients.

3. Check that the CRO has an active online presence and transparent contact information so you can contact them and research them further before signing anything.

4. Check that the company is up-to-date with regulatory standards and accreditations. These are renewed frequently as this is a rapidly changing industry, so verify that the CRO in question has up-to-date authorization and accreditation for the specific tasks you are considering contracting them for. If you can’t find this information on the website, contact them to get clear answers.

5. Make sure that the CRO has a good reputation among other firms in the industry as well as among current and past employees. A large number of sub-par reviews or complaints is a red flag, as are complaints by employees about protocols not being followed, internal uncleanliness or disorganization, etc.

6. Verify that the CRO has expertise in the specific task you wish to outsource! This may seem obvious, but just because a given CRO is world-renowned in conducting clinical trials, this does not mean they will be experts in analyzing your specific data. You should contract a contract research organization specializing in the tasks you will give them.

CROs play important roles in pharmaceutical and biotechnology product development. They essentially manage every aspect of the clinical research process while also providing access to state-of-the-art technology and facilities, thus also keeping costs down for the sponsor. If you are looking for a CRO to partner with to streamline or enhance your research, development, or clinical trial processes, a little bit of research to understand what they are capable of and what tasks they are specialized in will help you make an informed decision.

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The advantage of full-service agencies lies not only within their ability to offer end-to-end research solutions but also within the expertise required to understand and execute the entire research process.

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Founded 2017 | 320 employees, brad larson, founder and ceo.

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Founded 1988 | 400+ employees, mohit gour, evp.

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Phone 1-212-653-8750 www.ovationmr.com

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Radius Global Market Research

Founded 1960 | 150 employees, jamie myers, executive director.

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Phone 1-212-633-1100 radius-global.com

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Research America Market Research Solutions

Founded 1985 | 300 employees, robert porter, ceo.

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Phone 1-610-356-1800 www.ResearchAmericaInc.com

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Founded 1979 | 40 employees, david rothstein, ceo.

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Phone 1-203-653-4221 www.rtiresearch.com

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Founded 2008 | 50 employees, paul bragan, managing partner, nathan richter, managing partner.

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As a research company, Forrester has helped technology, marketing, sales, customer experience, and product executives see around corners and take decisive action for more than 35 years, from an objective point of view . View our upcoming Planned Research . Signature Forrester research includes:

The Customer-Obsessed Enterprise

Forrester pioneered the concept of customer obsession more than a decade ago, demonstrating that customer-obsessed operations are customer-led, insights-driven, fast, and connected. Our research proves that putting the customer at the center of your leadership, strategy, and operations results in the most efficient path to growth, happy employees, and satisfied customers.

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Clients have trusted the transparent methodology of Forrester Wave evaluations for more than 18 years to support vendor selection. Each Forrester Wave provides a simple visual evaluation of leading providers in specific market sectors, based on a robust analysis of their current offerings and strategies. Technology and service provider clients use Forrester Wave evaluations to understand current market drivers, what’s influencing those drivers, and their competitive position.

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Data And Analytics

Forrester Decisions and Forrester Market Insights services include rich Forrester data. Understand your customers and benchmark your CX performance through the Customer Experience Index (CX Index™) and gain broad views of consumer behaviors and business expectations in the buying process.

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Certification courses help you deepen your understanding of Forrester research through on-demand learning. Use certification as a way to align your team through a common vocabulary, approach, and way of working. Relevant certification courses are included as a part of all Forrester Decisions services.

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Expand the impact of analyst relations (AR) through a curated community with the Analyst Relations Council , a thriving global network of 300 analyst relations professionals. For more than 17 years, the AR Council has provided a place where you can collaborate on strategy, validate ideas, and spark inspiration with a group of like-minded peers.

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Serving the NIH Community

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Organizational Information

Explore the ORS history and organizational structure​

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View ORS leadership and programmatic offices

Program and Employee Services

Work-life balance programs and services

Security & Emergency Response

Security and life safety policy and operations

Scientific Resources

Scientific resources and regulation management

Communication & Outreach

Executive communication and outreach support

Office of Administrative Management

Administrative management support & services

Office of Budget and Finance

Budgetary and financial management

Office of Innovation and Information Technology

IT management & software development

​​​​​​​​​​​​​​​​The Office of Research Services (ORS) provides responsive and dependable support to the NIH research mission by coordinating, directing, and delivering scientific and regulatory expertise, public safety and security services ​, and  employee amenities  that enrich the NIH community. ​

We are dedicated ​​to continuous improvement, ​​innovation, ​transparency, ​and data-based decision making ​that is aligned with and driven by the needs of the NIH mission. ​​​​ORS works across organizational boundaries to supply seamless services that positively impact every interaction with customers throughout the NIH community.​​

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Mission | Vision | Core Values

  • ORS is committed to safety, security, collaboration, excellence and innovation. We practice an inclusive approach towards executing the actions necessary to acheive our mission, vision, and core values.

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ORS oversees an exemplary physical and service infrastructure that responds to the priorities of NIH leadership, employees, patients and partner communities.

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Office of the Director

  • The ORS Office of the Director establishes and implements policy while allocating the resources required to support NIH’s research mission and programmatic goals.​ ​

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Our ORS Community

​Across ORS, we recognize the tremendous significance of our collaborations, connections, and interactions with colleagues.​​

ORS Reports

ORS continuously strives to seamlessly deliver on its mission, exceed expectations, and evolve with changing requirements. To learn more about our successes and the ways we partner with the NIH research community, view the publications listed below.  

ORS Plan Front Page

2021 - 2026 ORS Strategic Plan

The 2021-2026 ORS Strategic Plan positions us to plan our future and anticipate partner needs based on collaboration, service excellence, and a steadfast commitment to high performance. 

​​ 2021-2026 ORS Strategic Plan  (NIH Staff Only)​​

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Our Story: Implementing the ORS Strategic Plan

Discover how the challenges of the pandemic inspired ORS to become an even more trusted partner and model of service excellence. 

Three ORS Goals

Five-Year Strategic Goals: An Integrated Approach​​

Our committment to partnership, service evolution, and organizational advancement is  crucial to the success of our strategic plan and  will guide ORS priorities over the next 5 years.

ORS Annual Report 2022

2022 ORS Annual Report

​The ORS Annual Report highlights our accomplishments and the ways we partner with the NIH research community to advance human health​.

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  4. Why research? Exploring the reasons for The Education Hub’s raison d

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    As of 2022, there are over 2,700 CROs in the US and that number is growing. The following list identifies some of the top contract research organizations (CROs) in 2022: 1. IQVIA. IQVIA is a healthcare technology company providing integrated services in clinical research, market access, and health outcomes.

  3. What is Research? Definition, Types, Methods and Process

    Research is defined as a meticulous and systematic inquiry process designed to explore and unravel specific subjects or issues with precision. This methodical approach encompasses the thorough collection, rigorous analysis, and insightful interpretation of information, aiming to delve deep into the nuances of a chosen field of study.

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  5. 21 Top Full-Service Research Companies in 2021 - Quirks.com

    Our extensive research skills encompass voice of the customer, satisfaction, decision-making, evaluating products and services, competitors and more. Let’s discuss your specific needs, ensuring your initiatives are effectively executed. Call for free consultation. Phone 1-847-506-0033. www.justthefacts.com.

  6. Research Service - an overview | ScienceDirect Topics

    Research services are therefore specific to supporting research processes and tools, including the grid. They should include collaboration with experts and peers, encapsulation of complex procedures for non-experts (possibly using some form of workflow technology) to facilitate growth of interdisciplinary sciences and aids for results publication and proposal writing.

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    Online samples. Your next breakthrough needs a market research panel designed for faster, more consistent, and higher quality insights. With our proprietary online samples, you can get insights from any audience around the world and accurately track trends and shifts in your market over time. Choose any target audience and we’ll give you ...

  8. List of Top Market Research Services 2024 - TrustRadius

    Qualtrics. 170 reviews. Has pricing. Qualtrics is software for advanced quantitative and qualitative research to design products that satisfy customers, increase market share, and build enduring brands. The platform brings sophisticated quant and qual research together with analytics in a single platform. 2.

  9. Gain Insights That Accelerate Growth With Forrester Research

    We know that customer obsession is the best path to revenue growth, profitability growth, customer retention, and employee engagement. Each Forrester Decisions service includes signature customer obsession research along with tools to make customer obsession a reality at your organization. Built for you. Each of the Forrester Decisions services ...

  10. ORS About ORS - National Institutes of Health

    The Office of Research Services (ORS) provides responsive and dependable support to the NIH research mission by coordinating, directing, and delivering scientific and regulatory expertise, public safety and security services , andemployee amenitiesthat enrich the NIH community. We are dedicated to continuous improvement, innovation ...