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Powerpoint Templates and Google slides for Database

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If you require a professional template with great design, then this Database Management System Powerpoint PPT Template Bundles is an ideal fit for you. Deploy it to enthrall your audience and increase your presentation threshold with the right graphics, images, and structure. Portray your ideas and vision using seventeen slides included in this complete deck. This template is suitable for expert discussion meetings presenting your views on the topic. With a variety of slides having the same thematic representation, this template can be regarded as a complete package. It employs some of the best design practices, so everything is well-structured. Not only this, it responds to all your needs and requirements by quickly adapting itself to the changes you make. This PPT slideshow is available for immediate download in PNG, JPG, and PDF formats, further enhancing its usability. Grab it by clicking the download button.

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This complete presentation has PPT slides on wide range of topics highlighting the core areas of your business needs. It has professionally designed templates with relevant visuals and subject driven content. This presentation deck has total of fourty four slides. Get access to the customizable templates. Our designers have created editable templates for your convenience. You can edit the color, text and font size as per your need. You can add or delete the content if required. You are just a click to away to have this ready-made presentation. Click the download button now.

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If you require a professional template with great design, then this Relational Database Powerpoint Ppt Template Bundles is an ideal fit for you. Deploy it to enthrall your audience and increase your presentation threshold with the right graphics, images, and structure. Portray your ideas and vision using eighteen slides included in this complete deck. This template is suitable for expert discussion meetings presenting your views on the topic. With a variety of slides having the same thematic representation, this template can be regarded as a complete package. It employs some of the best design practices, so everything is well structured. Not only this, it responds to all your needs and requirements by quickly adapting itself to the changes you make. This PPT slideshow is available for immediate download in PNG, JPG, and PDF formats, further enhancing its usability. Grab it by clicking the download button.

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Deliver a credible and compelling presentation by deploying this Database Relationship Diagram Powerpoint Ppt Template Bundles. Intensify your message with the right graphics, images, icons, etc. presented in this complete deck. This PPT template is a great starting point to convey your messages and build a good collaboration. The twelve slides added to this PowerPoint slideshow helps you present a thorough explanation of the topic. You can use it to study and present various kinds of information in the form of stats, figures, data charts, and many more. This Database Relationship Diagram Powerpoint Ppt Template Bundles PPT slideshow is available for use in standard and widescreen aspects ratios. So, you can use it as per your convenience. Apart from this, it can be downloaded in PNG, JPG, and PDF formats, all completely editable and modifiable. The most profound feature of this PPT design is that it is fully compatible with Google Slides making it suitable for every industry and business domain.

Deliver a credible and compelling presentation by deploying this Software Upgrade Depicting Database Smartphone Progress Illustrating. Intensify your message with the right graphics, images, icons, etc. presented in this complete deck. This PPT template is a great starting point to convey your messages and build a good collaboration. The twelve slides added to this PowerPoint slideshow helps you present a thorough explanation of the topic. You can use it to study and present various kinds of information in the form of stats, figures, data charts, and many more. This Software Upgrade Depicting Database Smartphone Progress Illustrating PPT slideshow is available for use in standard and widescreen aspects ratios. So, you can use it as per your convenience. Apart from this, it can be downloaded in PNG, JPG, and PDF formats, all completely editable and modifiable. The most profound feature of this PPT design is that it is fully compatible with Google Slides making it suitable for every industry and business domain.

If you require a professional template with great design, then this Cloud Database Powerpoint Ppt Template Bundles is an ideal fit for you. Deploy it to enthrall your audience and increase your presentation threshold with the right graphics, images, and structure. Portray your ideas and vision using eleven slides included in this complete deck. This template is suitable for expert discussion meetings presenting your views on the topic. With a variety of slides having the same thematic representation, this template can be regarded as a complete package. It employs some of the best design practices, so everything is well-structured. Not only this, it responds to all your needs and requirements by quickly adapting itself to the changes you make. This PPT slideshow is available for immediate download in PNG, JPG, and PDF formats, further enhancing its usability. Grab it by clicking the download button.

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If you require a professional template with great design, then this Incident Process Average Time Database Developer Planning is an ideal fit for you. Deploy it to enthrall your audience and increase your presentation threshold with the right graphics, images, and structure. Portray your ideas and vision using twelve slides included in this complete deck. This template is suitable for expert discussion meetings presenting your views on the topic. With a variety of slides having the same thematic representation, this template can be regarded as a complete package. It employs some of the best design practices, so everything is well-structured. Not only this, it responds to all your needs and requirements by quickly adapting itself to the changes you make. This PPT slideshow is available for immediate download in PNG, JPG, and PDF formats, further enhancing its usability. Grab it by clicking the download button.

If you require a professional template with great design, then this Backup Icon Restoration Business Document Database Storage is an ideal fit for you. Deploy it to enthrall your audience and increase your presentation threshold with the right graphics, images, and structure. Portray your ideas and vision using twelve slides included in this complete deck. This template is suitable for expert discussion meetings presenting your views on the topic. With a variety of slides having the same thematic representation, this template can be regarded as a complete package. It employs some of the best design practices, so everything is well-structured. Not only this, it responds to all your needs and requirements by quickly adapting itself to the changes you make. This PPT slideshow is available for immediate download in PNG, JPG, and PDF formats, further enhancing its usability. Grab it by clicking the download button.

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Enthrall your audience with this Automation For Customer Database Management Powerpoint Presentation Slides. Increase your presentation threshold by deploying this well-crafted template. It acts as a great communication tool due to its well-researched content. It also contains stylized icons, graphics, visuals etc, which make it an immediate attention-grabber. Comprising sixty six slides, this complete deck is all you need to get noticed. All the slides and their content can be altered to suit your unique business setting. Not only that, other components and graphics can also be modified to add personal touches to this prefabricated set.

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Deliver an informational PPT on various topics by using this CRM Digital Transformation Toolkit Powerpoint Presentation Slides. This deck focuses and implements best industry practices, thus providing a birds-eye view of the topic. Encompassed with one hunderd twenty slides, designed using high-quality visuals and graphics, this deck is a complete package to use and download. All the slides offered in this deck are subjective to innumerable alterations, thus making you a pro at delivering and educating. You can modify the color of the graphics, background, or anything else as per your needs and requirements. It suits every business vertical because of its adaptable layout.

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CS44800: Introduction to Database Systems, Spring 2019

Lecture Schedule

Chapter 1 - Introduction ( ppt / pdf )

Chapter 2 -Database System Concepts and Architecture ( ppt / pdf )

Chapter 13 - Disk Storage, Basic File Structures and Hashing ( ppt )

Chapter 14 - Indexing Structures for Files ( ppt )

Chapter 3 - Data Modeling Using the Entity Relationship (ER) Model ( ppt / pdf )

• Hierarchical model-slides
• Network Model-slides
• Handout on Natural and Outer Joins & Relational Calculus

Chapter 6 - The Relational Algebra and Calculus ( ppt / pdf )

Chapter 7 - Relational Database Design by ER-and EERR-to-Relational Mapping ( ppt / pdf )

Chapter 15 - Algorithms for Query Processing and Optimization ( ppt )

Chapter 8 - SQL-99: Schema Definition, Constraints, and Queries and Views ( ppt )

• JDBC Tutorial
• PL/SQL Tutorial

Chapter 10 - Functional Dependencies and Normalization for Relational Databases ( ppt )

• Example of proving loss less join
• Normalization and lossless joins and FD preservations

Chapter 12 - Practical Database Design Methodology and Use of UML Diagrams ( ppt )

Chapter 16 - Practical Database Design and Tuning ( ppt )

• Concurrency Control in Database Systems , Bharat Bhargava, IEEE Trans on Knowledge and Data Engineering,11(1), Jan.-Feb. 1999
• The Transaction Concept: Virtues and Limitations , Jim Gray, VLDB, 1981
• 2PL and Conflict Graph. ( pdf )
• Locking-Serializability. ( pdf )
• Optimistic-timestamps-Failure-Commitment. ( pdf )
• It will help you learn about CC ideas on 2PL, optimistic, time stamps and about transaction failures to help you do the homework. You may read the papers on CC under handouts and check sections 2 up to 2.3.2. ( pdf )
• You may read slides on chapter 21 (7th edition) up to slides 21-22 and then 27-29 for answers to homework. ( pdf )
• Logs, failures, serializability is discussed in slides for chapter 20. ( pdf )
• Concurrency Control in Database Systems, Bharat Bhargava, IEEE Trans on Knowledge and Data Engineering,11(1), Jan.-Feb. 1999. ( pdf )
• The Transaction Concept: Virtues and Limitations , Jim Gray, VLDB, 1981. ( pdf )

Chapter 19 - Database Recovery Techniques ( ppt )

• Feature analysis of selected database recovery techniques, Bharat Bhargava and Leszek Lilien, Proceedings of the May 4-7, 1981, National Computer Conference . ACM, 1981.( pdf )
• Secure Data Warehouse - Privacy

Chapter 24 - Enhanced Data Models for Advanced Applications ( ppt )

• Introduction to Cloud Computing
• Privacy and Identity Management in Cloud Computing
• Complete Tutorial

Chapter 26 - Web Database Programming using PHP ( ppt )

Chapter 27 - XML-Extensible Markup Language ( ppt )

Chapter 29 - Overview of Data Warehousing and OLAP ( ppt )

Chapter 30 - Emerging Database Technologies and Applications ( ppt )

CS44800, Spring 2019 Purdue University, Computer Science Department

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11 Powerful DBMS PPTs to Accelerate Your Learning Journey in Database Management Systems

Table of Contents

Learn Database Management Systems (DBMS PPTs)

Are you ready to embark on a journey into the world of Database Management Systems (DBMS)? Whether you’re a student, a professional, or simply someone intrigued by the inner workings of databases, having access to high-quality learning resources is essential. In this article, we present 11 powerful DBMS PowerPoint presentations (PPTs) that will supercharge your understanding of DBMS concepts and accelerate your learning process. So, let’s dive in and explore these invaluable resources together.

1. DBMS – Introduction to Database Management Systems

In this comprehensive PPT, we lay the foundation by providing an overview of Database Management Systems. From the basics of data storage to the advantages of using a DBMS, this presentation sets the stage for your DBMS journey.

Download Introduction to DBMS PPT

2. DBMS – Data Models

Understanding data models is crucial for effective database management. This PPT delves into various data models, such as hierarchical, network, and relational models, offering insights into their strengths and weaknesses. Gain a solid understanding of the different data models and their applications.

Download Data Models PPT

3. DBMS – Data Abstraction Techniques

Data abstraction is a fundamental concept in DBMS that enables users to interact with databases without worrying about the underlying complexities. This presentation explores data abstraction techniques, including the three levels of data abstraction: physical, logical, and view levels.

Download Data Abstraction Technique PPT

4. DBMS – Database Architecture

Get ready to explore the inner workings of a DBMS with this enlightening PPT on database architecture. Discover the components of a DBMS, such as the data dictionary, query processor, and storage manager. Gain insights into how these components work together to ensure efficient data management.

Download Database Architecture PPT

5. DBMS – Database Design & Entity Relationship – ER Model

Effective database design is crucial for building robust and efficient systems. This presentation focuses on the Entity Relationship (ER) model, a popular approach to database design. Learn how to identify entities, relationships, and attributes, and create an ER diagram to represent the database structure.

Download Database design & ER Model PPT

6. DBMS – ER Design Issues

As you delve deeper into ER modeling, you’ll encounter various design challenges. This PPT addresses common issues such as entity generalization, specialization, and aggregation. Master these concepts to create well-structured databases that accurately represent real-world scenarios.

Download ER Design Issues PPT

7. DBMS – Enhanced / Extended ER Model

The Enhanced/Extended ER model takes ER modeling to the next level by introducing additional concepts and constructs. Explore this powerful extension through this informative presentation, which covers topics like weak entities, ternary relationships, and specialization constraints.

Download Extended ER Model PPT

8. DBMS – Relational Data Model

The relational data model is widely used in modern database systems. This PPT provides a comprehensive overview of the relational model, including key concepts like relations, attributes, and integrity constraints. Understand how data is organized and manipulated in a relational database.

Download RDBMS PPT

9. DBMS – Conversion of ER Model to Relational Model

Transforming an ER model into a relational model can be a complex task. However, with this presentation’s guidance, you’ll learn systematic methods for converting ER diagrams to relational schemas. Master the art of mapping entities, relationships, and attributes into tables, keys, and relationships.

Download PPT for Concerson of ER Model to Relational Data Model

10. DBMS – Relational Algebra

Relational algebra serves as the foundation for manipulating and querying data in a relational database. This PPT explores the core operations of relational algebra, including selection, projection, join, and set operations. Enhance your query-building skills and unleash the power of relational databases.

Download Relational Alegebra PPT

11. DBMS – Different Types of Joins

Join operations are essential for combining data from multiple tables. In this final PPT, we focus on different types of joins, such as inner join, outer join, and self-join. Understand the nuances of each join type and leverage them to extract meaningful insights from your database.

Download PPT on Joins

If you’re seeking visual content to complement your learning experience, consider exploring the DBMS tutorials available on YouTube, particularly those recommended by NPTEL lecture videos. These tutorials offer a captivating way to grasp the intricacies of DBMS, combining informative explanations with engaging visuals. Adding this dynamic element to your learning journey can further enhance your understanding and make the process even more enjoyable.

In conclusion, these 11 powerful DBMS PPTs offer a wealth of knowledge and guidance for your learning journey in Database Management Systems. From understanding the core concepts to mastering advanced topics, these presentations will empower you to become a confident DBMS practitioner. So, start exploring these resources, dive deep into the world of databases, and unlock new possibilities in data management.

Remember, knowledge is power, and with these DBMS PPTs, you’re on the path to unlocking the full potential of Database Management Systems!

*Disclaimer: This article is for informational purposes only. The PPTs mentioned in this article may be available through various educational platforms and websites. Ensure to respect copyright laws and terms of use when accessing and utilizing these resources.

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Present Your Data Like a Pro

• Joel Schwartzberg

Demystify the numbers. Your audience will thank you.

While a good presentation has data, data alone doesn’t guarantee a good presentation. It’s all about how that data is presented. The quickest way to confuse your audience is by sharing too many details at once. The only data points you should share are those that significantly support your point — and ideally, one point per chart. To avoid the debacle of sheepishly translating hard-to-see numbers and labels, rehearse your presentation with colleagues sitting as far away as the actual audience would. While you’ve been working with the same chart for weeks or months, your audience will be exposed to it for mere seconds. Give them the best chance of comprehending your data by using simple, clear, and complete language to identify X and Y axes, pie pieces, bars, and other diagrammatic elements. Try to avoid abbreviations that aren’t obvious, and don’t assume labeled components on one slide will be remembered on subsequent slides. Every valuable chart or pie graph has an “Aha!” zone — a number or range of data that reveals something crucial to your point. Make sure you visually highlight the “Aha!” zone, reinforcing the moment by explaining it to your audience.

With so many ways to spin and distort information these days, a presentation needs to do more than simply share great ideas — it needs to support those ideas with credible data. That’s true whether you’re an executive pitching new business clients, a vendor selling her services, or a CEO making a case for change.

• JS Joel Schwartzberg oversees executive communications for a major national nonprofit, is a professional presentation coach, and is the author of Get to the Point! Sharpen Your Message and Make Your Words Matter and The Language of Leadership: How to Engage and Inspire Your Team . You can find him on LinkedIn and X. TheJoelTruth

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179 Best Database-Themed Templates for PowerPoint & Google Slides

With over 6 million presentation templates available for you to choose from, crystalgraphics is the award-winning provider of the world’s largest collection of templates for powerpoint and google slides. so, take your time and look around. you’ll like what you see whether you want 1 great template or an ongoing subscription, we've got affordable purchasing options and 24/7 download access to fit your needs. thanks to our unbeatable combination of quality, selection and unique customization options, crystalgraphics is the company you can count on for your presentation enhancement needs. just ask any of our thousands of satisfied customers from virtually every leading company around the world. they love our products. we think you will, too" id="category_description">crystalgraphics creates templates designed to make even average presentations look incredible. below you’ll see thumbnail sized previews of the title slides of a few of our 179 best database templates for powerpoint and google slides. the text you’ll see in in those slides is just example text. the database-related image or video you’ll see in the background of each title slide is designed to help you set the stage for your database-related topics and it is included with that template. in addition to the title slides, each of our templates comes with 17 additional slide layouts that you can use to create an unlimited number of presentation slides with your own added text and images. and every template is available in both widescreen and standard formats. with over 6 million presentation templates available for you to choose from, crystalgraphics is the award-winning provider of the world’s largest collection of templates for powerpoint and google slides. so, take your time and look around. you’ll like what you see whether you want 1 great template or an ongoing subscription, we've got affordable purchasing options and 24/7 download access to fit your needs. thanks to our unbeatable combination of quality, selection and unique customization options, crystalgraphics is the company you can count on for your presentation enhancement needs. just ask any of our thousands of satisfied customers from virtually every leading company around the world. they love our products. we think you will, too.

Widescreen (16:9) Presentation Templates. Change size...

Slide set consisting of fiber network server

A laptop with a white background and place for text

Three open laptops with a text that spells out the word "Database"

Slide deck having server tower against idyllic view of bright sun over cloudscape during sunny day

Theme featuring businessman typing on laptop with linked reports charts grapghs

Theme with woman climbing up ladder in archive

Theme enhanced with businessman in blockchain cryptocurrency concept backdrop

Presentation theme featuring person holding hologram screen displaying information from cloud based system

PPT layouts with program development concept young man working with computer

Presentation design with blockchain concept in database management

Slide set featuring catalog cards in library closeup

PPT layouts consisting of hand using laptop with database reports and online work concept

PPT layouts consisting of female hands touching tablet with white cloud concept

Slide set featuring businessman typing on laptop with linked reports charts grapghs

Presentation theme consisting of hand with marker writing crm backdrop

PPT layouts having businessman in blockchain cryptocurrency concept

Presentation featuring blockchain concept in database management

Presentation design with library or archive reference card catalog database knowledge base concept

Slides having blockchain concept in database management

PPT theme enhanced with cardboard boxes with documents on shelving unit in archive background

Presentation theme with closeup of business woman hand typing on keyboard and mouse

Presentation theme enhanced with hand using laptop with database reports and online work concept

PPT theme having businessman searching for big data

Slide set with woman accessing modern hologram personal database with fingerprint identification

Presentation theme consisting of old paper documents in archive closeup

PPT layouts having coded data on computer screen at workplace of modern programmer networking on background background

Presentation theme with library card archive or index toned image

Presentation theme with business woman hand typing on keyboard with online shopping concept background

PPT theme featuring close up of male hand touching virtual screen

PPT theme consisting of hard drives in data center

Slide set with man accessing modern hologram personal database with fingerprint identification

Presentation theme featuring group of people having a meeting with database insciption web security concept

PPT layouts enhanced with female hands touching tablet with white cloud concept backdrop

Slide set enhanced with young business man planing and solving problems with illustrated graph disply screen for database and statistycs

Theme having image of black laptop keyboard with female hands touching it backdrop

PPT theme enhanced with businessman in big data management concept

PPT layouts consisting of hand using laptop with database reports and online work concept backdrop

PPT layouts having hand using laptop with database reports and online work concept

Theme featuring digitally generated image of black mathematical symbol on hud interface screen copy space illustration computer database globalization machine learning and technology concept

Presentation theme having blockchain concept in database management

More database templates for powerpoint and google slides:.

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Introduction to Database Systems

Sep 07, 2014

1.13k likes | 2.73k Views

Introduction to Database Systems. Databases Database Management Systems (DBMS) Levels of Abstraction Data Models Database Languages Types of Users DBMS Function and Structure In other words, a somewhat random list of words and concepts that are necessary to move on…

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Presentation Transcript

Introduction to Database Systems • Databases • Database Management Systems (DBMS) • Levels of Abstraction • Data Models • Database Languages • Types of Users • DBMS Function and Structure In other words, a somewhat random list of words and concepts that are necessary to move on… Read Chapter 1, including the historical notes on pages 29 - 31.

Concept #1: Databases & Database Management Systems

What is a Database? • According to the book: • Collection of interrelated data • Set of programs to access the data • A DBMS contains information about a particular enterprise • DBMS provides an environment that is both convenient and efficient to use. • Another definition (know these): • A database is a collection of organized, interrelated data, typically relating to a particular enterprise • A Database Management System (DBMS) is a set of programs for managing and accessing databases

Some PopularDatabase Management Systems • Commercial “off-the-shelf” (COTS): • Oracle • IBM DB2 (IBM) • SQL Server (Microsoft) • Sybase • Informix (IBM) • Access (Microsoft) • Cache (Intersystems – nonrelational) • Open Source: • MySQL • PostgreSQL Note: This is not a course on any particular DBMS!

Some Database Applications • Anywhere there is data, there could be a database: • Banking - accounts, loans, customers • Airlines - reservations, schedules • Universities - registration, grades • Sales - customers, products, purchases • Manufacturing - production, inventory, orders, supply chain • Human resources - employee records, salaries, tax deductions • Course context is an “enterprise” that has requirements for: • Storage and management of 100’s of gigabytes or terabytes of data • Support for 100’s or more of concurrent users and transactions • Traditional supporting platform, e.g, HP ProLiant server, 16GB RAM, 50TB of disk space

Purpose of Database System • Prior to the availability of COTS DBMSs, database applications were built on top of file systems – coded from the ground up. • Drawbacks of this approach: • Difficult to reprogram sophisticated processing, i.e., concurrency control, backup and recovery, security • Re-inventing the wheel can be expensive and error-prone (ask NASA). • “We need a truck, lets design and build our own truck.”*** • According to the book, this leads to: • Data redundancy and inconsistency • Multiple files and formats • A new program to carry out each new task • Integrity constraints (e.g. account balance > 0) become embedded throughout program code, etc. • Database systems offer proven solutions for the above problems.

Purpose of Database Systems (Cont.) • Even to this day, engineers will occasionally propose custom-developed file systems. • So when should we code from scratch, and when do we buy a DBMS?? • How much data? • How sophisticated is the processing of that data? • How many concurrent users? • What level of security? • Is data integrity an issue? • Does the data change at all?

Concept #2: Levels of Abstraction

Levels of Abstraction • Physical level - defines low-level details about how data item is stored on disk. • Logical level - describes data stored in a database, and the relationships among the data (usually conveyed as a data model, e.g., an ER diagram). • View level - defines how information is presented to users. Views can also hide details of data types, and information (e.g., salary) for security purposes. • Physical data independence is the ability to modify the physical schema without having an impact on the logical or view levels. • Physical data independence is important in any database or DBMS.

Concept #3: Instances vs. Schemas

Instances vs. Schemas • The difference between a database schema and a database instance is similar to the difference between a data type and a variable in a program. • A database schema defines the structure or design of a database. • More precisely: • A logical schema defines a database design at the logical level; typically an entity-relationship (ER) or UML diagram. • A physical schema defines a database design at the physical level; typically a DDL file. • An instance of a database is the combination of the database and its’ contents at one point in time.

Concept #4: Data Models

What is a Data Model? • The phrase “data model” is used in a couple of different ways. • Frequently used (use #1) to refer to an overall approach or philosophy for database design and development. • For those individuals, groups and corporations that subscribe to a specific data model, that model permeates all aspects of database design, development, implementation, etc. • Current data models: • Relational model • Object-oriented model • Object-relational model • Semi, and non-structured data models • Various other NoSQL models • Legacy data models: • Network • Hierarchical

What is a Data Model, Cont? • During the early phases of database design and development, a “data model” is frequently developed (use #2). • The purpose of developing the data model is to define: • Data • Relationships between data items • Semantics of data items • Constraints on data items In other words, a data model defines the logical schema, i.e., the logical level of design of a database. • A data model is typically conveyed as one or more diagrams (e.g., ER or UML diagrams). • This early phase in database development is referred to as data modeling.

Entity-Relationship Diagrams Examples of entity-relationship diagrams: Authors current (UML-ish) notation: http://my.fit.edu/~pbernhar/Teaching/DatabaseSystems/Slides/University.ppt Older (Chen) notation: Widely used for database modeling.

A Sample Relational Database • Regardless of the model, the end result is the same – a relational database consisting of a collection of tables:

Concept #5: Query Languages

Query Languages A query language is used to create, manage, access, and modify data in a database. The list of query languages is quite long: http://en.wikipedia.org/wiki/Query_languages The most widely used query language is Structure Query Language (SQL). At a high-level, SQL consists of two parts: Data Definition Language (DDL) Data Manipulation Language (DML)

Data Definition Language (DDL) • DDL is used for defining a (physical) database schema (see the book for a more complete example): create table account ( account-number char(10), branch-name varchar(16), balance integer, primary key (account-number)) • Given a DDL file, the DDL compiler generates a set of tables. • The authors also define a subset of DDL called Data storage and definition language for specifying things such as: • Location on disk • Physical-level formatting • Access privledges

Data Manipulation Language (DML) • DML is used for accessing and manipulating a database. • Two classes of DMLs: • Procedural – user specifies how to get the required data. • Non-procedural – user specifies what data is required without specifying how to get that data. • SQL is usually referred to as a non-procedural query language.

SQL Examples • Find the name of the customer with customer-id 192-83-7465: selectcustomer.customer-namefromcustomerwherecustomer.customer-id = ‘192-83-7465’ • Find the balances of all accounts held by the customer with customer-id 192-83-7465: selectaccount.balancefromdepositor, accountwheredepositor.customer-id = ‘192-83-7465’ anddepositor.account-number = account.account-number • Databases are typically accessed by: • Users through a command line interface • Users through a query or software editing tool, e.g., MySQL Workbench • Application programs that (generally) access them through embedded SQL or an application program interface (e.g. ODBC/JDBC)

Concept #6: Database Users

Database Users Users are differentiated by the way they interact with the system: • Naïve users • Application programmers • Specialized users • Sophisticated users

Database Administrator (DBA) • The DBA coordinates all the activities of the database system; has a good understanding of the enterprise’s information resources and needs. • DBA duties: • Granting user authority to access the database • Acting as liaison with users • Installing and maintaining DBMS software • Monitoring performance and performance tuning • Backup and recovery • According to the book, the DBA is also responsible for: • Logical and Physical schema definition and modification • Access method definition • Specifying integrity constraints • Responding to changes in requirements • These latter tasks are frequently performed by a software or systems engineer specialized in database design.

Concept #7: DBMS Structure

Overall DBMS Structure Query Optimizer

Overall DBMS Structure Users, Programs Queries Commands Query Processor DML Compiler DDL Interpreter Parser, etc. HLL Compiler & Linker Optimizer Query Evaluation Engine Storage Manager Buffer Manager Authorization & Integrity Manager File Manager Transaction Manager Backup & Recovery Concurrency Control Storage Data Data Dictionary Indices Statistical Data

Overall DBMS Structure The following components of a DBMS are of interest to us: • transaction manager • buffer manager • file manager • authorization and integrity manager • query optimizer

Transaction Management • A transaction is a collection of operations that performs a single logical function in a database application • The transaction manager performs two primary functions: • backup and recovery • concurrency control • Backup and recoveryensures that the database remains in a consistent (correct) state despite failures: • system, power, network failures • operating system crashes • transaction failures. • Concurrency-controlinvolves managing the interactions among concurrent transactions.

Storage Management • The buffer manager loads data into main memory from disk as it is needed by the DBMS, and writes it back out when necessary. • The buffer manager is responsible for: • loading pages of data from disk into a segment of main memory called “the buffer”; sometimes also called the “cache.” • determining which pages in the buffer get replaced, when necessary. • writing pages back out to disk, when necessary. • managing the overall configuration of the buffer, decomposition into memory pools, page time-stamps, etc. • Sound familiar?

Storage Management • The file manager is responsible for managing the files that store data. • formatting the data files • managing the space in the data files • defragmenting the data files • inserting and deleting specific data from the files

Authorization & Integrity Management • The authorization & integrity manager performs two primary functions: • data security • data integrity • Data security: • ensure that unauthorized users can’t access the database • ensure that authorized users can only access appropriate data • Data integrity: • in general, maintains & enforces integrity constraints • maintains data relationships in the presence of data modifications • prevents modifications that would corrupt established data relationships

Query Optimization • A given query can be implemented by a DBMS in many different ways. • The query optimizer attempts to determine the most efficient way to execute a given query. • The resulting strategy for implementing a given query is referred to as a query plan.

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Database Design: Tips for Effectively Presenting Data

Databases are useful for any business but sometimes inaccessible. Can you employ database design to make data user-friendly? Absolutely, and we’ll teach you how.

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Databases are essential for businesses to organize the structure, document processes and make it easier to maneuver through all the data information systems. Here is how database design can help increase usability and user-friendliness in and outside your organization.

Let’s start from the basics: what is database design, anyway? As the name suggests, it’s the creation of databases, or storing and presenting data according to a specific database model.

But there’s more to it than meets the eye. If you want to know how to design a database, you need to be clear on two things:

• What information are you using, and how is it organized
• How are you presenting the information

The first will highly depend on the database at hand, as well its intended purpose/audience. Something you want to use internally in your company/organization will likely be a lot more detailed, than a concise version you put out for a wider audience.

On the other hand, learning how to design a database visually is something we can help with. Although this is an often overlooked aspect, database design can greatly improve the user experience , and therefore make your databases an even more valuable resource.

Additionally, good graphics and information design also become a strong competitive advantage. For example, if you share your databases with customers, as is often the case with real estate databases ).In this article, we’ll offer five practical uses of graphic design to enhance the look of your database.

5 Ideas to help with designing a database

So you’ve done the work and gathered some useful data. Awesome! Now it’s time to transform it into a visually appealing database that you can use.

Here are some design elements and ideas to guide you.

Infographics and charts

One of the most valuable elements in designing databases are charts and infographics. Given that people's attention spans are shortening by the day, it's understandable that we'd like to make complex material more digestible in this way.

Infographics and charts come in a variety of shapes and sizes, including:

• Statistical : These can be basic graphs and charts, as well as infographics that convey study findings and figures. You may use them in combination with other visual components such as icons to make them more attractive. They usually contain little text.
• Informational : Used to convey several bits of data in a logical order. They're commonly broken up into sections with distinct titles and more text than statistical infographics.
• Timeline : This is a great way to show how anything evolved, whether it's historical events or a project. Design can assist you in highlighting changes over a certain period of time.
• Process : A term used to describe the stages involved in a particular procedure. Because they're chronological, the sequence of items (left to right, top to bottom) is a major design consideration. Design features like arrows also help consumers follow the stages in the correct order.
• Comparison : Perhaps one of the most common forms of infographics. People frequently provide a visual comparison of two (or more) items. This is a fantastic idea for those looking to share data insights with a broader audience (e.g., your customers).

You might know that most marketers agree that infographics are the most effective content marketing asset . But are they as effective in databases?

Absolutely. The main advantage of infographics is significant informational value . They are a way to pack tons of critical data into one digestible format. Excel spreadsheets and extensive reports are suitable for comprehensive data entries and in-depth analyses. Infographics, on the other hand, are the perfect way to present the key takeaways.

They’re also a great way to summarize end-of-the-year results and share them within your organization (or externally).

You can find heaps of useful database design examples on Miro Community , such as these  visually engaging boards for a training course.  

Source: ManyPixels

Of course, if you're creating something that will be shared outside or within your organization, you must make sure the visuals follow your brand's color guidelines.

Infographic design by ManyPixels

Process workflow maps

Process mapping is a visual representation of a workflow that allows a team to better understand a process and its components. Workflow maps are different from a process infographic because the latter doesn’t always present a process. Sometimes, these infographics explain the structure or organization of a project, company, document, etc.

If done well, process workflow maps can be a tremendous time-saving asset . Why waste hours in a training session when you can create a process workflow that allows each new team member to grasp the ins and outs of a particular process quickly.

A process map can also show the specific phases in a process, who is responsible for what, and when. This is especially useful for involving stakeholders in processes and identifying opportunities for improvement. Most process maps begin at a high level and then go into further depth as needed.

The following are a few examples of process maps:

• Comprehensive process map
• Document map
• High-level process map
• Rendered process map
• Value-added chain diagram  
• Value-stream map  
• Flow diagram  
• Process flowchart  
• Process model
• Workflow diagram

Typically, these visual diagrams are part of a company's business process management (BPM) . This is the name given to a series of methods used to discover, model, analyze, measure, and optimize all the processes that comprise the running of a business.

Color organization

In database designing, color isn’t merely a stylistic choice. The colors you use in database design can significantly affect its user friendliness.

When desining a database of tasks you can use different colors to map the stage of each task, for example, yellow for 'in progress,' pink for 'pending,' green for 'done,' and red for 'stuck.'

The choice of colors in data visualization shouldn’t be arbitrary . Contrast can help you draw attention to the essential items. But overusing contrast or bold colors can have the opposite effect: cause confusion and fatigue in the viewer.

In this example of a presentation design created for one of ManyPixels’ clients, you can see how the designer employed color and contrast to add visual weight to different elements. One of the slides is a quote or a question that the viewer should consider before looking at the numbers. In another, the key takeaway is placed against the colorful background.

Usage of images and illustrations

What is database design without suitable images? Databases are typically dense with data, so seeing a lot of text and submenus on them might make people feel overwhelmed and bounce off the page.

Adding impressive visual design between large sections of text may assist page visitors in "taking a break" while also learning more about the subject matter they're reading.

There’s a common misconception that illustrations always appear unprofessional or even childish. In modern marketing and branding, nothing could be further from the truth. Illustrations come in various styles that can fit virtually any business or industry . Luckily, there are plenty of great online resources where you can find custom illustrations, such as the ManyPixels free illustration library !

Of course, it's also imperative to consider how illustrations interact with other design elements.

For example, this design informs people about proper legal actions in the case of a traffic accident. The illustrations help viewers identify with the situation better. Still, it doesn't seem overbearing or unpleasant to look at: who would want to look at photos of a car crash for an extended period?

Although it's commonly associated with optimism and communication, the yellow color works perfectly here since it's a color often found in traffic signs and notices, thanks to its visibility.

The importance of a practical layout

A non-designer will always think of colors, fonts, and images first. But a professional database designer knows that making sure all these elements work together is equally important.

This is where knowledge of design principles plays a critical role in any design, especially databases and data visualization. Understanding how to apply principles such as hierarchy, balance, and proximity ensures that the data isn't just shown but presented in a user-friendly manner.

Considering the correct layout is rarely only a matter of aesthetic appeal. .It’s one of database design basics that requires thought and testing. You need to consider the order of information (also called information architecture), how the most critical pieces of data are presented, and how viewers navigate the database to create an optimal database structure.

Whether it’s a simple Excel design or a highly customizable database in a tool like Miro , it’s always possible to ensure the layout serves your purpose.

Final thoughts

We hope these tips will help you transform boring databases into engaging, valuable assets for your organization.

There are plenty of nifty online tools you can use for things like creating flowcharts or process maps. But remember that no matter how appealing a template looks, the chances of it being perfectly suited to your needs are slim.

That's why it's always a good idea to hire a professional database designer who can help you translate your astute knowledge of data into graphics that anyone can understand .

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Fast & reliable, fixed monthly rate, flexible & scalable, pro designers, presentation design by the pros.

Get inspired with some of ManyPixels best presentation designs. Download our portfolio to check them out!

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Combining Cryptography and Other Techniques for Various Privacy-Preserving Applications

Description.

Abstract. Secure multiparty computation (SMPC), fully homomorphic encryption (FHE) and differential privacy (DP) is a selection of Privacy-Enhancing Technologies (PETs) that protect input data confidentiality and enable the computation of a function without revealing the input data. Using PETs, one can keep sensitive data private and at the same time derive valuable insights from data analysis, optimizing the privacy-utility tradeoff. In this talk, we will introduce and compare different PETs in order to assist in selecting the most suitable options for a given application and show that they aren't a one-size-fits-all solution. We will present two applications, the first one is genomic data machine learning and second one is financial fraud detection.

Suggested readings: Suggested readings: ia.cr/2021/733 , doi: 10.1007/s00145-023-09464-4 , HyPETs workshop

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Security and Privacy: cryptography

AI Index: State of AI in 13 Charts

In the new report, foundation models dominate, benchmarks fall, prices skyrocket, and on the global stage, the U.S. overshadows.

This year’s AI Index — a 500-page report tracking 2023’s worldwide trends in AI — is out.

The index is an independent initiative at the Stanford Institute for Human-Centered Artificial Intelligence (HAI), led by the AI Index Steering Committee, an interdisciplinary group of experts from across academia and industry. This year’s report covers the rise of multimodal foundation models, major cash investments into generative AI, new performance benchmarks, shifting global opinions, and new major regulations.

Don’t have an afternoon to pore through the findings? Check out the high level here.

A Move Toward Open-Sourced

This past year, organizations released 149 foundation models, more than double the number released in 2022. Of these newly released models, 65.7% were open-source (meaning they can be freely used and modified by anyone), compared with only 44.4% in 2022 and 33.3% in 2021.

But At a Cost of Performance?

Closed-source models still outperform their open-sourced counterparts. On 10 selected benchmarks, closed models achieved a median performance advantage of 24.2%, with differences ranging from as little as 4.0% on mathematical tasks like GSM8K to as much as 317.7% on agentic tasks like AgentBench.

Biggest Players

Industry dominates AI, especially in building and releasing foundation models. This past year Google edged out other industry players in releasing the most models, including Gemini and RT-2. In fact, since 2019, Google has led in releasing the most foundation models, with a total of 40, followed by OpenAI with 20. Academia trails industry: This past year, UC Berkeley released three models and Stanford two.

Industry Dwarfs All

If you needed more striking evidence that corporate AI is the only player in the room right now, this should do it. In 2023, industry accounted for 72% of all new foundation models.

Prices Skyrocket

One of the reasons academia and government have been edged out of the AI race: the exponential increase in cost of training these giant models. Google’s Gemini Ultra cost an estimated $191 million worth of compute to train, while OpenAI’s GPT-4 cost an estimated $78 million. In comparison, in 2017, the original Transformer model, which introduced the architecture that underpins virtually every modern LLM, cost around $900.

What AI Race?

At least in terms of notable machine learning models, the United States vastly outpaced other countries in 2023, developing a total of 61 models in 2023. Since 2019, the U.S. has consistently led in originating the majority of notable models, followed by China and the UK.

Move Over, Human

As of 2023, AI has hit human-level performance on many significant AI benchmarks, from those testing reading comprehension to visual reasoning. Still, it falls just short on some benchmarks like competition-level math. Because AI has been blasting past so many standard benchmarks, AI scholars have had to create new and more difficult challenges. This year’s index also tracked several of these new benchmarks, including those for tasks in coding, advanced reasoning, and agentic behavior.

Private Investment Drops (But We See You, GenAI)

While AI private investment has steadily dropped since 2021, generative AI is gaining steam. In 2023, the sector attracted $25.2 billion, nearly ninefold the investment of 2022 and about 30 times the amount from 2019 (call it the ChatGPT effect). Generative AI accounted for over a quarter of all AI-related private investments in 2023.

U.S. Wins $$ Race

And again, in 2023 the United States dominates in AI private investment. In 2023, the $67.2 billion invested in the U.S. was roughly 8.7 times greater than the amount invested in the next highest country, China, and 17.8 times the amount invested in the United Kingdom. That lineup looks the same when zooming out: Cumulatively since 2013, the United States leads investments at $335.2 billion, followed by China with $103.7 billion, and the United Kingdom at $22.3 billion.

Where is Corporate Adoption?

More companies are implementing AI in some part of their business: In surveys, 55% of organizations said they were using AI in 2023, up from 50% in 2022 and 20% in 2017. Businesses report using AI to automate contact centers, personalize content, and acquire new customers. 

Younger and Wealthier People Worry About Jobs

Globally, most people expect AI to change their jobs, and more than a third expect AI to replace them. Younger generations — Gen Z and millennials — anticipate more substantial effects from AI compared with older generations like Gen X and baby boomers. Specifically, 66% of Gen Z compared with 46% of boomer respondents believe AI will significantly affect their current jobs. Meanwhile, individuals with higher incomes, more education, and decision-making roles foresee AI having a great impact on their employment.

While the Commonwealth Worries About AI Products

When asked in a survey about whether AI products and services make you nervous, 69% of Aussies and 65% of Brits said yes. Japan is the least worried about their AI products at 23%.  

Regulation Rallies

More American regulatory agencies are passing regulations to protect citizens and govern the use of AI tools and data. For example, the Copyright Office and the Library of Congress passed copyright registration guidance concerning works that contained material generated by AI, while the Securities and Exchange Commission developed a cybersecurity risk management strategy, governance, and incident disclosure plan. The agencies to pass the most regulation were the Executive Office of the President and the Commerce Department. 

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Fate Therapeutics Announces Presentation of FT819 Proof-of-Concept Data for B cell-mediated Autoimmune Diseases at ASGCT Annual Meeting

Key Therapeutic Mechanisms of Clinical Activity for Autoimmune Diseases, including B cell Depletion, Tissue Infiltration and Immune Reconstitution Data, from Phase 1 Study of FT819 in Relapsed / Refractory B-cell Malignancies to be Highlighted

Patient Enrollment Initiated in Phase 1 Study of FT819 Off-the-shelf, CD19-targeted, iPSC-derived CAR T-cell Therapy for Systemic Lupus Erythematosus

SAN DIEGO, April 22, 2024 (GLOBE NEWSWIRE) -- Fate Therapeutics, Inc. (NASDAQ: FATE), a clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients with cancer and autoimmune diseases, today announced that two presentations will be featured at the American Society of Gene and Cell Therapy (ASGCT) 27 th Annual Meeting, being held in Baltimore, Maryland on May 7-11, 2024.

The Company will present data of key therapeutic mechanisms of activity for autoimmune diseases, including B cell depletion, tissue infiltration and immune reconstitution, from its Phase 1 study of FT819 in relapsed / refractory B-cell malignancies. FT819 is the Company’s off-the-shelf, CD19-targeted, iPSC-derived CAR T-cell program, which is also being investigated in a Phase 1 study for patients with moderate-to-severe systemic lupus erythematosus (SLE) including lupus nephritis and extrarenal lupus (NCT06308978). In addition, the Company will highlight preclinical data from its off-the-shelf, iPSC-derived, CAR T-cell product platform for solid tumors, with an oral presentation of a novel MICA/B-targeted CAR T-cell product candidate that is designed to target a broad array of tumor types and to overcome immune cell evasion by shedding of stress ligands.

Accepted abstracts are available on the ASGCT Annual Meeting website. Presentations details are as follows:

Presentations

FT819-102: Clinical translation of off-the-shelf, TCR-less, CD8αβ+ anti-CD19 CAR-T cells for the treatment of B cell-mediated autoimmune disorders Abstract Number: 1415 Session: Cell Therapy and Cell-Based Gene Therapy Trials Location: Exhibit Hall Presentation Date / Time: Thursday, May 9, 2024 12:00 PM

Novel α3-MICA/B-specific CAR T-cell immunotherapy demonstrates ubiquitous targeting of cancer cells and resistance to immune-surveillance evasion Abstract Number: 45 Session: Genetically Modified Immune Cells for Malignant and Non-Malignant Diseases Location: Room 307-308 Presentation Date / Time: Tuesday May 7, 2024 3:00 PM

About Fate Therapeutics’ iPSC Product Platform Human induced pluripotent stem cells (iPSCs) possess the unique dual properties of unlimited self-renewal and differentiation potential into all cell types of the body. The Company’s proprietary iPSC product platform combines multiplexed-engineering of human iPSCs with single-cell selection to create clonal master iPSC lines. Analogous to master cell lines used to mass produce biopharmaceutical drug products such as monoclonal antibodies, the Company utilizes its clonal master iPSC lines as a starting cell source to manufacture engineered cell products which are well-defined and uniform in composition, can be stored in inventory for off-the-shelf availability, can be combined and administered with other therapies, and can potentially reach a broad patient population. As a result, the Company’s platform is uniquely designed to overcome numerous limitations associated with the manufacture of cell therapies using patient- or donor-sourced cells. Fate Therapeutics’ iPSC product platform is supported by an intellectual property portfolio of over 500 issued patents and 500 pending patent applications.

About Fate Therapeutics, Inc. Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients with cancer and autoimmune diseases. Using its proprietary iPSC product platform, the Company has established a leadership position in creating multiplexed-engineered master iPSC lines and in the manufacture and clinical development of off-the-shelf, iPSC-derived cell products. The Company’s pipeline includes iPSC-derived natural killer (NK) cell and T-cell product candidates, which are selectively designed, incorporate novel synthetic controls of cell function, and are intended to deliver multiple therapeutic mechanisms to patients. Fate Therapeutics is headquartered in San Diego, CA. For more information, please visit www.fatetherapeutics.com.

Forward-Looking Statements This release contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995 including statements regarding the advancement of and plans related to the Company's product candidates, clinical studies and preclinical research and development programs, the Company’s progress, plans and timelines for the clinical investigation of its product candidates, including the initiation and continuation of enrollment in the Company’s clinical trials, the timing and availability of data from the Company’s clinical trials, the therapeutic and market potential of the Company’s research and development programs and product candidates, and the potential capabilities and benefits of the Company’s iPSC product platform. These and any other forward-looking statements in this release are based on management's current expectations of future events and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in or implied by such forward-looking statements. These risks and uncertainties include, but are not limited to, the risk that the Company’s research and development programs and product candidates, including those product candidates in clinical investigation, may not demonstrate the requisite safety, efficacy, or other attributes to warrant further development or to achieve regulatory approval, the risk that results observed in prior studies of the Company’s product candidates, including preclinical studies and clinical trials, will not be observed in ongoing or future studies involving these product candidates, the risk of a delay or difficulties in the manufacturing of the Company’s product candidates or in the initiation and conduct of, or enrollment of patients in, any clinical trials, the risk that the Company may cease or delay preclinical or clinical development of any of its product candidates for a variety of reasons (including requirements that may be imposed by regulatory authorities on the initiation or conduct of clinical trials, changes in the therapeutic, regulatory, or competitive landscape for which the Company’s product candidates are being developed, the amount and type of data to be generated or otherwise to support regulatory approval, difficulties or delays in patient enrollment and continuation in the Company’s ongoing and planned clinical trials, difficulties in manufacturing or supplying the Company’s product candidates for clinical testing, failure to demonstrate that a product candidate has the requisite safety, efficacy, or other attributes to warrant further development, and any adverse events or other negative results that may be observed during preclinical or clinical development), and the risk that its product candidates may not produce therapeutic benefits or may cause other unanticipated adverse effects. For a discussion of other risks and uncertainties, and other important factors, any of which could cause the Company’s actual results to differ from those contained in the forward-looking statements, see the risks and uncertainties detailed in the Company’s periodic filings with the Securities and Exchange Commission, including but not limited to the Company’s most recently filed periodic report, and from time to time in the Company’s press releases and other investor communications. Fate Therapeutics is providing the information in this release as of this date and does not undertake any obligation to update any forward-looking statements contained in this release as a result of new information, future events or otherwise.

Contact: Christina Tartaglia Stern Investor Relations, Inc. 212.362.1200 [email protected]

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Leaked presentation reveals Microsoft's astounding plan to ramp up data-center capacity for the AI boom

• Microsoft's data-center capacity jumped in recent quarters, a leaked internal presentation shows.
• The company is planning even faster data-center growth in the coming quarters.
• Microsoft delivered "record-level GPU capacity," according to the presentation.

Microsoft significantly expanded its data-center capacity recently and plans to ramp up growth to astounding levels going forward, according to an internal document obtained by Business Insider.

Since July 2023, the start of Microsoft's latest fiscal year, the company delivered more than 500 megawatts of new data-center capacity , the document disclosed.

This document was part of a confidential slide deck from the company's Cloud Operations and Innovation team that was presented earlier this year.

Under the heading "Commercial Cloud and AI Demands: Fueling our Expansion," the document said Microsoft surpassed 5 gigawatts of total data-center installed capacity in the first half of its latest fiscal year.

The rise of generative artificial intelligence and huge foundation models is fueling a new data-center boom . Microsoft is leading the way through its partnership with OpenAI , the startup behind ChatGPT and GPT-4 .

These AI models need to be trained on mountains of data and then fine-tuned intensely. That takes thousands of GPUs and a pile of other related gear that's housed in huge data centers. These facilities use so much power that their capacity is measured in megawatts and gigawatts of electricity.

Shaolei Ren , an electrical and computer engineering professor at the University of California, Riverside, said Microsoft's 5 gigawatts of installed data-center capacity, if fully used, would be equivalent to Hong Kong or Portugal's annual electricity consumption.

"Astonishing speed"

It doesn't stop there. The software giant laid out even more radical growth plans for its data-center empire in the document obtained by BI.

Related stories

"With a strong Commercial Cloud business, our goal is clear," Microsoft said in this part of the slide presentation.

Microsoft wants to double new data-center capacity in the second half of its fiscal year. This runs from early 2024 to the middle of this year.

In the first half of Microsoft's 2025 fiscal year, which runs from early July through the end of 2024, the company aims to "achieve 3x growth" in new data-center capacity.

This requires Microsoft to deliver more than 200 megawatts in data-center capacity every month.

"This is an astonishing speed," Ren told BI. "This is a very large data-center capacity."

Ren said Microsoft's capacity plans suggested the company was either seeing huge demand or simply wanting to stay competitive by securing future power capacity that otherwise might be taken by competitors.

He added that this also raised questions about the environmental consequences of adding such a large data-center footprint, given the carbon emissions and water consumption of the facilities.

A Microsoft spokesperson declined to comment.

'Record-level GPU capacity'

The company is also securing a record number of GPUs to handle new AI workloads in data centers.

In the second half of last year, Microsoft delivered "record-level GPU capacity," more than doubling its total installed GPU base, the document said, without mentioning actual numbers.

Microsoft's GPU footprint expanded into 39 additional data centers in this period, and the company now has "AI clusters" live in 98 locations globally.

Contact the reporter, Eugene Kim, via the encrypted-messaging apps Signal or Telegram ( +1-650-942-3061 ) or email ( [email protected] ). Reach out using a nonwork device. Check out Business Insider's source guide for other tips on sharing information securely.

Axel Springer, Business Insider's parent company, has a global deal to allow OpenAI to train its models on its media brands' reporting.

Watch: How tech layoffs could affect the economy

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Excision BioTherapeutics Announces Oral Presentation Highlighting Positive Data from its HBV Program, EBT-107, at the Upcoming ASGCT 2024 Annual Meeting

SAN FRANCISCO, April 22, 2024 (GLOBE NEWSWIRE) -- Excision BioTherapeutics, Inc. (“Excision”, the “Company”), a clinical-stage biotechnology company developing CRISPR-based therapies to cure serious latent viral infectious diseases, today announced that it will present positive data from its program for Hepatitis B virus (HBV) at the American Society of Gene & Cell Therapy (ASGCT) 2024 Annual Meeting taking place May 7-11, 2024 in Baltimore, Maryland.

HBV is one of the most prevalent infectious diseases worldwide that lacks curative therapies. While existing antiviral and immunomodulator treatments slow liver damage by reducing viral load, they fail to eliminate covalently closed circular DNA (cccDNA) that enables persistent viral infection. Excision’s lead product candidate for the treatment of HBV infection, EBT-107, uses dual guide RNAs to effectively deactivate the virus and prevent the emergence of escape variants.

“Our proof-of-concept study demonstrates the efficacy of our dual guide-RNA-mediated editing strategy in significantly reducing viral HBV biomarkers in serum and intrahepatic HBV levels, indicating that HBV DNA cutting facilitates its degradation in vivo ,” said Daniel Dornbusch, Chief Executive Officer of Excision. “We believe that these data further validate our HBV program and will help progress our EBT-107 program toward an anticipated IND.”

The details of the presentations are below:

Title: Non-Viral Gene Editing with Dual Guide RNAs for Chronic Hepatitis B Infection Excision Program : HBV Session Type: Oral presentation Session Title: Gene Disruption and Excision Abstract: 153 Presenter: Ryo Takeuchi, Excision BioTherapeutics Location: Ballroom 3 Date/Time: May 09, 2024, 2:21 to 2:38 pm (EST)

Leveraging our proprietary computational approach, we identified multiple nucleases and guide pairs targeting conserved sites within the HBV genome, prioritizing those with minimal sequence identity to human genetic sequences, to mitigate off-target editing. Through screening reporter cell lines with integrated partial HBV genome, we identified pairs of guide RNAs that efficiently deleted sequences between target sites found in a wide range of HBV isolates. Testing a selected combination of editing nucleases and paired guide RNAs in HBV-infected cells, we observed decreased copies of total HBV DNA. Upon intravenous administration of a lipid nanoparticle (LNP) encapsulating an editing nuclease-encoding mRNA and a pair of guide RNAs in the HBV mouse model established with AAV-HBV, we observed a significant reduction of HBV biomarkers in serum and intrahepatic HBV.

About Excision BioTherapeutics, Inc. Excision BioTherapeutics, Inc. develops CRISPR-based medicines as potential cures for serious viral latent infectious diseases. The Company’s proprietary, multiplexed gene editing platform unites CRISPR technologies with a novel gene editing approach which demonstrated the ability to stop viral replication. Excision’s pipeline targets large, underserved markets including herpes simplex virus (HSV-1 keratitis), hepatitis B virus (HBV), and human immunodeficiency virus-1 (HIV-1). Excision’s foundational technologies were developed in the laboratories of Dr. Kamel Khalili at Temple University and Dr. Jennifer Doudna at the University of California, Berkeley. For more information, please visit www.excision.bio.

Contact: John Fraunces LifeSci Advisors 917-355-2395 [email protected]

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